CYP2W1 and CYB5A

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		CYP2W1	CYB5A
Description		cytochrome P450 family 2 subfamily W member 1	cytochrome b5 type A
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Plasma Membrane Cell Surface Intracellular Membrane-bounded Organelle	Mitochondrial Outer Membrane Endoplasmic Reticulum Membrane Cytosol Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Iron Ion Binding Steroid Hydroxylase Activity Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, Reduced Flavin Or Flavoprotein As One Donor, And Incorporation Of One Atom Of Oxygen Heme Binding	Cytochrome-c Oxidase Activity Enzyme Binding Heme Binding Metal Ion Binding
	Biological Process	Organic Acid Metabolic Process Xenobiotic Metabolic Process Exogenous Drug Catabolic Process Aflatoxin Metabolic Process Oxidation-reduction Process	L-ascorbic Acid Metabolic Process Electron Transport Chain Response To Cadmium Ion Proton Transmembrane Transport
Pathways		Miscellaneous substrates Xenobiotics	Vitamin C (ascorbate) metabolism
Drugs			Dimethyl Propionate Ester Heme
Diseases			Methemoglobinemia
GWAS		Bronchopulmonary dysplasia ( 23897914) Insomnia symptoms (never/rarely vs. sometimes/usually) ( 30804566) Insomnia symptoms (never/rarely vs. usually) ( 30804566)	Blood protein levels ( 30072576)
Interacting Genes		2 interacting genes: CYB5A ZBTB26	14 interacting genes: CYB5R3 CYCS CYP17A1 CYP1A1 CYP1A2 CYP2A6 CYP2D6 CYP2E1 CYP2W1 CYP3A4 CYP4A11 POR SCD UGT1A4
Entrez ID		54905	1528
HPRD ID		07901	08941
Ensembl ID		ENSG00000073067	ENSG00000166347
Uniprot IDs		Q8TAV3	A0A384ME44 P00167
PDB IDs			2I96
Enriched GO Terms of Interacting Partners?
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