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GRPEL1 and FAM184B
GRPEL1
FAM184B
Description
GrpE like 1, mitochondrial
family with sequence similarity 184 member B
Image
No pdb structure
GO Annotations
Cellular Component
PAM Complex, Tim23 Associated Import Motor
Nucleoplasm
Mitochondrion
Mitochondrial Inner Membrane
TIM23 Mitochondrial Import Inner Membrane Translocase Complex
Mitochondrial Matrix
Molecular Function
Adenyl-nucleotide Exchange Factor Activity
Protein Binding
Identical Protein Binding
Protein Homodimerization Activity
Unfolded Protein Binding
Protein-folding Chaperone Binding
Biological Process
Protein Folding
Intracellular Protein Transport
Protein Import Into Mitochondrial Matrix
Pathways
Mitochondrial protein import
Drugs
Diseases
GWAS
Eosinophil percentage of white cells (
32888494
)
Height (
25429064
28552196
)
Hip circumference adjusted for BMI (
34021172
)
Platelet count (
32888494
)
Plateletcrit (
32888494
)
Interacting Genes
7 interacting genes:
CCDC57
ERCC6
GALT
ISG15
POLR1C
SPG21
WBP2
Entrez ID
80273
27146
HPRD ID
07550
19526
Ensembl ID
ENSG00000109519
ENSG00000047662
Uniprot IDs
Q9HAV7
Q9ULE4
PDB IDs
9BLS
9BLT
9BLU
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Epithelial Cell Apoptotic Process
Pancreas Development
Negative Regulation Of ATF6-mediated Unfolded Protein Response
Multicellular Organismal-level Water Homeostasis
Proteasome Binding
Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of ERAD Pathway
ER Overload Response
Endoplasmic Reticulum Calcium Ion Homeostasis
Protein Carrier Chaperone
Renal Water Homeostasis
Regulation Of ERAD Pathway
Olfactory Behavior
Negative Regulation Of Endoplasmic Reticulum Unfolded Protein Response
Regulation Of ATF6-mediated Unfolded Protein Response
Chemosensory Behavior
Negative Regulation Of Type B Pancreatic Cell Apoptotic Process
PAM Complex, Tim23 Associated Import Motor
TIM23 Mitochondrial Import Inner Membrane Translocase Complex
Adenyl-nucleotide Exchange Factor Activity
Protein Import Into Mitochondrial Matrix
Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway
Regulation Of Endoplasmic Reticulum Unfolded Protein Response
ER-nucleus Signaling Pathway
Positive Regulation Of Response To Endoplasmic Reticulum Stress
Protein Localization To Mitochondrion
Negative Regulation Of Response To Endoplasmic Reticulum Stress
Regulation Of Epithelial Cell Apoptotic Process
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Tagcloud (Intersection)
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