SCD and CYB5A

Number of citations of the paper that reports this interaction (PubMedID 6102994)
11

Data Source:
HPRD (in vitro)

		SCD	CYB5A
Description		stearoyl-CoA desaturase	cytochrome b5 type A
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GO Annotations	Cellular Component	Nucleolus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane	Mitochondrial Outer Membrane Endoplasmic Reticulum Membrane Cytosol Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Stearoyl-CoA 9-desaturase Activity Iron Ion Binding Protein Binding Oxidoreductase Activity Palmitoyl-CoA 9-desaturase Activity	Cytochrome-c Oxidase Activity Enzyme Binding Heme Binding Metal Ion Binding
	Biological Process	Unsaturated Fatty Acid Biosynthetic Process Regulation Of Cholesterol Biosynthetic Process Fatty-acyl-CoA Biosynthetic Process Oxidation-reduction Process Response To Fatty Acid Positive Regulation Of Cold-induced Thermogenesis	L-ascorbic Acid Metabolic Process Electron Transport Chain Response To Cadmium Ion Proton Transmembrane Transport
Pathways		Activation of gene expression by SREBF (SREBP) Fatty acyl-CoA biosynthesis NR1H2 & NR1H3 regulate gene expression linked to lipogenesis	Vitamin C (ascorbate) metabolism
Drugs			Dimethyl Propionate Ester Heme
Diseases			Methemoglobinemia
GWAS		Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Glycerophospholipid levels ( 26068415) Macular thickness ( 30535121) Metabolic traits ( 21886157) Metabolite levels ( 23823483) Palmitic acid (16:0) levels ( 23362303) Palmitoleic acid (16:1n-7) levels ( 23362303) Vaccenic acid (18:1n-7) levels ( 28298293) White blood cell count (basophil) ( 27863252)	Blood protein levels ( 30072576)
Interacting Genes		4 interacting genes: APP CYB5A NEDD4L UBC	14 interacting genes: CYB5R3 CYCS CYP17A1 CYP1A1 CYP1A2 CYP2A6 CYP2D6 CYP2E1 CYP2W1 CYP3A4 CYP4A11 POR SCD UGT1A4
Entrez ID		6319	1528
HPRD ID		04941	08941
Ensembl ID		ENSG00000099194	ENSG00000166347
Uniprot IDs		O00767	A0A384ME44 P00167
PDB IDs		4ZYO	2I96
Enriched GO Terms of Interacting Partners?
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