GAS1 and CYB5R3

		GAS1	CYB5R3
Description		growth arrest specific 1	cytochrome b5 reductase 3
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Anchored Component Of Plasma Membrane	Extracellular Region Cytoplasm Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Hemoglobin Complex Membrane Azurophil Granule Lumen
	Molecular Function	Protein Binding	Cytochrome-b5 Reductase Activity, Acting On NAD(P)H Protein Binding AMP Binding ADP Binding NAD Binding FAD Binding
	Biological Process	Cell Cycle Arrest Regulation Of Smoothened Signaling Pathway Negative Regulation Of Protein Processing Cellular Response To Vascular Endothelial Growth Factor Stimulus Regulation Of Apoptotic Process Cell Fate Commitment Negative Regulation Of Mitotic Cell Cycle Developmental Growth Regulation Of ER To Golgi Vesicle-mediated Transport	Cholesterol Biosynthetic Process Xenobiotic Metabolic Process Blood Circulation L-ascorbic Acid Metabolic Process Neutrophil Degranulation Oxidation-reduction Process
Pathways		Ligand-receptor interactions Activation of SMO	Vitamin C (ascorbate) metabolism Phase I - Functionalization of compounds Neutrophil degranulation
Drugs			NADH Flavin adenine dinucleotide Copper
Diseases			Methemoglobinemia
GWAS		Blood protein levels ( 30072576) Borderline personality disorder ( 28632202) Heel bone mineral density ( 30598549) Insulin resistance/response ( 21901158) Lung function in never smokers (high FEV1 vs average FEV1) ( 26423011) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)	Initial pursuit acceleration ( 29064472)
Interacting Genes		5 interacting genes: BIRC2 CYB5R3 DLK1 ERRFI1 SHH	11 interacting genes: ARSA CYB5A CYCS GAS1 HBG2 L3MBTL2 RPS6KB1 SBF1 SPP1 TUBGCP6 XPNPEP3
Entrez ID		2619	1727
HPRD ID		00747	08942
Ensembl ID		ENSG00000180447	ENSG00000100243
Uniprot IDs		P54826	P00387
PDB IDs			1M91 1UMK
Enriched GO Terms of Interacting Partners?
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