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HSPB1
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heat shock protein family B (small) member 1 |
- VEGFA-VEGFR2 Pathway
- AUF1 (hnRNP D0) binds and destabilizes mRNA
- MAPK6/MAPK4 signaling
- Extra-nuclear estrogen signaling
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- Apatorsen
- Artenimol
- Phenethyl Isothiocyanate
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- Distal hereditary motor neuropathies (dHMN)
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LSM2
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LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated |
- mRNA decay by 5' to 3' exoribonuclease
- mRNA decay by 5' to 3' exoribonuclease
- mRNA Splicing - Major Pathway
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PIH1D2
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PIH1 domain containing 2 |
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PLCD1
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phospholipase C delta 1 |
- Synthesis of IP3 and IP4 in the cytosol
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- 1D-myo-inositol 1,4,5-trisphosphate
- Inositol 2,4,5-trisphosphate
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PLD1
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phospholipase D1 |
- Synthesis of PG
- Synthesis of PA
- Role of phospholipids in phagocytosis
- Neutrophil degranulation
- RHOA GTPase cycle
- CDC42 GTPase cycle
- RAC1 GTPase cycle
- RHOG GTPase cycle
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- Choline
- LAX-101
- Choline salicylate
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PPP2R1B
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protein phosphatase 2 scaffold subunit Abeta |
- Inhibition of replication initiation of damaged DNA by RB1/E2F1
- Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
- PP2A-mediated dephosphorylation of key metabolic factors
- DARPP-32 events
- Degradation of beta-catenin by the destruction complex
- Beta-catenin phosphorylation cascade
- ERK/MAPK targets
- ERKs are inactivated
- MASTL Facilitates Mitotic Progression
- Separation of Sister Chromatids
- Resolution of Sister Chromatid Cohesion
- Co-stimulation by CD28
- Co-inhibition by CTLA4
- Platelet sensitization by LDL
- Disassembly of the destruction complex and recruitment of AXIN to the membrane
- Disassembly of the destruction complex and recruitment of AXIN to the membrane
- Signaling by GSK3beta mutants
- CTNNB1 S33 mutants aren't phosphorylated
- CTNNB1 S37 mutants aren't phosphorylated
- CTNNB1 S45 mutants aren't phosphorylated
- CTNNB1 T41 mutants aren't phosphorylated
- APC truncation mutants have impaired AXIN binding
- AXIN missense mutants destabilize the destruction complex
- Truncations of AMER1 destabilize the destruction complex
- RHO GTPases Activate Formins
- RAF activation
- Negative regulation of MAPK pathway
- Regulation of TP53 Degradation
- PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
- Mitotic Prometaphase
- Cyclin D associated events in G1
- Cyclin A/B1/B2 associated events during G2/M transition
- Regulation of glycolysis by fructose 2,6-bisphosphate metabolism
- EML4 and NUDC in mitotic spindle formation
- PKR-mediated signaling
- Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells
- Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells
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RAB34
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RAB34, member RAS oncogene family |
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RAB8B
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RAB8B, member RAS oncogene family |
- TBC/RABGAPs
- RAB geranylgeranylation
- RAB GEFs exchange GTP for GDP on RABs
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- Phosphoaminophosphonic acid guanylate ester
- Guanosine-5'-Diphosphate
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RALBP1
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ralA binding protein 1 |
- CDC42 GTPase cycle
- RAC1 GTPase cycle
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RALGPS1
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Ral GEF with PH domain and SH3 binding motif 1 |
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RASSF5
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Ras association domain family member 5 |
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REPS1
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RALBP1 associated Eps domain containing 1 |
- Cargo recognition for clathrin-mediated endocytosis
- Clathrin-mediated endocytosis
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RGL2
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ral guanine nucleotide dissociation stimulator like 2 |
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RGL4
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ral guanine nucleotide dissociation stimulator like 4 |
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SMAD4
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SMAD family member 4 |
- Signaling by NODAL
- Signaling by NODAL
- Signaling by Activin
- Signaling by Activin
- Signaling by BMP
- TGF-beta receptor signaling activates SMADs
- Downregulation of SMAD2/3:SMAD4 transcriptional activity
- Downregulation of SMAD2/3:SMAD4 transcriptional activity
- SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
- SMAD4 MH2 Domain Mutants in Cancer
- SMAD2/3 MH2 Domain Mutants in Cancer
- Transcriptional regulation of pluripotent stem cells
- Ub-specific processing proteases
- RUNX2 regulates bone development
- RUNX3 regulates CDKN1A transcription
- RUNX3 regulates BCL2L11 (BIM) transcription
- FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes
- FOXO-mediated transcription of cell cycle genes
- FOXO-mediated transcription of cell cycle genes
- Cardiogenesis
- SARS-CoV-1 targets host intracellular signalling and regulatory pathways
- Germ layer formation at gastrulation
- Formation of definitive endoderm
- Formation of definitive endoderm
- TGFBR3 expression
- Transcriptional regulation of brown and beige adipocyte differentiation by EBF2
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- Colorectal cancer
- Juvenile polyposis syndrome
- Hereditary hemorrhagic telangiectasia (HHT)
- Pancreatic cancer
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SNCA
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synuclein alpha |
- Amyloid fiber formation
- PKR-mediated signaling
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- Resveratrol
- Dequalinium
- Copper
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- Lewy body dementia (LBD); Dementia with Lewy bodies (DLB)
- Parkinson's disease (PD)
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YBX3
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Y-box binding protein 3 |
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