LNX2 and ZNF581

Number of citations of the paper that reports this interaction (PubMedID 27107012)
40

Data Source:
BioGRID (two hybrid)

		LNX2	ZNF581
Description		ligand of numb-protein X 2	zinc finger protein 581
Image			No pdb structure
GO Annotations	Cellular Component		Nucleus
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding PDZ Domain Binding Identical Protein Binding Metal Ion Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding
	Biological Process	Protein Ubiquitination	Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Body mass index ( 26426971 28892062) Large B-cell lymphoma ( 21471979) Mean platelet volume ( 32888494 27863252) Night sleep phenotypes ( 27126917) Platelet distribution width ( 32888494 27863252) Response to cytadine analogues (cytosine arabinoside) ( 24483146)
Interacting Genes		90 interacting genes: ATP5F1B C10orf88 CABP4 CBX4 CCT3 CDK2 CDK4 CDKN2C CRK CXADR DDA1 DRAP1 EAF2 FANCG FHL3 GADD45A GJD2 GLRX3 GRAP2 GRB2 IGSF5 IL16 INMT IP6K2 L3MBTL2 LGALS14 LNX1 LRRC8E MAP2K5 MAPK9 MCM7 MDGA1 MLX MRFAP1L1 MSRB3 MYLIP NAGK NMD3 NOTCH1 NTAQ1 NUDT14 NUMB OPTN PAN3 PARVG PDZRN3 PDZRN4 PEG10 PHYKPL PIK3R1 PIK3R3 PKDREJ POLR1C PPIH PPIL1 PSMD5 PSMF1 PTCD3 RAB6B RBM17 RLIM RNF138 ROPN1 RPA2 SCLY SCNM1 SFN SH3GLB2 SHISA2 SHTN1 SMARCB1 SRSF11 TAB1 TBC1D7 TCL1A TIFA TRAF1 TRAF2 TUBB UBE2D2 UBE2H UBE2I UBE2T UBE2Z USP2 VTN YJU2 ZNF148 ZNF410 ZNF581	96 interacting genes: AP2M1 APOBEC3C APP ASB13 ATG9A BANP BOLA2 BOLA2B CALCOCO2 CARD10 CBY2 CCDC136 CCNDBP1 CHURC1 CNFN CYSRT1 DAZAP2 DOCK8 DVL2 DVL3 EFEMP2 ENKD1 ETFDH FAM90A1 FANCL FHL5 FSD2 GOLGA2 GOLGA6L9 GOPC GPSM3 HMBOX1 HNRNPC HNRNPF HSF2BP IKZF1 IL16 KDM1A KHDRBS2 KRT27 KRT34 KRT40 KRTAP1-1 KRTAP10-1 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP2-3 KRTAP2-4 KRTAP4-12 KRTAP4-2 KRTAP5-9 KRTAP6-2 LNX1 LNX2 LZTS2 MDFI MGAT5B MTUS2 NAT14 NBPF19 NID2 NOTCH2NLA NUDT22 PDE4DIP PLAGL2 PLEKHF2 PLSCR1 PNMA1 POU2AF1 PRKAB2 RBPMS RIMBP3C RSKR SDCBP2 SERTAD2 SMARCC1 SOX5 SPAG8 SPG21 SUV39H1 TEKT4 TMCC2 TRAF1 TRAF4 TRIM23 TRIM27 TRIM55 TRIM63 TRIP6 WWOX ZNF765 ZNF792 ZRANB1
Entrez ID		222484	51545
HPRD ID		10042	15858
Ensembl ID		ENSG00000139517	ENSG00000171425
Uniprot IDs		Q8N448	Q9P0T4
PDB IDs		2VWR 5DIN 5E11 5E1Y 5E21 5E22
Enriched GO Terms of Interacting Partners?
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