SLC23A2

Gene Name		solute carrier family 23 (ascorbic acid transporter), member 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Basal Plasma Membrane Membrane Integral Component Of Membrane Basolateral Plasma Membrane Apical Plasma Membrane
	Molecular Function	L-ascorbate:sodium Symporter Activity Sodium-dependent Multivitamin Transmembrane Transporter Activity Nucleobase Transmembrane Transporter Activity L-ascorbic Acid Transporter Activity Sodium-dependent L-ascorbate Transmembrane Transporter Activity
	Biological Process	Nucleobase-containing Compound Metabolic Process Vitamin Metabolic Process Water-soluble Vitamin Metabolic Process Sodium Ion Transport Response To Oxidative Stress Nucleobase Transport L-ascorbic Acid Transport Molecular Hydrogen Transport L-ascorbic Acid Metabolic Process Vitamin Transmembrane Transport Small Molecule Metabolic Process Transepithelial L-ascorbic Acid Transport
Pathways		Metabolism of vitamins and cofactors Defective CD320 causes methylmalonic aciduria Defective GIF causes intrinsic factor deficiency Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF Defective HLCS causes multiple carboxylase deficiency Defective MMAB causes methylmalonic aciduria type cblB Defective BTD causes biotidinase deficiency Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC Defective MTR causes methylmalonic aciduria and homocystinuria type cblG Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD Vitamin C (ascorbate) metabolism Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE Defective MMAA causes methylmalonic aciduria type cblA Defective CUBN causes hereditary megaloblastic anemia 1 Defective AMN causes hereditary megaloblastic anemia 1 Defective MUT causes methylmalonic aciduria mut type Metabolism of water-soluble vitamins and cofactors Defects in biotin (Btn) metabolism Defective TCN2 causes hereditary megaloblastic anemia Defects in cobalamin (B12) metabolism Defects in vitamin and cofactor metabolism
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: AGPAT2 NEDD4
Entrez ID		9962
HPRD ID		04811
Ensembl ID		ENSG00000089057
Uniprot IDs		B4DJZ1 Q9UGH3
PDB IDs
Enriched GO Terms of Interacting Partners?		Transmission Of Virus Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Development Involved In Symbiotic Interaction Progesterone Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Glucocorticoid Receptor Signaling Pathway Protein Targeting To Lysosome CDP-diacylglycerol Biosynthetic Process Negative Regulation Of Sodium Ion Transport CDP-diacylglycerol Metabolic Process Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Protein Localization To Lysosome Receptor Catabolic Process Protein Targeting To Vacuole Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Establishment Of Protein Localization To Vacuole Phosphatidic Acid Biosynthetic Process Phosphatidic Acid Metabolic Process Regulation Of Potassium Ion Transmembrane Transporter Activity Positive Regulation Of Cytokine-mediated Signaling Pathway Positive Regulation Of Response To Cytokine Stimulus Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Protein K63-linked Ubiquitination Positive Regulation Of Signal Transduction Endocardial Cushion Development Regulation Of Potassium Ion Transmembrane Transport Protein Monoubiquitination Receptor Internalization Triglyceride Biosynthetic Process Lysosomal Transport Neuromuscular Junction Development Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Cellular Response To UV Regulation Of Potassium Ion Transport Outflow Tract Morphogenesis Tissue Development Regulation Of Sodium Ion Transport Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of Dendrite Morphogenesis Intracellular Steroid Hormone Receptor Signaling Pathway Vacuolar Transport Receptor Metabolic Process Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of Synapse Organization Regulation Of Synapse Structure Or Activity Cellular Response To Light Stimulus Triglyceride Metabolic Process Negative Regulation Of Ion Transport
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