PLEKHG4

Name	pleckstrin homology and RhoGEF domain containing G4
Structure	No pdb structure
Novel Interactors	1 novel interactors: PLA2G15
Interactors	65 interactors: A1CF ARHGEF5 ARMC7 BEX2 CCDC120 CCDC187 CDC42 CDKN2C CHIC2 COIL DCUN1D5 DPPA3 DTX2 DUSP13B FAM161A FGD2 GATA3 GCM2 GSTZ1 HCK HOXB9 HOXC8 KRT3 KRT75 MALSU1 MATR3 MDFI METAP1 MSRB3 MTA1 MYEF2 MYOZ1 NATD1 OTX1 PFKFB1 PKP2 PRPF18 PRPF31 PSMB1 RHOA RIN1 SAXO1 SAXO4 SETD5 SH2D4A SHISA6 SIX1 SMCP SMG9 TBC1D22B TBX18 TEKT3 TENT5D TFAP2D TFG TRIM55 TRIM63 TSSK3 TTC23 USP2 VPS37C ZCCHC14 ZNF148 ZNF319 ZNF648
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Extrinsic Component Of Membrane
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Axon Guidance Regulation Of Small GTPase Mediated Signal Transduction
Pathways	RHOA GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle
GWAS	A body shape index ( 34021172 ) Heel bone mineral density ( 28869591 ) High density lipoprotein cholesterol levels ( 33339817 ) Refractive error ( 32231278 ) Waist circumference adjusted for body mass index ( 34021172 )
Entrez ID	25894
HPRD ID	10890
Ensembl ID	ENSG00000196155
Uniprot IDs	A0A024R6X4 Q58EX7
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Protein Binding Regulation Of Podosome Assembly Positive Regulation Of Ureteric Bud Formation