Search Results for: GRPEL1

14 interactions involving GRPEL1 - GrpE like 1, mitochondrial found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases
Novel Symbol Description Pathways Hide Drugs Hide Diseases Hide
Novel DSP desmoplakin
  • Apoptotic cleavage of cell adhesion proteins
  • Neutrophil degranulation
  • Keratinization
  • Formation of the cornified envelope
  • RND3 GTPase cycle
  • RND1 GTPase cycle
  • Zinc
  • Artenimol
  • Zinc acetate
  • Striate palmoplantar keratoderma
  • Skin fragility-woolly hair syndrome
  • Arrhythmogenic right ventricular cardiomyopathy (ARVC)
  • Naxos disease and Carvajal syndrome
  • Epidermolysis bullosa simplex, including: Epidermolysis bullosa simplex, Dowling-Meara type (EBS-DM); Epidermolysis bullosa simplex, Koebner type (EBS-K); Epidermolysis bullosa simplex, Weber-Cockayne type (EBS-WC); Epidermolysis bullosa simplex with mottled pigmentation (EBS-MP); Epidermolysis bullosa simplex with migratory circinate erythema; Epidermolysis bullosa simplex, recessive; Epidermolysis bullosa, lethal acantholytic
Novel FAM184B family with sequence similarity 184 member B
Novel FGFBP2 fibroblast growth factor binding protein 2
  • FGFR2b ligand binding and activation
Novel MED28 mediator complex subunit 28
  • PPARA activates gene expression
  • Transcriptional regulation of white adipocyte differentiation
  • Transcriptional regulation of white adipocyte differentiation
  • RSV-host interactions
Novel NKX3-2 NK3 homeobox 2
  • Regulation of RUNX2 expression and activity
  • Spondylo-megaepiphyseal-metaphyseal dysplasia
Novel SFTPB surfactant protein B
  • Surfactant metabolism
  • Defective pro-SFTPB causes SMDP1 and RDS
  • Defective CSF2RB causes SMDP5
  • Defective CSF2RA causes SMDP4
  • Pulmonary surfactant metabolism dysfunction (SMDP)
Novel XYLB xylulokinase
  • Formation of xylulose-5-phosphate
CCDC57 coiled-coil domain containing 57
ERCC6 ERCC excision repair 6, chromatin remodeling factor
  • ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
  • B-WICH complex positively regulates rRNA expression
  • Formation of TC-NER Pre-Incision Complex
  • Transcription-Coupled Nucleotide Excision Repair (TC-NER)
  • Dual incision in TC-NER
  • Gap-filling DNA repair synthesis and ligation in TC-NER
  • RNA Polymerase I Transcription Initiation
  • Macular degeneration, including: Age-related macular degeneration (ARMD); Patterned dystrophy of retinal pigment epithelium (PDREP); Retinal macular dystrophy 2 (MCDR2); X-linked atrophic macular degeneration (MDXLA)
  • Cockayne syndrome
  • Disorders of nucleotide excision repair, including: Xeroderma pigmentosum (XP); Cockayne syndrome (CS); UV-sensitive syndrome (UVS); Trichothiodystrophy (TTD); Cerebro-oculo-facio-skeletal syndrome (COFS); XFE progeroid syndrome
GALT galactose-1-phosphate uridylyltransferase
  • Defective GALT can cause GALCT
  • Galactose catabolism
  • Galactosemia
ISG15 ISG15 ubiquitin like modifier
  • ISG15 antiviral mechanism
  • NS1 Mediated Effects on Host Pathways
  • DDX58/IFIH1-mediated induction of interferon-alpha/beta
  • Termination of translesion DNA synthesis
  • Interferon alpha/beta signaling
  • Negative regulators of DDX58/IFIH1 signaling
  • SARS-CoV-2 activates/modulates innate and adaptive immune responses
  • RSV-host interactions
  • PKR-mediated signaling
  • Modulation of host responses by IFN-stimulated genes
POLR1C RNA polymerase I and III subunit C
  • Cytosolic sensors of pathogen-associated DNA
  • NoRC negatively regulates rRNA expression
  • B-WICH complex positively regulates rRNA expression
  • RNA Polymerase I Transcription Initiation
  • RNA Polymerase I Transcription Initiation
  • RNA Polymerase I Promoter Escape
  • RNA Polymerase III Chain Elongation
  • RNA Polymerase I Transcription Termination
  • RNA Polymerase III Transcription Termination
  • RNA Polymerase III Abortive And Retractive Initiation
  • RNA Polymerase III Transcription Initiation From Type 1 Promoter
  • RNA Polymerase III Transcription Initiation From Type 1 Promoter
  • RNA Polymerase III Transcription Initiation From Type 2 Promoter
  • RNA Polymerase III Transcription Initiation From Type 2 Promoter
  • RNA Polymerase III Transcription Initiation From Type 3 Promoter
  • RNA Polymerase III Transcription Initiation From Type 3 Promoter
  • Treacher Collins syndrome
SPG21 SPG21 abhydrolase domain containing, maspardin
  • Hereditary spastic paraplegia (SPG)
WBP2 WW domain binding protein 2

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