CCNT1 and CTD

Number of citations of the paper that reports this interaction (PMID 18566585)
76

Data Source:
BioGRID (enzymatic study, enzymatic study, enzymatic study)

		CCNT1	CTD
Gene Name		cyclin T1	Coats disease
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Positive Transcription Elongation Factor Complex B
	Molecular Function	DNA Binding Chromatin Binding Protein Binding SnRNA Binding Protein Kinase Binding Transcription Regulatory Region DNA Binding
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Protein Phosphorylation Cell Cycle Transforming Growth Factor Beta Receptor Signaling Pathway Gene Expression Viral Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Viral Transcription Cell Division
Pathways		Loss of Function of TGFBR2 in Cancer Formation of HIV-1 elongation complex containing HIV-1 Tat RNA Polymerase II Transcription HIV Infection SMAD2/3 MH2 Domain Mutants in Cancer Tat-mediated elongation of the HIV-1 transcript Tat-mediated HIV elongation arrest and recovery TGFBR1 LBD Mutants in Cancer RNA Polymerase II Pre-transcription Events SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer HIV elongation arrest and recovery HIV Life Cycle Generic Transcription Pathway HIV Transcription Elongation TGFBR2 MSI Frameshift Mutants in Cancer SMAD2/3 Phosphorylation Motif Mutants in Cancer Loss of Function of SMAD2/3 in Cancer TGFBR2 Kinase Domain Mutants in Cancer Host Interactions of HIV factors Loss of Function of SMAD4 in Cancer Interactions of Tat with host cellular proteins TGFBR1 KD Mutants in Cancer Pausing and recovery of Tat-mediated HIV elongation Loss of Function of TGFBR1 in Cancer Late Phase of HIV Life Cycle Formation of RNA Pol II elongation complex Signaling by TGF-beta Receptor Complex Signaling by TGF-beta Receptor Complex in Cancer Pausing and recovery of HIV elongation Formation of HIV elongation complex in the absence of HIV Tat Transcription of the HIV genome SMAD4 MH2 Domain Mutants in Cancer RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS			Schizophrenia ( 23212062)
Protein-Protein Interactions		26 interactors: AFF4 AHR BRD4 CDK9 CTD ESR1 GRIPAP1 GRN GTF2F1 HEXIM1 HEXIM2 HIC2 HTATSF1 HTN1 KAT2B MBP MDFIC MYC NCOA2 NUFIP1 PML POLR2A PURA RN7SK SKP2 SUPT5H	13 interactors: CCNC CCNH CCNT1 CDK7 CDK8 CDK9 CPSF1 GTF2H1 MNAT1 POLR2A TBP TTK WAC
Entrez ID		904	1283
HPRD ID		03938
Ensembl ID		ENSG00000129315
Uniprot IDs		A8K4M5 A9XU13 O60563
PDB IDs		2PK2 3BLH 3BLQ 3BLR 3LQ5 3MI9 3MIA 3MY1 3TN8 3TNH 3TNI 4BCF 4BCG 4BCH 4BCI 4BCJ 4EC8 4EC9 4IMY
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Macromolecule Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Positive Regulation Of Viral Transcription Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Viral Process Cellular Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Viral Transcription Regulation Of Viral Process Positive Regulation Of Viral Process Positive Regulation Of Cellular Biosynthetic Process Nitrogen Compound Metabolic Process Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process DNA-templated Transcription, Initiation Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of DNA-templated Transcription, Elongation Negative Regulation Of Cell Cycle Transcription Elongation From RNA Polymerase II Promoter Chromatin Remodeling DNA-templated Transcription, Elongation Regulation Of Metabolic Process Regulation Of Cell Cycle Positive Regulation Of DNA-templated Transcription, Elongation Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity 7-methylguanosine MRNA Capping Positive Regulation Of Metabolic Process	Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Transcription Elongation From RNA Polymerase II Promoter DNA-templated Transcription, Elongation Positive Regulation Of Viral Transcription Regulation Of Viral Transcription Positive Regulation Of Viral Process Transcription From RNA Polymerase II Promoter Regulation Of Viral Process DNA-templated Transcription, Termination Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter 7-methylguanosine MRNA Capping Transcription From RNA Polymerase I Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression 7-methylguanosine RNA Capping Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process RNA Biosynthetic Process Transcription-coupled Nucleotide-excision Repair Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Viral Process Regulation Of Cell Cycle Nucleotide-excision Repair, DNA Damage Removal Negative Regulation Of Gene Expression, Epigenetic RNA Metabolic Process Nucleotide-excision Repair Positive Regulation Of Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process MRNA Processing Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression, Epigenetic Protein Phosphorylation Cellular Nitrogen Compound Metabolic Process Regulation Of Cellular Protein Metabolic Process Cellular Response To DNA Damage Stimulus MRNA Metabolic Process Regulation Of Protein Metabolic Process Nitrogen Compound Metabolic Process RNA Processing
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Tagcloud (Difference) ?			ana anas antinuclear assayed awaited connective discordant discrimination dsdna elisa elisas erythematosus fana gives immunosorbent jo labor lupus mana mesacup personnel rnp sera ss ssdna subjective suitable trained uses
Tagcloud (Intersection) ?