SSNA1 and TBC1D7

Data Source:
BioGRID (two hybrid)

		SSNA1	TBC1D7
Description		SS nuclear autoantigen 1	TBC1 domain family member 7
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Centrosome Cytosol Ciliary Basal Body	Cytosol Cytoplasmic Vesicle Ciliary Basal Body
	Molecular Function	Protein Binding Identical Protein Binding	GTPase Activator Activity Protein Binding Small GTPase Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Intraciliary Transport Ciliary Receptor Clustering Involved In Smoothened Signaling Pathway Ciliary Basal Body-plasma Membrane Docking	Positive Regulation Of Protein Ubiquitination Negative Regulation Of TOR Signaling Positive Regulation Of GTPase Activity Response To Growth Factor Activation Of GTPase Activity Negative Regulation Of Cilium Assembly
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2	TBC/RABGAPs
Drugs
Diseases
GWAS			Migraine ( 23793025) Migraine without aura ( 23793025)
Interacting Genes		12 interacting genes: CDC37 EHHADH LNX1 NTAQ1 PICK1 PSMC5 RNF4 SDCBP SPAST TBC1D7 TCEANC TXN2	30 interacting genes: AKT1 ALOX5 APP BAG4 BLZF1 GABARAPL1 HOOK1 IKBKG INCA1 KEAP1 KRT19 KRT35 LDOC1 LNX2 LZTS1 LZTS2 MAP1LC3A MIPOL1 MMADHC NEDD4 NEDD4L PICK1 RPGRIP1 SH3GLB2 SSNA1 TRAF4 TRIM62 TSC1 XPA YWHAZ
Entrez ID		8636	51256
HPRD ID		10251	18165
Ensembl ID		ENSG00000176101	ENSG00000145979
Uniprot IDs		A0A024R8G6 O43805	A0A024QZX0 A0A024R011 Q5JPB9 Q9P0N9 U3KPY5
PDB IDs			3QWL 4Z6Y 5EJC 5ULO
Enriched GO Terms of Interacting Partners?
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