LNX2 and MDGA1

Number of citations of the paper that reports this interaction (PubMedID 22889411)
17

Data Source:
BioGRID (two hybrid)

		LNX2	MDGA1
Description		ligand of numb-protein X 2	MAM domain containing glycosylphosphatidylinositol anchor 1
Image
GO Annotations	Cellular Component		Extracellular Region Extracellular Space Golgi Apparatus Plasma Membrane Anchored Component Of Plasma Membrane GABA-ergic Synapse
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding PDZ Domain Binding Identical Protein Binding Metal Ion Binding	Molecular_function
	Biological Process	Protein Ubiquitination	Neuron Migration Brain Development Spinal Cord Association Neuron Differentiation Cerebral Cortex Radially Oriented Cell Migration Regulation Of Synaptic Membrane Adhesion Regulation Of Presynapse Assembly
Pathways			Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Body mass index ( 26426971 28892062) Large B-cell lymphoma ( 21471979) Mean platelet volume ( 32888494 27863252) Night sleep phenotypes ( 27126917) Platelet distribution width ( 32888494 27863252) Response to cytadine analogues (cytosine arabinoside) ( 24483146)	Acne (severe) ( 24927181) Chronotype ( 30696823) Coronary artery aneurysm in Kawasaki disease ( 27171184) Daytime nap ( 33568662) Insomnia symptoms (never/rarely vs. sometimes/usually) ( 30804566) Insomnia symptoms (never/rarely vs. usually) ( 30804566) Lamb consumption ( 32066663) Neurological blood protein biomarker levels ( 31320639) Restless legs syndrome ( 29029846)
Interacting Genes		90 interacting genes: ATP5F1B C10orf88 CABP4 CBX4 CCT3 CDK2 CDK4 CDKN2C CRK CXADR DDA1 DRAP1 EAF2 FANCG FHL3 GADD45A GJD2 GLRX3 GRAP2 GRB2 IGSF5 IL16 INMT IP6K2 L3MBTL2 LGALS14 LNX1 LRRC8E MAP2K5 MAPK9 MCM7 MDGA1 MLX MRFAP1L1 MSRB3 MYLIP NAGK NMD3 NOTCH1 NTAQ1 NUDT14 NUMB OPTN PAN3 PARVG PDZRN3 PDZRN4 PEG10 PHYKPL PIK3R1 PIK3R3 PKDREJ POLR1C PPIH PPIL1 PSMD5 PSMF1 PTCD3 RAB6B RBM17 RLIM RNF138 ROPN1 RPA2 SCLY SCNM1 SFN SH3GLB2 SHISA2 SHTN1 SMARCB1 SRSF11 TAB1 TBC1D7 TCL1A TIFA TRAF1 TRAF2 TUBB UBE2D2 UBE2H UBE2I UBE2T UBE2Z USP2 VTN YJU2 ZNF148 ZNF410 ZNF581	2 interacting genes: LNX2 NLGN2
Entrez ID		222484	266727
HPRD ID		10042	14374
Ensembl ID		ENSG00000139517	ENSG00000112139
Uniprot IDs		Q8N448	Q8NFP4
PDB IDs		2VWR 5DIN 5E11 5E1Y 5E21 5E22	5V5V 5V5W 5XEQ
Enriched GO Terms of Interacting Partners?
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