CASP3 and TRAF3 |
caspase 3, apoptosis-related cysteine peptidase |
TNF receptor-associated factor 3 |
- SMAC binds to IAPs
- SMAC-mediated dissociation of IAP:caspase complexes
- SMAC-mediated apoptotic response
- Cytochrome c-mediated apoptotic response
- Caspase-mediated cleavage of cytoskeletal proteins
- Degradation of the extracellular matrix
- Role of DCC in regulating apoptosis
- Activation of caspases through apoptosome-mediated cleavage
- Activation of DNA fragmentation factor
- Apoptotic factor-mediated response
- Programmed Cell Death
- Intrinsic Pathway for Apoptosis
- Signalling by NGF
- Apoptotic cleavage of cellular proteins
- Cell death signalling via NRAGE, NRIF and NADE
- Apoptotic execution phase
- p75 NTR receptor-mediated signalling
- Stimulation of the cell death response by PAK-2p34
- Apoptotic cleavage of cell adhesion proteins
- Signaling by Hippo
- Apoptosis induced DNA fragmentation
- Extrinsic Pathway
- NADE modulates death signalling
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- Activated TLR4 signalling
- RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
- TRAF3-dependent IRF activation pathway
- Toll-Like Receptors Cascades
- Negative regulators of RIG-I/MDA5 signaling
- TRIF-mediated TLR3/TLR4 signaling
- Toll Like Receptor 4 (TLR4) Cascade
- Toll Like Receptor 3 (TLR3) Cascade
- MyD88-independent cascade
- Innate Immune System
- Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
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- Minocycline
- 5-[4-(1-Carboxymethyl-2-Oxo-Propylcarbamoyl)-Benzylsulfamoyl]-2-Hydroxy-Benzoic Acid
- 2-HYDROXY-5-(2-MERCAPTO-ETHYLSULFAMOYL)-BENZOIC ACID
- methyl (3S)-3-[(tert-butoxycarbonyl)amino]-4-oxopentanoate
- 1-METHYL-5-(2-PHENOXYMETHYL-PYRROLIDINE-1-SULFONYL)-1H-INDOLE-2,3-DIONE
- [N-(3-DIBENZYLCARBAMOYL-OXIRANECARBONYL)-HYDRAZINO]-ACETIC ACID
- 4-[5-(2-CARBOXY-1-FORMYL-ETHYLCARBAMOYL)-PYRIDIN-3-YL]-BENZOIC ACID
- (1S)-2-oxo-1-phenyl-2-[(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-5-yl)amino]ethyl acetate
- (1S)-1-(3-chlorophenyl)-2-oxo-2-[(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-5-yl)amino]ethyl acetate
- N-[3-(2-fluoroethoxy)phenyl]-N\'-(1,3,4-trioxo-1,2,3,4-tetrahydroisoquinolin-6-yl)butanediamide
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CASP8 and MAP4K4 |
caspase 8, apoptosis-related cysteine peptidase |
mitogen-activated protein kinase kinase kinase kinase 4 |
- TRAIL signaling
- Death Receptor Signalling
- Caspase-8 activation by cleavage
- FasL/ CD95L signaling
- Activation, myristolyation of BID and translocation to mitochondria
- Caspase-mediated cleavage of cytoskeletal proteins
- Activated TLR4 signalling
- NOD1/2 Signaling Pathway
- Programmed Cell Death
- TRIF-mediated programmed cell death
- Innate Immune System
- Intrinsic Pathway for Apoptosis
- Regulation by c-FLIP
- Apoptotic cleavage of cellular proteins
- Dimerization of procaspase-8
- TRIF-mediated TLR3/TLR4 signaling
- Apoptotic execution phase
- MyD88-independent cascade
- RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
- Toll-Like Receptors Cascades
- Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
- Toll Like Receptor 4 (TLR4) Cascade
- Toll Like Receptor 3 (TLR3) Cascade
- NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
- Extrinsic Pathway
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- Oxidative Stress Induced Senescence
- Cellular Senescence
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RUNX2 and HDAC4 |
runt-related transcription factor 2 |
histone deacetylase 4 |
- Generic Transcription Pathway
- YAP1- and WWTR1 (TAZ)-stimulated gene expression
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- Signaling by NOTCH1 HD Domain Mutants in Cancer
- Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer
- Signaling by NOTCH
- Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant
- NOTCH1 Intracellular Domain Regulates Transcription
- Signaling by NOTCH1
- Signaling by NOTCH1 PEST Domain Mutants in Cancer
- Signaling by NOTCH1 in Cancer
- Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
- Constitutive Signaling by NOTCH1 PEST Domain Mutants
- FBXW7 Mutants and NOTCH1 in Cancer
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RUNX1T1 and TCF4 |
runt-related transcription factor 1; translocated to, 1 (cyclin D-related) |
transcription factor 4 |
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- CDO in myogenesis
- Myogenesis
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RUNX3 and HDAC4 |
runt-related transcription factor 3 |
histone deacetylase 4 |
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- Signaling by NOTCH1 HD Domain Mutants in Cancer
- Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer
- Signaling by NOTCH
- Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant
- NOTCH1 Intracellular Domain Regulates Transcription
- Signaling by NOTCH1
- Signaling by NOTCH1 PEST Domain Mutants in Cancer
- Signaling by NOTCH1 in Cancer
- Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
- Constitutive Signaling by NOTCH1 PEST Domain Mutants
- FBXW7 Mutants and NOTCH1 in Cancer
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SERPINH1 and FEZ1 |
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
fasciculation and elongation protein zeta 1 (zygin I) |
- Collagen formation
- Collagen biosynthesis and modifying enzymes
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SERPINH1 and BAG6 |
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
BCL2-associated athanogene 6 |
- Collagen formation
- Collagen biosynthesis and modifying enzymes
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CCNC and CTD |
cyclin C |
Coats disease |
- Loss of Function of TGFBR2 in Cancer
- PPARA activates gene expression
- Signaling by NOTCH1 HD Domain Mutants in Cancer
- Metabolism of lipids and lipoproteins
- Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer
- SMAD2/3 MH2 Domain Mutants in Cancer
- TGFBR1 LBD Mutants in Cancer
- SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
- Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
- Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant
- Generic Transcription Pathway
- Signaling by NOTCH1
- Transcriptional regulation of white adipocyte differentiation
- Signaling by NOTCH1 in Cancer
- Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
- FBXW7 Mutants and NOTCH1 in Cancer
- TGFBR2 MSI Frameshift Mutants in Cancer
- Fatty acid, triacylglycerol, and ketone body metabolism
- SMAD2/3 Phosphorylation Motif Mutants in Cancer
- Loss of Function of SMAD2/3 in Cancer
- Signaling by NOTCH
- TGFBR2 Kinase Domain Mutants in Cancer
- Loss of Function of SMAD4 in Cancer
- TGFBR1 KD Mutants in Cancer
- Loss of Function of TGFBR1 in Cancer
- NOTCH1 Intracellular Domain Regulates Transcription
- Signaling by TGF-beta Receptor Complex in Cancer
- Signaling by TGF-beta Receptor Complex
- Signaling by NOTCH1 PEST Domain Mutants in Cancer
- Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
- Constitutive Signaling by NOTCH1 PEST Domain Mutants
- SMAD4 MH2 Domain Mutants in Cancer
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CCNH and CTD |
cyclin H |
Coats disease |
- RNA Polymerase II Promoter Escape
- Formation of HIV-1 elongation complex containing HIV-1 Tat
- RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
- RNA Polymerase I Chain Elongation
- RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
- Tat-mediated elongation of the HIV-1 transcript
- Cyclin E associated events during G1/S transition
- Formation of transcription-coupled NER (TC-NER) repair complex
- Dual incision reaction in TC-NER
- NoRC negatively regulates rRNA expression
- G1/S Transition
- Mitotic G1-G1/S phases
- S Phase
- Late Phase of HIV Life Cycle
- Formation of RNA Pol II elongation complex
- Global Genomic NER (GG-NER)
- RNA Polymerase II Transcription Initiation And Promoter Clearance
- Cyclin A:Cdk2-associated events at S phase entry
- Mitotic G2-G2/M phases
- Transcription of the HIV genome
- Nucleotide Excision Repair
- RNA Polymerase II Transcription
- RNA Polymerase I Transcription Initiation
- HIV Infection
- RNA Polymerase I Promoter Clearance
- Formation of the Early Elongation Complex
- G2/M Transition
- RNA Pol II CTD phosphorylation and interaction with CE
- RNA Polymerase II Pre-transcription Events
- HIV Transcription Initiation
- HIV Life Cycle
- RNA Pol II CTD phosphorylation and interaction with CE
- Cyclin A/B1 associated events during G2/M transition
- RNA Polymerase II HIV Promoter Escape
- HIV Transcription Elongation
- Dual incision reaction in GG-NER
- RNA Polymerase I Transcription
- mRNA Capping
- RNA Polymerase I Promoter Escape
- RNA Polymerase I Transcription Termination
- G1 Phase
- Epigenetic regulation of gene expression
- Negative epigenetic regulation of rRNA expression
- Cell Cycle, Mitotic
- Cyclin D associated events in G1
- Transcription-coupled NER (TC-NER)
- Formation of HIV elongation complex in the absence of HIV Tat
- Formation of the HIV-1 Early Elongation Complex
- Formation of incision complex in GG-NER
- RNA Polymerase II Transcription Initiation
- RNA Polymerase II Transcription Elongation
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CCNT1 and CTD |
cyclin T1 |
Coats disease |
- Loss of Function of TGFBR2 in Cancer
- Formation of HIV-1 elongation complex containing HIV-1 Tat
- RNA Polymerase II Transcription
- HIV Infection
- SMAD2/3 MH2 Domain Mutants in Cancer
- Tat-mediated elongation of the HIV-1 transcript
- Tat-mediated HIV elongation arrest and recovery
- TGFBR1 LBD Mutants in Cancer
- RNA Polymerase II Pre-transcription Events
- SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
- Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
- HIV elongation arrest and recovery
- HIV Life Cycle
- Generic Transcription Pathway
- HIV Transcription Elongation
- TGFBR2 MSI Frameshift Mutants in Cancer
- SMAD2/3 Phosphorylation Motif Mutants in Cancer
- Loss of Function of SMAD2/3 in Cancer
- TGFBR2 Kinase Domain Mutants in Cancer
- Host Interactions of HIV factors
- Loss of Function of SMAD4 in Cancer
- Interactions of Tat with host cellular proteins
- TGFBR1 KD Mutants in Cancer
- Pausing and recovery of Tat-mediated HIV elongation
- Loss of Function of TGFBR1 in Cancer
- Late Phase of HIV Life Cycle
- Formation of RNA Pol II elongation complex
- Signaling by TGF-beta Receptor Complex
- Signaling by TGF-beta Receptor Complex in Cancer
- Pausing and recovery of HIV elongation
- Formation of HIV elongation complex in the absence of HIV Tat
- Transcription of the HIV genome
- SMAD4 MH2 Domain Mutants in Cancer
- RNA Polymerase II Transcription Elongation
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CD4 and CXCL12 |
CD4 molecule |
chemokine (C-X-C motif) ligand 12 |
- Vpu mediated degradation of CD4
- Downstream TCR signaling
- Generation of second messenger molecules
- Translocation of ZAP-70 to Immunological synapse
- Costimulation by the CD28 family
- Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
- HIV Infection
- Host Interactions of HIV factors
- The role of Nef in HIV-1 replication and disease pathogenesis
- Early Phase of HIV Life Cycle
- HIV Life Cycle
- TCR signaling
- Alpha-defensins
- PD-1 signaling
- Defensins
- Phosphorylation of CD3 and TCR zeta chains
- Nef Mediated CD4 Down-regulation
- Binding and entry of HIV virion
- Innate Immune System
- Adaptive Immune System
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- Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
- Signaling by GPCR
- Class A/1 (Rhodopsin-like receptors)
- Signaling by ERBB4
- GPCR ligand binding
- Metabolic disorders of biological oxidation enzymes
- GPCR downstream signaling
- Nuclear signaling by ERBB4
- Peptide ligand-binding receptors
- Chemokine receptors bind chemokines
- G alpha (i) signalling events
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CD27 and TRAF3 |
CD27 molecule |
TNF receptor-associated factor 3 |
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- Activated TLR4 signalling
- RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
- TRAF3-dependent IRF activation pathway
- Toll-Like Receptors Cascades
- Negative regulators of RIG-I/MDA5 signaling
- TRIF-mediated TLR3/TLR4 signaling
- Toll Like Receptor 4 (TLR4) Cascade
- Toll Like Receptor 3 (TLR3) Cascade
- MyD88-independent cascade
- Innate Immune System
- Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
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TNFRSF8 and TRAF3 |
tumor necrosis factor receptor superfamily, member 8 |
TNF receptor-associated factor 3 |
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- Activated TLR4 signalling
- RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
- TRAF3-dependent IRF activation pathway
- Toll-Like Receptors Cascades
- Negative regulators of RIG-I/MDA5 signaling
- TRIF-mediated TLR3/TLR4 signaling
- Toll Like Receptor 4 (TLR4) Cascade
- Toll Like Receptor 3 (TLR3) Cascade
- MyD88-independent cascade
- Innate Immune System
- Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
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SIGLEC6 and TCF4 |
sialic acid binding Ig-like lectin 6 |
transcription factor 4 |
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- CDO in myogenesis
- Myogenesis
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CD40 and TRAF3 |
CD40 molecule, TNF receptor superfamily member 5 |
TNF receptor-associated factor 3 |
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- Activated TLR4 signalling
- RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
- TRAF3-dependent IRF activation pathway
- Toll-Like Receptors Cascades
- Negative regulators of RIG-I/MDA5 signaling
- TRIF-mediated TLR3/TLR4 signaling
- Toll Like Receptor 4 (TLR4) Cascade
- Toll Like Receptor 3 (TLR3) Cascade
- MyD88-independent cascade
- Innate Immune System
- Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
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CD74 and HLA-DQA1 |
CD74 molecule, major histocompatibility complex, class II invariant chain |
major histocompatibility complex, class II, DQ alpha 1 |
- MHC class II antigen presentation
- Adaptive Immune System
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- Generation of second messenger molecules
- Downstream TCR signaling
- Costimulation by the CD28 family
- Translocation of ZAP-70 to Immunological synapse
- Interferon Signaling
- Cytokine Signaling in Immune system
- Interferon gamma signaling
- TCR signaling
- MHC class II antigen presentation
- PD-1 signaling
- Phosphorylation of CD3 and TCR zeta chains
- Adaptive Immune System
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CDK1 and KIF26B |
cyclin-dependent kinase 1 |
kinesin family member 26B |
- Phosphorylation of the APC/C
- Signaling by FGFR in disease
- Phosphorylation of Emi1
- Signaling by EGFRvIII in Cancer
- Toll Like Receptor TLR1:TLR2 Cascade
- Toll Like Receptor 5 (TLR5) Cascade
- Gastrin-CREB signalling pathway via PKC and MAPK
- MyD88 dependent cascade initiated on endosome
- SOS-mediated signalling
- Mitotic G1-G1/S phases
- SHC-mediated signalling
- Recruitment of mitotic centrosome proteins and complexes
- TRIF-mediated TLR3/TLR4 signaling
- ERK1 activation
- Nuclear Pore Complex (NPC) Disassembly
- APC/C:Cdc20 mediated degradation of mitotic proteins
- Regulation of APC/C activators between G1/S and early anaphase
- ERK1 activation
- APC/C:Cdc20 mediated degradation of Cyclin B
- Signaling by VEGF
- Resolution of Sister Chromatid Cohesion
- Downstream signal transduction
- Signalling to RAS
- Toll Like Receptor 3 (TLR3) Cascade
- Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins
- APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint
- Interleukin-2 signaling
- Mitotic G2-G2/M phases
- Frs2-mediated activation
- MASTL Facilitates Mitotic Progression
- Axon guidance
- IRS-mediated signalling
- G2/M Transition
- VEGFA-VEGFR2 Pathway
- Activated TLR4 signalling
- VEGFR2 mediated cell proliferation
- GRB2 events in ERBB2 signaling
- Cyclin A/B1 associated events during G2/M transition
- Loss of Nlp from mitotic centrosomes
- MyD88:Mal cascade initiated on plasma membrane
- TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
- NCAM signaling for neurite out-growth
- RAF/MAP kinase cascade
- Signalling to p38 via RIT and RIN
- Innate Immune System
- Condensation of Prometaphase Chromosomes
- Signaling by Insulin receptor
- E2F mediated regulation of DNA replication
- Insulin receptor signalling cascade
- Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes
- G0 and Early G1
- Signaling by Ligand-Responsive EGFR Variants in Cancer
- IRS-related events
- SHC-related events
- Signaling by FGFR
- ARMS-mediated activation
- Toll-Like Receptors Cascades
- Toll Like Receptor 10 (TLR10) Cascade
- Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
- E2F-enabled inhibition of pre-replication complex formation
- Regulation of mitotic cell cycle
- Cell Cycle Checkpoints
- Signaling by GPCR
- G2/M Checkpoints
- Mitotic Prophase
- Golgi Cisternae Pericentriolar Stack Reorganization
- FCERI mediated MAPK activation
- Regulation of PLK1 Activity at G2/M Transition
- SHC1 events in ERBB2 signaling
- Signaling by SCF-KIT
- DAP12 signaling
- G1/S Transition
- G1/S-Specific Transcription
- Toll Like Receptor 9 (TLR9) Cascade
- G2/M DNA replication checkpoint
- Signaling by PDGF
- DAP12 interactions
- SHC-related events triggered by IGF1R
- GRB2 events in EGFR signaling
- Signaling by ERBB4
- APC/C-mediated degradation of cell cycle proteins
- Toll Like Receptor 2 (TLR2) Cascade
- Signaling by ERBB2
- Signaling by EGFR
- Signaling by Interleukins
- SHC1 events in ERBB4 signaling
- Toll Like Receptor 4 (TLR4) Cascade
- Fc epsilon receptor (FCERI) signaling
- Signaling by EGFR in Cancer
- Condensation of Prophase Chromosomes
- Signaling by Leptin
- Signalling to ERKs
- Mitotic Prometaphase
- Prolonged ERK activation events
- Organelle biogenesis and maintenance
- ERK activation
- Toll Like Receptor 7/8 (TLR7/8) Cascade
- Activation of NIMA Kinases NEK9, NEK6, NEK7
- Nuclear Envelope Breakdown
- IGF1R signaling cascade
- Recruitment of NuMA to mitotic centrosomes
- Cyclin B2 mediated events
- Toll Like Receptor TLR6:TLR2 Cascade
- M Phase
- IRS-related events triggered by IGF1R
- MyD88 cascade initiated on plasma membrane
- ERK activation
- Downstream signaling of activated FGFR
- Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
- Signalling by NGF
- SOS-mediated signalling
- G2/M DNA damage checkpoint
- MAP kinase activation in TLR cascade
- SHC-mediated signalling
- Depolymerisation of the Nuclear Lamina
- Assembly of the primary cilium
- Cytokine Signaling in Immune system
- NGF signalling via TRKA from the plasma membrane
- Signaling by Overexpressed Wild-Type EGFR in Cancer
- MyD88-independent cascade
- Anchoring of the basal body to the plasma membrane
- Cell Cycle, Mitotic
- SHC1 events in EGFR signaling
- Loss of proteins required for interphase microtubule organization from the centrosome
- FRS2-mediated cascade
- IRS-mediated signalling
- Centrosome maturation
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- Indirubin-3\'-Monoxime
- Olomoucine
- Hymenialdisine
- SU9516
- Flavopiridol
- Alsterpaullone
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CDK1 and IL3RA |
cyclin-dependent kinase 1 |
interleukin 3 receptor, alpha (low affinity) |
- Phosphorylation of the APC/C
- Signaling by FGFR in disease
- Phosphorylation of Emi1
- Signaling by EGFRvIII in Cancer
- Toll Like Receptor TLR1:TLR2 Cascade
- Toll Like Receptor 5 (TLR5) Cascade
- Gastrin-CREB signalling pathway via PKC and MAPK
- MyD88 dependent cascade initiated on endosome
- SOS-mediated signalling
- Mitotic G1-G1/S phases
- SHC-mediated signalling
- Recruitment of mitotic centrosome proteins and complexes
- TRIF-mediated TLR3/TLR4 signaling
- ERK1 activation
- Nuclear Pore Complex (NPC) Disassembly
- APC/C:Cdc20 mediated degradation of mitotic proteins
- Regulation of APC/C activators between G1/S and early anaphase
- ERK1 activation
- APC/C:Cdc20 mediated degradation of Cyclin B
- Signaling by VEGF
- Resolution of Sister Chromatid Cohesion
- Downstream signal transduction
- Signalling to RAS
- Toll Like Receptor 3 (TLR3) Cascade
- Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins
- APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint
- Interleukin-2 signaling
- Mitotic G2-G2/M phases
- Frs2-mediated activation
- MASTL Facilitates Mitotic Progression
- Axon guidance
- IRS-mediated signalling
- G2/M Transition
- VEGFA-VEGFR2 Pathway
- Activated TLR4 signalling
- VEGFR2 mediated cell proliferation
- GRB2 events in ERBB2 signaling
- Cyclin A/B1 associated events during G2/M transition
- Loss of Nlp from mitotic centrosomes
- MyD88:Mal cascade initiated on plasma membrane
- TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
- NCAM signaling for neurite out-growth
- RAF/MAP kinase cascade
- Signalling to p38 via RIT and RIN
- Innate Immune System
- Condensation of Prometaphase Chromosomes
- Signaling by Insulin receptor
- E2F mediated regulation of DNA replication
- Insulin receptor signalling cascade
- Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes
- G0 and Early G1
- Signaling by Ligand-Responsive EGFR Variants in Cancer
- IRS-related events
- SHC-related events
- Signaling by FGFR
- ARMS-mediated activation
- Toll-Like Receptors Cascades
- Toll Like Receptor 10 (TLR10) Cascade
- Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
- E2F-enabled inhibition of pre-replication complex formation
- Regulation of mitotic cell cycle
- Cell Cycle Checkpoints
- Signaling by GPCR
- G2/M Checkpoints
- Mitotic Prophase
- Golgi Cisternae Pericentriolar Stack Reorganization
- FCERI mediated MAPK activation
- Regulation of PLK1 Activity at G2/M Transition
- SHC1 events in ERBB2 signaling
- Signaling by SCF-KIT
- DAP12 signaling
- G1/S Transition
- G1/S-Specific Transcription
- Toll Like Receptor 9 (TLR9) Cascade
- G2/M DNA replication checkpoint
- Signaling by PDGF
- DAP12 interactions
- SHC-related events triggered by IGF1R
- GRB2 events in EGFR signaling
- Signaling by ERBB4
- APC/C-mediated degradation of cell cycle proteins
- Toll Like Receptor 2 (TLR2) Cascade
- Signaling by ERBB2
- Signaling by EGFR
- Signaling by Interleukins
- SHC1 events in ERBB4 signaling
- Toll Like Receptor 4 (TLR4) Cascade
- Fc epsilon receptor (FCERI) signaling
- Signaling by EGFR in Cancer
- Condensation of Prophase Chromosomes
- Signaling by Leptin
- Signalling to ERKs
- Mitotic Prometaphase
- Prolonged ERK activation events
- Organelle biogenesis and maintenance
- ERK activation
- Toll Like Receptor 7/8 (TLR7/8) Cascade
- Activation of NIMA Kinases NEK9, NEK6, NEK7
- Nuclear Envelope Breakdown
- IGF1R signaling cascade
- Recruitment of NuMA to mitotic centrosomes
- Cyclin B2 mediated events
- Toll Like Receptor TLR6:TLR2 Cascade
- M Phase
- IRS-related events triggered by IGF1R
- MyD88 cascade initiated on plasma membrane
- ERK activation
- Downstream signaling of activated FGFR
- Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
- Signalling by NGF
- SOS-mediated signalling
- G2/M DNA damage checkpoint
- MAP kinase activation in TLR cascade
- SHC-mediated signalling
- Depolymerisation of the Nuclear Lamina
- Assembly of the primary cilium
- Cytokine Signaling in Immune system
- NGF signalling via TRKA from the plasma membrane
- Signaling by Overexpressed Wild-Type EGFR in Cancer
- MyD88-independent cascade
- Anchoring of the basal body to the plasma membrane
- Cell Cycle, Mitotic
- SHC1 events in EGFR signaling
- Loss of proteins required for interphase microtubule organization from the centrosome
- FRS2-mediated cascade
- IRS-mediated signalling
- Centrosome maturation
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- Signaling by GPCR
- G-protein beta:gamma signalling
- Cytokine Signaling in Immune system
- GPCR downstream signaling
- Signaling by Interleukins
- Interleukin receptor SHC signaling
- G beta:gamma signalling through PI3Kgamma
- Interleukin receptor SHC signaling
- GPVI-mediated activation cascade
- Interleukin-2 signaling
- Platelet activation, signaling and aggregation
- Interleukin-3, 5 and GM-CSF signaling
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- Indirubin-3\'-Monoxime
- Olomoucine
- Hymenialdisine
- SU9516
- Flavopiridol
- Alsterpaullone
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CDC5L and DISC1 |
cell division cycle 5-like |
disrupted in schizophrenia 1 |
- Processing of Capped Intron-Containing Pre-mRNA
- mRNA Splicing
- mRNA Splicing - Major Pathway
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CDC5L and SYNE1 |
cell division cycle 5-like |
spectrin repeat containing, nuclear envelope 1 |
- Processing of Capped Intron-Containing Pre-mRNA
- mRNA Splicing
- mRNA Splicing - Major Pathway
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