CHN1 and GTF3C1

Number of citations: 0 (PubMedID 16169070)
Data Source: BioGRID (two hybrid), HPRD (two hybrid)

		CHN1	GTF3C1
Name		chimerin 1	general transcription factor IIIC subunit 1
Structure
GO Annotations	Cellular Component	Cytosol	Transcription Factor TFIIIC Complex Nucleus Nucleoplasm Nucleolus Membrane Ribonucleoprotein Complex
	Molecular Function	GTPase Activator Activity Protein Binding Zinc Ion Binding Metal Ion Binding Ephrin Receptor Binding	RNA Polymerase III General Transcription Initiation Factor Activity DNA Binding Protein Binding
	Biological Process	Signal Transduction Nervous System Development Motor Neuron Axon Guidance Ephrin Receptor Signaling Pathway Regulation Of Axonogenesis Regulation Of Small GTPase Mediated Signal Transduction	Transcription By RNA Polymerase III Transcription Initiation At RNA Polymerase III Promoter RRNA Transcription TRNA Transcription 5S Class RRNA Transcription By RNA Polymerase III TRNA Transcription By RNA Polymerase III
Pathways		CDC42 GTPase cycle RAC1 GTPase cycle	RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter
Diseases		Duane retraction syndrome	None
GWAS		Post bronchodilator FEV1 ( 26634245 )	Asthma ( 31959851 ) Lymphocyte percentage of white cells ( 32888494 ) Mean reticulocyte volume ( 32888494 ) Mean spheric corpuscular volume ( 32888494 ) Neutrophil count ( 32888494 ) Neutrophil percentage of white cells ( 32888494 ) Red blood cell count ( 32888494 )
Interacting Genes		16 interacting genes: ACVR1 ADORA2A ANKK1 BMPR1B CDK5 CDK5R1 ERBB2 GTF3C1 HEMK1 HTR6 MAPK1 MAPK8IP2 NCK2 RAC1 RPS3A TGFBR1	25 interacting genes: AGTRAP AKTIP ASCC2 CHN1 CMTM5 CPE CSNK1E DEDD EZH2 FGFR3 GTF3C4 HGH1 IGFBP3 KLF6 MAGEA4 MAPK10 PRPF38A RBM23 SNU13 SUMO2 SUPT5H TBC1D17 UBC UBE3A WEE2-AS1
Entrez ID		1123	2975
HPRD ID		00319	07540
Ensembl ID		ENSG00000128656	ENSG00000077235
Uniprot IDs		P15882	Q12789
PDB IDs		2OSA 3CXL	8CLI 8CLJ 8CLK 8CLL
GO Terms Enriched among Interactors		Protein Kinase Activity Transforming Growth Factor Beta Receptor Activity, Type I Enzyme-linked Receptor Protein Signaling Pathway Positive Regulation Of Cell Communication Kinase Activity Positive Regulation Of Signaling Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Cell Projection Organization Transmembrane Receptor Protein Serine/threonine Kinase Activity Positive Regulation Of Signal Transduction Schwann Cell Development Regulation Of Apoptotic Signaling Pathway Protein Serine/threonine Kinase Activity Neuron Projection Guidance Axon Guidance Positive Regulation Of Protein Targeting To Membrane Motor Neuron Axon Guidance Dendrite Protein Kinase 5 Complex Cerebral Cortex Cell Migration Positive Regulation Of Intracellular Signal Transduction Regulation Of Cell Communication Regulation Of Signaling Regulation Of Protein Targeting To Membrane Positive Regulation Of Apoptotic Process Cell Migration Response To Growth Factor Positive Regulation Of Programmed Cell Death Positive Regulation Of Establishment Of Protein Localization Chemical Synaptic Transmission Plasma Membrane Bounded Cell Projection Organization ErbB-3 Class Receptor Binding Telencephalon Cell Migration Growth Factor Binding Regulation Of Signal Transduction Positive Regulation Of Apoptotic Signaling Pathway Forebrain Cell Migration Trans-synaptic Signaling SMAD Binding Synaptic Signaling Dendrite Morphogenesis Neuronal Cell Body Neuron Differentiation Regulation Of Protein Modification Process Positive Regulation Of Supramolecular Fiber Organization Activin Receptor Complex Activin Receptor Activity, Type I Anatomical Structure Morphogenesis Cell Surface Receptor Signaling Pathway	Regulation Of Circadian Rhythm