| Novel |
GDF11
|
growth differentiation factor 11 |
|
|
|
| Novel |
NEUROD4
|
neuronal differentiation 4 |
|
|
|
| Novel |
ORMDL2
|
ORMDL sphingolipid biosynthesis regulator 2 |
- Sphingolipid de novo biosynthesis
|
|
|
| Novel |
PPP1R1A
|
protein phosphatase 1 regulatory inhibitor subunit 1A |
|
|
|
| Novel |
SUOX
|
sulfite oxidase |
- Sulfide oxidation to sulfate
|
- {[2-Amino-4-oxo-6,7-di(sulfanyl-κS)-3,5,5a,8,9a,10-hexahydro-4H-pyrano[3,2-g]pteridin-8-yl]methyl dihydrogenato(2-) phosphate}(dioxo)sulfanylmolybdenum
|
|
| Novel |
TBATA
|
thymus, brain and testes associated |
|
|
|
|
ADRB2
|
adrenoceptor beta 2 |
- Adrenoceptors
- G alpha (s) signalling events
- Ub-specific processing proteases
- Cargo recognition for clathrin-mediated endocytosis
- Clathrin-mediated endocytosis
|
- Spermine
- Amphetamine
- Betaxolol
- Bethanidine
- Isoetharine
- Cabergoline
- Metoprolol
- Metoprolol
- Olanzapine
- Atenolol
- Norepinephrine
- Timolol
- Phenylpropanolamine
- Dipivefrin
- Sotalol
- Carteolol
- Nortriptyline
- Propranolol
- Labetalol
- Bisoprolol
- Epinephrine
- Paroxetine
- Trimipramine
- Cryptenamine
- Orciprenaline
- Dobutamine
- Pseudoephedrine
- Alprenolol
- Ritodrine
- Ritodrine
- Terbutaline
- Bitolterol
- Phenoxybenzamine
- Salmeterol
- Pindolol
- Formoterol
- Salbutamol
- Ergoloid mesylate
- Isoprenaline
- Arbutamine
- Amiodarone
- Carvedilol
- Desipramine
- Propafenone
- Acebutolol
- Nadolol
- Levobunolol
- Metipranolol
- Aripiprazole
- Arformoterol
- Fenoterol
- Pirbuterol
- Bevantolol
- Penbutolol
- Ephedra sinica root
- Ephedrine
- Mephentermine
- Procaterol
- Clenbuterol
- Bambuterol
- Oxprenolol
- Putrescine
- Spermidine
- Celiprolol
- Nebivolol
- Indacaterol
- Bedoradrine
- NCX 950
- Asenapine
- Droxidopa
- Bufuralol
- Protokylol
- (S)-carazolol
- Bopindolol
- Bupranolol
- Befunolol
- Olodaterol
- Vilanterol
- Viloxazine
- Arotinolol
- Doxofylline
- Racepinephrine
- Dihydroergocornine
- DL-Methylephedrine
- Etafedrine
- Tulobuterol
- Levosalbutamol
- Dihydroergocristine
- Methoxyphenamine
|
|
|
AIRIM
|
AFG2 interacting ribosome maturation factor |
|
|
|
|
AP2S1
|
adaptor related protein complex 2 subunit sigma 1 |
- Nef Mediated CD4 Down-regulation
- Retrograde neurotrophin signalling
- Retrograde neurotrophin signalling
- Nef Mediated CD8 Down-regulation
- MHC class II antigen presentation
- EPH-ephrin mediated repulsion of cells
- Recycling pathway of L1
- Recycling pathway of L1
- WNT5A-dependent internalization of FZD4
- WNT5A-dependent internalization of FZD2, FZD5 and ROR2
- Cargo recognition for clathrin-mediated endocytosis
- Clathrin-mediated endocytosis
- VLDLR internalisation and degradation
- LDL clearance
- Potential therapeutics for SARS
|
|
|
|
APP
|
amyloid beta precursor protein |
- Platelet degranulation
- ECM proteoglycans
- Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
- G alpha (q) signalling events
- G alpha (i) signalling events
- Lysosome Vesicle Biogenesis
- Formyl peptide receptors bind formyl peptides and many other ligands
- TAK1-dependent IKK and NF-kappa-B activation
- The NLRP3 inflammasome
- Advanced glycosylation endproduct receptor signaling
- Advanced glycosylation endproduct receptor signaling
- Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
- Post-translational protein phosphorylation
- TRAF6 mediated NF-kB activation
- Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
- Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
- Purinergic signaling in leishmaniasis infection
- Amyloid fiber formation
|
- Deferoxamine
- Aluminium
- Zinc
- L-methionine (R)-S-oxide
- Resveratrol
- Tromethamine
- Phenserine
- Tetrathiomolybdate
- CAD106
- Mito-4509
- Edonerpic
- Dimercaprol
- Copper
- Florbetaben (18F)
- Florbetapir (18F)
- Flutemetamol (18F)
- Gantenerumab
- Aducanumab
- Zinc acetate
- Aluminium phosphate
- Aluminum acetate
- Zinc chloride
- Zinc sulfate, unspecified form
- Lecanemab
|
|
|
ARL6IP4
|
ARF like GTPase 6 interacting protein 4 |
|
|
|
|
BIRC6
|
baculoviral IAP repeat containing 6 |
- ALK mutants bind TKIs
- Signaling by ALK fusions and activated point mutants
|
|
|
|
CLEC9A
|
C-type lectin domain containing 9A |
|
|
|
|
ERBB3
|
erb-b2 receptor tyrosine kinase 3 |
|
|
- Type I diabetes mellitus
- Lethal congenital contractural syndrome (LCCS)
|
|
ERBB4
|
erb-b2 receptor tyrosine kinase 4 |
|
- Afatinib
- Fostamatinib
- Brigatinib
- Zanubrutinib
|
|
|
IRS4
|
insulin receptor substrate 4 |
- IRS-related events triggered by IGF1R
|
|
|
|
KDM3B
|
lysine demethylase 3B |
- HDMs demethylate histones
|
|
|
|
LEPR
|
leptin receptor |
|
|
|
|
LZTS2
|
leucine zipper tumor suppressor 2 |
|
|
|
|
MAGEL2
|
MAGE family member L2 |
|
|
|