MYPN

Name	myopalladin
Structure	No pdb structure
Interactors	8 interactors: ACTN2 ACTN3 ANKRD1 ANKRD23 NEB NEBL PDLIM3 TTN
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Sarcomere Z Disc Axon I Band
	Molecular Function	Actin Binding Protein Binding Cytoskeletal Protein Binding SH3 Domain Binding Muscle Alpha-actinin Binding Cell-cell Adhesion Mediator Activity
	Biological Process	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Axon Guidance Sarcomere Organization Dendrite Self-avoidance
GWAS	Appendicular lean mass ( 33097823 ) Atrial fibrillation ( 30061737 ) Chronic kidney disease ( 31152163 ) Coffee consumption ( 31046077 ) Creatine kinase levels ( 29403010 ) Creatinine levels ( 29403010 ) Estimated glomerular filtration rate ( 30604766 31451708 31152163 31015462 ) Estimated glomerular filtration rate in non-diabetics ( 31451708 ) FEV1 ( 30804560 ) Glomerular filtration rate ( 29403010 ) Height ( 25282103 ) Hip circumference adjusted for BMI ( 34021172 ) Lung function (FVC) ( 30804560 28166213 ) Optic nerve measurement (disc area) ( 20395239 ) Peak expiratory flow ( 30804560 ) Psoriasis ( 25854761 )
Entrez ID	84665
HPRD ID	10536
Ensembl ID	ENSG00000138347
Uniprot IDs	A0A087WX60 Q86TC9
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Structural Constituent Of Muscle Z Disc I Band Actin Cytoskeleton Actin Filament Binding Cytoskeletal Protein Binding Titin Binding Response To Muscle Stretch Actin Cytoskeleton Organization Actin Binding Actin Filament-based Process Cardiac Muscle Thin Filament Assembly Sarcomere Organization Myofibril Sarcomere Actin Filament Organization Muscle Cell Development Actomyosin Structure Organization Muscle Alpha-actinin Binding Pseudopodium Cytoskeleton Organization Supramolecular Fiber Organization Focal Adhesion Assembly Response To Mechanical Stimulus Cell-substrate Junction Assembly Cardiac Muscle Cell Development Cell-substrate Junction Organization Cardiac Cell Development Cortical Actin Cytoskeleton Cardiac Muscle Tissue Morphogenesis Regulation Of Actin Cytoskeleton Organization Actin Filament Uncapping Positive Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate Striated Muscle Cell Development Muscle Tissue Morphogenesis Regulation Of Actin Filament-based Process Actin Filament Stress Fiber Titin Z Domain Binding Cytoplasm Regulation Of The Force Of Skeletal Muscle Contraction Positive Regulation Of Fast-twitch Skeletal Muscle Fiber Contraction Titin-telethonin Complex Structural Molecule Activity Conferring Elasticity Sarcomerogenesis Extracellular Exosome Phospholipase C-activating Angiotensin-activated Signaling Pathway Positive Regulation Of Bone Mineralization Involved In Bone Maturation Skeletal Muscle Myosin Thick Filament Assembly Regulation Of Cytoskeleton Organization