CYP2E1 and CYB5A

Number of citations of the paper that reports this interaction (PubMedID 15680923)
23

Data Source:
BioGRID (pull down)

		CYP2E1	CYB5A
Description		cytochrome P450 family 2 subfamily E member 1	cytochrome b5 type A
Image
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Mitochondrial Inner Membrane Endoplasmic Reticulum Membrane Intrinsic Component Of Endoplasmic Reticulum Membrane Intracellular Membrane-bounded Organelle	Mitochondrial Outer Membrane Endoplasmic Reticulum Membrane Cytosol Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Monooxygenase Activity Iron Ion Binding Arachidonic Acid Epoxygenase Activity Steroid Hydroxylase Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, NAD(P)H As One Donor, And Incorporation Of One Atom Of Oxygen Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, Reduced Flavin Or Flavoprotein As One Donor, And Incorporation Of One Atom Of Oxygen 4-nitrophenol 2-monooxygenase Activity Oxygen Binding Enzyme Binding Heme Binding Hsp70 Protein Binding Hsp90 Protein Binding Aromatase Activity	Cytochrome-c Oxidase Activity Enzyme Binding Heme Binding Metal Ion Binding
	Biological Process	Lipid Hydroxylation Organic Acid Metabolic Process Triglyceride Metabolic Process Xenobiotic Metabolic Process Steroid Metabolic Process Response To Bacterium Response To Ozone Response To Organonitrogen Compound Monoterpenoid Metabolic Process Drug Metabolic Process Carbon Tetrachloride Metabolic Process Benzene Metabolic Process 4-nitrophenol Metabolic Process Epoxygenase P450 Pathway Halogenated Hydrocarbon Metabolic Process Exogenous Drug Catabolic Process Long-chain Fatty Acid Biosynthetic Process Response To Ethanol Heterocycle Metabolic Process Oxidation-reduction Process	L-ascorbic Acid Metabolic Process Electron Transport Chain Response To Cadmium Ion Proton Transmembrane Transport
Pathways		Xenobiotics CYP2E1 reactions Biosynthesis of maresin-like SPMs	Vitamin C (ascorbate) metabolism
Drugs		Diacerein	Dimethyl Propionate Ester Heme
Diseases			Methemoglobinemia
GWAS		Childhood body mass index ( 31752434) Coffee consumption ( 31046077) Gout ( 22179738) Obesity-related traits ( 23251661) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)	Blood protein levels ( 30072576)
Interacting Genes		15 interacting genes: ABCA5 AGXT2 AMFR CLU CYB5A ECHS1 FANCG GATM LAMC3 MAFG NMI POR PTN RPL13A STUB1	14 interacting genes: CYB5R3 CYCS CYP17A1 CYP1A1 CYP1A2 CYP2A6 CYP2D6 CYP2E1 CYP2W1 CYP3A4 CYP4A11 POR SCD UGT1A4
Entrez ID		1571	1528
HPRD ID		11813	08941
Ensembl ID		ENSG00000130649	ENSG00000166347
Uniprot IDs		P05181	A0A384ME44 P00167
PDB IDs		3E4E 3E6I 3GPH 3KOH 3LC4 3T3Z	2I96
Enriched GO Terms of Interacting Partners?
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