CASP10 - Wiki-Pi

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36 interactions involving CASP10 - caspase 10 found:

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Novel	Symbol	Description	Pathways Hide	Drugs Hide	Diseases Hide
	DEDD	death effector domain containing
	DEDD2	death effector domain containing 2
	DSP	desmoplakin	Apoptotic cleavage of cell adhesion proteins Neutrophil degranulation Keratinization Formation of the cornified envelope RND3 GTPase cycle RND1 GTPase cycle	Zinc Artenimol Zinc acetate	Striate palmoplantar keratoderma Skin fragility-woolly hair syndrome Arrhythmogenic right ventricular cardiomyopathy (ARVC) Naxos disease and Carvajal syndrome Epidermolysis bullosa simplex, including: Epidermolysis bullosa simplex, Dowling-Meara type (EBS-DM); Epidermolysis bullosa simplex, Koebner type (EBS-K); Epidermolysis bullosa simplex, Weber-Cockayne type (EBS-WC); Epidermolysis bullosa simplex with mottled pigmentation (EBS-MP); Epidermolysis bullosa simplex with migratory circinate erythema; Epidermolysis bullosa simplex, recessive; Epidermolysis bullosa, lethal acantholytic
	ECE2	endothelin converting enzyme 2	Peptide ligand-binding receptors
	FADD	Fas associated via death domain	Caspase activation via Death Receptors in the presence of ligand TRIF-mediated programmed cell death Regulation by c-FLIP RIPK1-mediated regulated necrosis CASP8 activity is inhibited TNFR1-induced proapoptotic signaling Regulation of TNFR1 signaling Regulation of necroptotic cell death Dimerization of procaspase-8 FasL/ CD95L signaling TRAIL signaling TLR3-mediated TICAM1-dependent programmed cell death NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 Defective RIPK1-mediated regulated necrosis
	NFKBIL1	NFKB inhibitor like 1
	OIP5	Opa interacting protein 5	Deposition of new CENPA-containing nucleosomes at the centromere
	PHF20L1	PHD finger protein 20 like 1	Formation of WDR5-containing histone-modifying complexes
	POLR2A	RNA polymerase II subunit A	Formation of RNA Pol II elongation complex Formation of the Early Elongation Complex Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex RNA Pol II CTD phosphorylation and interaction with CE during HIV infection HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome Formation of HIV-1 elongation complex containing HIV-1 Tat Formation of HIV-1 elongation complex containing HIV-1 Tat Pausing and recovery of Tat-mediated HIV elongation Abortive elongation of HIV-1 transcript in the absence of Tat Tat-mediated HIV elongation arrest and recovery Tat-mediated elongation of the HIV-1 transcript HIV elongation arrest and recovery Pausing and recovery of HIV elongation Viral Messenger RNA Synthesis MicroRNA (miRNA) biogenesis Transcriptional regulation by small RNAs PIWI-interacting RNA (piRNA) biogenesis Activation of anterior HOX genes in hindbrain development during early embryogenesis RNA Polymerase II Pre-transcription Events Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER TP53 Regulates Transcription of DNA Repair Genes FGFR2 alternative splicing RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes mRNA Capping mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Elongation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Pol II CTD phosphorylation and interaction with CE Signaling by FGFR2 IIIa TM Estrogen-dependent gene expression Inhibition of DNA recombination at telomere
	PRDX6	peroxiredoxin 6	Detoxification of Reactive Oxygen Species Neutrophil degranulation	2-(N-morpholino)ethanesulfonic acid Copper
	RB1	RB transcriptional corepressor 1	Inhibition of replication initiation of damaged DNA by RB1/E2F1 Inhibition of replication initiation of damaged DNA by RB1/E2F1 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 Condensation of Prophase Chromosomes Formation of Senescence-Associated Heterochromatin Foci (SAHF) Oncogene Induced Senescence Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes Cyclin E associated events during G1/S transition Cyclin D associated events in G1 Cyclin A:Cdk2-associated events at S phase entry RUNX2 regulates osteoblast differentiation Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) Defective translocation of RB1 mutants to the nucleus Replication of the SARS-CoV-1 genome Aberrant regulation of mitotic exit in cancer due to RB1 defects Replication of the SARS-CoV-2 genome Nuclear events stimulated by ALK signaling in cancer Positive Regulation of CDH1 Gene Transcription MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis		Chronic myeloid leukemia (CML) Breast cancer Osteosarcoma Hepatocellular carcinoma Small cell lung cancer Esophageal cancer Glioma Bladder cancer
	RIOK3	RIO kinase 3	Major pathway of rRNA processing in the nucleolus and cytosol	Fostamatinib
	RYBP	RING1 and YY1 binding protein	RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Transcriptional Regulation by E2F6
	TNFRSF1A	TNF receptor superfamily member 1A	TNFR1-induced proapoptotic signaling Regulation of TNFR1 signaling TNFR1-induced NF-kappa-B signaling pathway TNFR1-mediated ceramide production TNFs bind their physiological receptors Interleukin-10 signaling TNF signaling	6-[3-(4-Morpholinyl)Propyl]-2-(3-Nitrophenyl)-5-Thioxo-5,6,-Dihydro-7h-Thienol[2',3':4,5]Pyrrolo[1,2-C]Imidazol-7-One Tasonermin	Tumor necrosis factor receptor-associated periodic syndrome (TRAPS); Familial periodic fever
	TRAF1	TNF receptor associated factor 1	Regulation of TNFR1 signaling TNFR1-induced NF-kappa-B signaling pathway
	XIAP	X-linked inhibitor of apoptosis	Activation of caspases through apoptosome-mediated cleavage SMAC (DIABLO) binds to IAPs SMAC (DIABLO) binds to IAPs SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes SMAC, XIAP-regulated apoptotic response Deactivation of the beta-catenin transactivating complex RIPK1-mediated regulated necrosis TNFR1-induced proapoptotic signaling Regulation of TNFR1 signaling TNFR1-induced NF-kappa-B signaling pathway Regulation of necroptotic cell death Regulation of PTEN localization Regulation of PTEN stability and activity Regulation of the apoptosome activity	1-[3,3-Dimethyl-2-(2-Methylamino-Propionylamino)-Butyryl]-Pyrrolidine-2-Carboxylic Acid(1,2,3,4-Tetrahydro-Naphthalen-1-Yl)-Amide Dequalinium N-METHYLALANYL-3-METHYLVALYL-4-PHENOXY-N-(1,2,3,4-TETRAHYDRONAPHTHALEN-1-YL)PROLINAMIDE AEG35156 Terpinen-4-ol	Other well-defined immunodeficiency syndromes, including the following seven diseases: Wiskott-Aldrich syndrome; DiGeorge syndrome; Hyper-IgE syndrome; X-linked lymphoproliferative syndrome; Immunodeficiency, Polyendocrinopathy, Enteropathy, X-linked Syndrome (IPEX); Cartilage-Hair Hypoplasia; Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED)

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