NAGK and DYNC1I1

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		NAGK	DYNC1I1
Description		N-acetylglucosamine kinase	dynein cytoplasmic 1 intermediate chain 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Extracellular Exosome	Kinetochore Spindle Pole Nucleus Cytoplasm Cytosol Cytoplasmic Dynein Complex Microtubule Vesicle Cytoplasmic Ribonucleoprotein Granule Perinuclear Region Of Cytoplasm Recycling Endosome
	Molecular Function	Protein Binding ATP Binding N-acetylglucosamine Kinase Activity	Cytoskeletal Motor Activity Microtubule Motor Activity Protein Binding Microtubule Binding Spectrin Binding Dynein Light Chain Binding Dynein Heavy Chain Binding
	Biological Process	N-acetylglucosamine Metabolic Process N-acetylmannosamine Metabolic Process N-acetylneuraminate Catabolic Process Carbohydrate Phosphorylation	Microtubule-based Movement Transport Along Microtubule Vesicle Transport Along Microtubule
Pathways		Synthesis of UDP-N-acetyl-glucosamine	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase HCMV Early Events Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation
Drugs		N-Acetylglucosamine
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Erythema nodosum in inflammatory bowel disease ( 24487271)	Dementia and core Alzheimer's disease neuropathologic changes ( 25188341) Heel bone mineral density ( 30598549) Hip circumference adjusted for BMI ( 28552196) Immune reponse to smallpox (secreted IL-10) ( 22610502) Knee osteoarthritis ( 27696742) Multisite chronic pain ( 33830993 31194737) Obesity-related traits ( 23251661) Oily fish consumption ( 32066663) Pork consumption ( 32066663) Refractive error ( 32231278)
Interacting Genes		34 interacting genes: ACTR10 ANKRD1 CCDC158 CDKN2C CEP43 DACH1 DCP2 DYNC1I1 ELP4 GNPNAT1 LACTB2 LENG1 LMO1 LNX1 LNX2 LSM8 MEOX1 MTHFD2 NTAQ1 PJA1 PKM PPHLN1 REL SDCBP SF3B3 SMAD2 SMAD9 SPRED1 SRPK2 STK16 SYNE4 TCF12 TNNT1 WDR82	39 interacting genes: ANXA7 BICD1 CADM4 CDKN1A DDX19B DNM2 DYNLL1 DYNLL2 DYNLRB1 DYNLT1 DYNLT3 EMILIN1 FAM110A FAM83D FBP1 GRB7 GSK3B KAT7 KLC2 MCC MCM7 NAGK NDUFV2 NPTX2 NUDT21 NUP214 PIN1 RAP1GAP RCC1 RUNDC3B SEM1 SERPINE1 SMN1 STAU1 TAOK1 TK1 TRIM58 WDCP ZKSCAN1
Entrez ID		55577	1780
HPRD ID		08441	04798
Ensembl ID		ENSG00000124357	ENSG00000158560
Uniprot IDs		A0A384N6G7 C9JEV6 Q9UJ70	A4D1I7 O14576 Q8N542
PDB IDs		2CH5 2CH6
Enriched GO Terms of Interacting Partners?
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