VPS11 - New-wiki

Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
RDX	radixin	Recycling pathway of L1 Recycling pathway of L1 Sensory processing of sound by inner hair cells of the cochlea Sensory processing of sound by outer hair cells of the cochlea	1D-myo-inositol 1,4,5-trisphosphate
RILP	Rab interacting lysosomal protein	MHC class II antigen presentation
RNF181	ring finger protein 181	E3 ubiquitin ligases ubiquitinate target proteins
STX1A	syntaxin 1A	Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle Insulin processing Regulation of insulin secretion Other interleukin signaling Toxicity of botulinum toxin type C (botC) LGI-ADAM interactions Neurexins and neuroligins GABA synthesis, release, reuptake and degradation Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Sensory processing of sound by inner hair cells of the cochlea
STX6	syntaxin 6	Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network
STX7	syntaxin 7
STX8	syntaxin 8
TFAP2B	transcription factor AP-2 beta	SUMOylation of transcription factors Negative regulation of activity of TFAP2 (AP-2) family transcription factors Negative regulation of activity of TFAP2 (AP-2) family transcription factors Activation of the TFAP2 (AP-2) family of transcription factors TFAP2 (AP-2) family regulates transcription of growth factors and their receptors Specification of the neural plate border Specification of the neural plate border		Char syndrome
TRIM32	tripartite motif containing 32	Regulation of innate immune responses to cytosolic DNA Antigen processing: Ubiquitination & Proteasome degradation		Bardet-Biedl syndrome (BBS)
TSG101	tumor susceptibility 101	Budding and maturation of HIV virion Membrane binding and targetting of GAG proteins Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy
UBE2D2	ubiquitin conjugating enzyme E2 D2	Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha TICAM1, RIP1-mediated IKK complex recruitment Downstream TCR signaling FCERI mediated NF-kB activation PINK1-PRKN Mediated Mitophagy Regulation of TNFR1 signaling CLEC7A (Dectin-1) signaling Synthesis of active ubiquitin: roles of E1 and E2 enzymes E3 ubiquitin ligases ubiquitinate target proteins Neddylation Peroxisomal protein import Negative regulators of DDX58/IFIH1 signaling IKK complex recruitment mediated by RIP1 Inactivation of CSF3 (G-CSF) signaling Antigen processing: Ubiquitination & Proteasome degradation Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA	(R,R)-2,3-Butanediol
UBE2L3	ubiquitin conjugating enzyme E2 L3	PINK1-PRKN Mediated Mitophagy Regulation of TNFR1 signaling Regulation of necroptotic cell death Synthesis of active ubiquitin: roles of E1 and E2 enzymes E3 ubiquitin ligases ubiquitinate target proteins Antigen processing: Ubiquitination & Proteasome degradation
UBE2U	ubiquitin conjugating enzyme E2 U	Antigen processing: Ubiquitination & Proteasome degradation
UVRAG	UV radiation resistance associated	Macroautophagy Translation of Replicase and Assembly of the Replication Transcription Complex Translation of Replicase and Assembly of the Replication Transcription Complex SARS-CoV-2 modulates autophagy
VPS16	VPS16 core subunit of CORVET and HOPS complexes	SARS-CoV-2 modulates autophagy
VPS18	VPS18 core subunit of CORVET and HOPS complexes	SARS-CoV-2 modulates autophagy
VPS33A	VPS33A core subunit of CORVET and HOPS complexes	SARS-CoV-2 modulates autophagy
VPS45	vacuolar protein sorting 45 homolog	Intra-Golgi traffic SARS-CoV-2 modulates autophagy Factors involved in megakaryocyte development and platelet production

Search Results for: VPS11