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SLC23A2
Gene Name
solute carrier family 23 (ascorbic acid transporter), member 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Plasma Membrane
Integral Component Of Plasma Membrane
Basal Plasma Membrane
Membrane
Integral Component Of Membrane
Basolateral Plasma Membrane
Apical Plasma Membrane
Molecular Function
L-ascorbate:sodium Symporter Activity
Sodium-dependent Multivitamin Transmembrane Transporter Activity
Nucleobase Transmembrane Transporter Activity
L-ascorbic Acid Transporter Activity
Sodium-dependent L-ascorbate Transmembrane Transporter Activity
Biological Process
Nucleobase-containing Compound Metabolic Process
Vitamin Metabolic Process
Water-soluble Vitamin Metabolic Process
Sodium Ion Transport
Response To Oxidative Stress
Nucleobase Transport
L-ascorbic Acid Transport
Molecular Hydrogen Transport
L-ascorbic Acid Metabolic Process
Vitamin Transmembrane Transport
Small Molecule Metabolic Process
Transepithelial L-ascorbic Acid Transport
Pathways
Metabolism of vitamins and cofactors
Defective CD320 causes methylmalonic aciduria
Defective GIF causes intrinsic factor deficiency
Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF
Defective HLCS causes multiple carboxylase deficiency
Defective MMAB causes methylmalonic aciduria type cblB
Defective BTD causes biotidinase deficiency
Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC
Defective MTR causes methylmalonic aciduria and homocystinuria type cblG
Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD
Vitamin C (ascorbate) metabolism
Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE
Defective MMAA causes methylmalonic aciduria type cblA
Defective CUBN causes hereditary megaloblastic anemia 1
Defective AMN causes hereditary megaloblastic anemia 1
Defective MUT causes methylmalonic aciduria mut type
Metabolism of water-soluble vitamins and cofactors
Defects in biotin (Btn) metabolism
Defective TCN2 causes hereditary megaloblastic anemia
Defects in cobalamin (B12) metabolism
Defects in vitamin and cofactor metabolism
Drugs
Diseases
GWAS
Protein-protein Interactions
2 interactors:
AGPAT2
NEDD4
Entrez ID
9962
HPRD ID
04811
Ensembl ID
ENSG00000089057
Uniprot IDs
B4DJZ1
Q9UGH3
PDB IDs
Enriched GO Terms of Interacting Partners
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Transmission Of Virus
Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage
Development Involved In Symbiotic Interaction
Progesterone Receptor Signaling Pathway
Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage
Glucocorticoid Receptor Signaling Pathway
Protein Targeting To Lysosome
CDP-diacylglycerol Biosynthetic Process
Negative Regulation Of Sodium Ion Transport
CDP-diacylglycerol Metabolic Process
Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
Protein Localization To Lysosome
Receptor Catabolic Process
Protein Targeting To Vacuole
Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Establishment Of Protein Localization To Vacuole
Phosphatidic Acid Biosynthetic Process
Phosphatidic Acid Metabolic Process
Regulation Of Potassium Ion Transmembrane Transporter Activity
Positive Regulation Of Cytokine-mediated Signaling Pathway
Positive Regulation Of Response To Cytokine Stimulus
Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
Protein K63-linked Ubiquitination
Positive Regulation Of Signal Transduction
Endocardial Cushion Development
Regulation Of Potassium Ion Transmembrane Transport
Protein Monoubiquitination
Receptor Internalization
Triglyceride Biosynthetic Process
Lysosomal Transport
Neuromuscular Junction Development
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Regulation Of DNA-templated Transcription In Response To Stress
Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Cellular Response To UV
Regulation Of Potassium Ion Transport
Outflow Tract Morphogenesis
Tissue Development
Regulation Of Sodium Ion Transport
Positive Regulation Of Phosphatidylinositol 3-kinase Signaling
Regulation Of Dendrite Morphogenesis
Intracellular Steroid Hormone Receptor Signaling Pathway
Vacuolar Transport
Receptor Metabolic Process
Regulation Of Phosphatidylinositol 3-kinase Signaling
Regulation Of Synapse Organization
Regulation Of Synapse Structure Or Activity
Cellular Response To Light Stimulus
Triglyceride Metabolic Process
Negative Regulation Of Ion Transport
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