LNX2 and RNF138

Number of citations of the paper that reports this interaction (PubMedID 22493164)
7

Data Source:
BioGRID (two hybrid)

		LNX2	RNF138
Description		ligand of numb-protein X 2	ring finger protein 138
Image			No pdb structure
GO Annotations	Cellular Component		Nucleus Site Of Double-strand Break
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding PDZ Domain Binding Identical Protein Binding Metal Ion Binding	Single-stranded DNA Binding Protein Binding Protein Kinase Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein Ubiquitination	Double-strand Break Repair Via Homologous Recombination DNA Double-strand Break Processing Involved In Repair Via Single-strand Annealing Wnt Signaling Pathway Protein Ubiquitination
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Body mass index ( 26426971 28892062) Large B-cell lymphoma ( 21471979) Mean platelet volume ( 32888494 27863252) Night sleep phenotypes ( 27126917) Platelet distribution width ( 32888494 27863252) Response to cytadine analogues (cytosine arabinoside) ( 24483146)
Interacting Genes		90 interacting genes: ATP5F1B C10orf88 CABP4 CBX4 CCT3 CDK2 CDK4 CDKN2C CRK CXADR DDA1 DRAP1 EAF2 FANCG FHL3 GADD45A GJD2 GLRX3 GRAP2 GRB2 IGSF5 IL16 INMT IP6K2 L3MBTL2 LGALS14 LNX1 LRRC8E MAP2K5 MAPK9 MCM7 MDGA1 MLX MRFAP1L1 MSRB3 MYLIP NAGK NMD3 NOTCH1 NTAQ1 NUDT14 NUMB OPTN PAN3 PARVG PDZRN3 PDZRN4 PEG10 PHYKPL PIK3R1 PIK3R3 PKDREJ POLR1C PPIH PPIL1 PSMD5 PSMF1 PTCD3 RAB6B RBM17 RLIM RNF138 ROPN1 RPA2 SCLY SCNM1 SFN SH3GLB2 SHISA2 SHTN1 SMARCB1 SRSF11 TAB1 TBC1D7 TCL1A TIFA TRAF1 TRAF2 TUBB UBE2D2 UBE2H UBE2I UBE2T UBE2Z USP2 VTN YJU2 ZNF148 ZNF410 ZNF581	17 interacting genes: APP CFAP206 EFEMP2 H3C1 LNX2 NTAQ1 PCBP4 QKI RAD51D TAF9 TCF7L2 TP53 TRIM8 UBE2D2 UBE2D4 UBE2K UBE2W
Entrez ID		222484	51444
HPRD ID		10042	11508
Ensembl ID		ENSG00000139517	ENSG00000134758
Uniprot IDs		Q8N448	A0A140VJT9 Q8WVD3
PDB IDs		2VWR 5DIN 5E11 5E1Y 5E21 5E22
Enriched GO Terms of Interacting Partners?
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