NAGK and ELP4

		NAGK	ELP4
Description		N-acetylglucosamine kinase	elongator acetyltransferase complex subunit 4
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Extracellular Exosome	Nucleoplasm Cytoplasm Transcription Elongation Factor Complex Elongator Holoenzyme Complex
	Molecular Function	Protein Binding ATP Binding N-acetylglucosamine Kinase Activity	RNA Polymerase II Complex Binding Protein Binding Phosphorylase Kinase Regulator Activity
	Biological Process	N-acetylglucosamine Metabolic Process N-acetylmannosamine Metabolic Process N-acetylneuraminate Catabolic Process Carbohydrate Phosphorylation	TRNA Wobble Uridine Modification Regulation Of Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter Regulation Of Catalytic Activity
Pathways		Synthesis of UDP-N-acetyl-glucosamine	HATs acetylate histones
Drugs		N-Acetylglucosamine
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Erythema nodosum in inflammatory bowel disease ( 24487271)	Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Depression ( 29700475) Glaucoma ( 25027321) Mental health study participation (completed survey) ( 31263887) Optic disc area ( 25631615) Optic disc size ( 31809533) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		34 interacting genes: ACTR10 ANKRD1 CCDC158 CDKN2C CEP43 DACH1 DCP2 DYNC1I1 ELP4 GNPNAT1 LACTB2 LENG1 LMO1 LNX1 LNX2 LSM8 MEOX1 MTHFD2 NTAQ1 PJA1 PKM PPHLN1 REL SDCBP SF3B3 SMAD2 SMAD9 SPRED1 SRPK2 STK16 SYNE4 TCF12 TNNT1 WDR82	6 interacting genes: ELP3 FDFT1 HINFP NAGK PAMR1 PPP1CC
Entrez ID		55577	26610
HPRD ID		08441	07377
Ensembl ID		ENSG00000124357	ENSG00000109911
Uniprot IDs		A0A384N6G7 C9JEV6 Q9UJ70	G5E9D4 Q96EB1
PDB IDs		2CH5 2CH6
Enriched GO Terms of Interacting Partners?
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