LNX2 and PTCD3

Number of citations of the paper that reports this interaction (PubMedID 29892012)
25

Data Source:
BioGRID (two hybrid)

		LNX2	PTCD3
Description		ligand of numb-protein X 2	pentatricopeptide repeat domain 3
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GO Annotations	Cellular Component		Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Cytosol Ribosome Plasma Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding PDZ Domain Binding Identical Protein Binding Metal Ion Binding	RNA Binding Protein Binding RRNA Binding Ribosomal Small Subunit Binding
	Biological Process	Protein Ubiquitination	Regulation Of Translation Mitochondrial Translation
Pathways			Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Body mass index ( 26426971 28892062) Large B-cell lymphoma ( 21471979) Mean platelet volume ( 32888494 27863252) Night sleep phenotypes ( 27126917) Platelet distribution width ( 32888494 27863252) Response to cytadine analogues (cytosine arabinoside) ( 24483146)	Diastolic blood pressure ( 27841878) Facial emotion recognition (sad faces) ( 28608620) Pulse pressure ( 27841878) Response to methylphenidate treatment in attention-deficit/hyperactivity disorder (blood pressure) ( 21130132) Systolic blood pressure ( 27841878)
Interacting Genes		90 interacting genes: ATP5F1B C10orf88 CABP4 CBX4 CCT3 CDK2 CDK4 CDKN2C CRK CXADR DDA1 DRAP1 EAF2 FANCG FHL3 GADD45A GJD2 GLRX3 GRAP2 GRB2 IGSF5 IL16 INMT IP6K2 L3MBTL2 LGALS14 LNX1 LRRC8E MAP2K5 MAPK9 MCM7 MDGA1 MLX MRFAP1L1 MSRB3 MYLIP NAGK NMD3 NOTCH1 NTAQ1 NUDT14 NUMB OPTN PAN3 PARVG PDZRN3 PDZRN4 PEG10 PHYKPL PIK3R1 PIK3R3 PKDREJ POLR1C PPIH PPIL1 PSMD5 PSMF1 PTCD3 RAB6B RBM17 RLIM RNF138 ROPN1 RPA2 SCLY SCNM1 SFN SH3GLB2 SHISA2 SHTN1 SMARCB1 SRSF11 TAB1 TBC1D7 TCL1A TIFA TRAF1 TRAF2 TUBB UBE2D2 UBE2H UBE2I UBE2T UBE2Z USP2 VTN YJU2 ZNF148 ZNF410 ZNF581	22 interacting genes: ATF4 BIRC7 HGS IFITM2 LNX2 LUC7L2 MIR128-2 MIR18B MIR200B MIR200C MIR205 MIR21 MIR214 MIR34B MIR34C MIR363 MIRLET7A2 MIRLET7F2 MIRLET7G MT-RNR1 TBPL1 UBE3A
Entrez ID		222484	55037
HPRD ID		10042	08631
Ensembl ID		ENSG00000139517	ENSG00000132300
Uniprot IDs		Q8N448	Q96EY7
PDB IDs		2VWR 5DIN 5E11 5E1Y 5E21 5E22	3J9M 6NU2 6NU3 6RW4 6RW5 6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7A5F 7A5G 7A5I 7A5K
Enriched GO Terms of Interacting Partners?
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