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SLC23A2 and AGPAT2
Number of citations of the paper that reports this interaction (PMID
21988832
)
14
Data Source:
BioGRID
(two hybrid)
SLC23A2
AGPAT2
Gene Name
solute carrier family 23 (ascorbic acid transporter), member 2
1-acylglycerol-3-phosphate O-acyltransferase 2
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Plasma Membrane
Integral Component Of Plasma Membrane
Basal Plasma Membrane
Membrane
Integral Component Of Membrane
Basolateral Plasma Membrane
Apical Plasma Membrane
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Integral Component Of Membrane
Molecular Function
L-ascorbate:sodium Symporter Activity
Sodium-dependent Multivitamin Transmembrane Transporter Activity
Nucleobase Transmembrane Transporter Activity
L-ascorbic Acid Transporter Activity
Sodium-dependent L-ascorbate Transmembrane Transporter Activity
1-acylglycerol-3-phosphate O-acyltransferase Activity
Biological Process
Nucleobase-containing Compound Metabolic Process
Vitamin Metabolic Process
Water-soluble Vitamin Metabolic Process
Sodium Ion Transport
Response To Oxidative Stress
Nucleobase Transport
L-ascorbic Acid Transport
Molecular Hydrogen Transport
L-ascorbic Acid Metabolic Process
Vitamin Transmembrane Transport
Small Molecule Metabolic Process
Transepithelial L-ascorbic Acid Transport
Positive Regulation Of Cytokine Production
Positive Regulation Of Cytokine-mediated Signaling Pathway
Phospholipid Metabolic Process
Phosphatidic Acid Biosynthetic Process
Epidermis Development
CDP-diacylglycerol Biosynthetic Process
Triglyceride Biosynthetic Process
Cellular Lipid Metabolic Process
Small Molecule Metabolic Process
Glycerophospholipid Biosynthetic Process
Pathways
Metabolism of vitamins and cofactors
Defective CD320 causes methylmalonic aciduria
Defective GIF causes intrinsic factor deficiency
Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF
Defective HLCS causes multiple carboxylase deficiency
Defective MMAB causes methylmalonic aciduria type cblB
Defective BTD causes biotidinase deficiency
Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC
Defective MTR causes methylmalonic aciduria and homocystinuria type cblG
Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD
Vitamin C (ascorbate) metabolism
Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE
Defective MMAA causes methylmalonic aciduria type cblA
Defective CUBN causes hereditary megaloblastic anemia 1
Defective AMN causes hereditary megaloblastic anemia 1
Defective MUT causes methylmalonic aciduria mut type
Metabolism of water-soluble vitamins and cofactors
Defects in biotin (Btn) metabolism
Defective TCN2 causes hereditary megaloblastic anemia
Defects in cobalamin (B12) metabolism
Defects in vitamin and cofactor metabolism
Synthesis of PA
Fatty acid, triacylglycerol, and ketone body metabolism
Metabolism of lipids and lipoproteins
Phospholipid metabolism
Glycerophospholipid biosynthesis
Triglyceride Biosynthesis
Drugs
Diseases
GWAS
Protein-Protein Interactions
2 interactors:
AGPAT2
NEDD4
6 interactors:
ABCG8
ANKRD28
GMPS
PHF11
PHRF1
SLC23A2
Entrez ID
9962
10555
HPRD ID
04811
04373
Ensembl ID
ENSG00000089057
ENSG00000169692
Uniprot IDs
B4DJZ1
Q9UGH3
O15120
PDB IDs
Enriched GO Terms of Interacting Partners
?
Transmission Of Virus
Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage
Development Involved In Symbiotic Interaction
Progesterone Receptor Signaling Pathway
Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage
Glucocorticoid Receptor Signaling Pathway
Protein Targeting To Lysosome
CDP-diacylglycerol Biosynthetic Process
Negative Regulation Of Sodium Ion Transport
CDP-diacylglycerol Metabolic Process
Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
Protein Localization To Lysosome
Receptor Catabolic Process
Protein Targeting To Vacuole
Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Establishment Of Protein Localization To Vacuole
Phosphatidic Acid Biosynthetic Process
Phosphatidic Acid Metabolic Process
Regulation Of Potassium Ion Transmembrane Transporter Activity
Positive Regulation Of Cytokine-mediated Signaling Pathway
Positive Regulation Of Response To Cytokine Stimulus
Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
Protein K63-linked Ubiquitination
Positive Regulation Of Signal Transduction
Endocardial Cushion Development
Regulation Of Potassium Ion Transmembrane Transport
Protein Monoubiquitination
Receptor Internalization
Triglyceride Biosynthetic Process
Lysosomal Transport
Neuromuscular Junction Development
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Regulation Of DNA-templated Transcription In Response To Stress
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Cellular Response To UV
Regulation Of Potassium Ion Transport
Outflow Tract Morphogenesis
Tissue Development
Regulation Of Sodium Ion Transport
Positive Regulation Of Phosphatidylinositol 3-kinase Signaling
Regulation Of Dendrite Morphogenesis
Intracellular Steroid Hormone Receptor Signaling Pathway
Vacuolar Transport
Receptor Metabolic Process
Regulation Of Phosphatidylinositol 3-kinase Signaling
Regulation Of Synapse Organization
Regulation Of Synapse Structure Or Activity
Cellular Response To Light Stimulus
Triglyceride Metabolic Process
Negative Regulation Of Ion Transport
Negative Regulation Of Intestinal Phytosterol Absorption
Negative Regulation Of Intestinal Cholesterol Absorption
Transepithelial L-ascorbic Acid Transport
Molecular Hydrogen Transport
L-ascorbic Acid Transport
GMP Biosynthetic Process
Nucleobase Transport
Intestinal Cholesterol Absorption
GMP Metabolic Process
Regulation Of Intestinal Cholesterol Absorption
Negative Regulation Of Cholesterol Transport
Lipid Digestion
L-ascorbic Acid Metabolic Process
Transepithelial Transport
Purine Nucleobase Biosynthetic Process
Organic Anion Transport
Vitamin Transmembrane Transport
Response To Drug
Intestinal Absorption
Negative Regulation Of Lipid Transport
Nucleobase-containing Compound Metabolic Process
Cholesterol Efflux
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Anion Transport
Glutamine Metabolic Process
Regulation Of Cholesterol Transport
Small Molecule Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Purine Nucleobase Metabolic Process
Vitamin Transport
Excretion
Nitrogen Compound Metabolic Process
Carbohydrate Transmembrane Transport
Pigment Biosynthetic Process
Sterol Transport
Cholesterol Transport
Purine Ribonucleoside Monophosphate Biosynthetic Process
Cholesterol Homeostasis
Sterol Homeostasis
Carboxylic Acid Metabolic Process
Water-soluble Vitamin Metabolic Process
Tagcloud
?
abhd5
anomaly
atgl
cgi
ctgm
dgat1
diverge
enteropathy
gk
glycerol
gpd1
hsl
ichthyosis
inborn
jordan
lipe
lipodystrophy
loosing
lpin1
lpin2
majeed
nlsd
perilipin
pnpla2
pseudohypertriglyceridemia
rhabdomyolysis
steatosis
tgs
vacuolated
Tagcloud (Difference)
?
abhd5
anomaly
atgl
cgi
ctgm
dgat1
diverge
enteropathy
gk
glycerol
gpd1
hsl
ichthyosis
inborn
jordan
lipe
lipodystrophy
loosing
lpin1
lpin2
majeed
nlsd
perilipin
pnpla2
pseudohypertriglyceridemia
rhabdomyolysis
steatosis
tgs
vacuolated
Tagcloud (Intersection)
?