MAGEC1 and ROCK2

Number of citations of the paper that reports this interaction (PMID 17137291)
8

Data Source:
HPRD (two hybrid)

		MAGEC1	ROCK2
Gene Name		melanoma antigen family C, 1	Rho-associated, coiled-coil containing protein kinase 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleus Centrosome Cytosol Plasma Membrane Spindle Pole Centrosome Cytoplasmic Ribonucleoprotein Granule
	Molecular Function	Protein Binding	Protein Serine/threonine Kinase Activity Structural Molecule Activity Protein Binding ATP Binding Rho GTPase Binding Poly(A) RNA Binding Metal Ion Binding
	Biological Process		Cytokinesis Neural Tube Closure Protein Phosphorylation Smooth Muscle Contraction Rho Protein Signal Transduction Axon Guidance Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Centrosome Duplication Negative Regulation Of Angiogenesis Actin Cytoskeleton Organization Regulation Of Cell Adhesion Regulation Of Actin Cytoskeleton Organization Regulation Of Circadian Rhythm Regulation Of Keratinocyte Differentiation Vascular Endothelial Growth Factor Receptor Signaling Pathway Ephrin Receptor Signaling Pathway Rhythmic Process Dendrite Morphogenesis Centrosome Duplication Regulation Of Stress Fiber Assembly Regulation Of Focal Adhesion Assembly Regulation Of Establishment Of Cell Polarity Regulation Of Cell Motility
Pathways			Signaling by GPCR Axon guidance Semaphorin interactions VEGFA-VEGFR2 Pathway EPHB-mediated forward signaling EPHA-mediated growth cone collapse GPCR downstream signaling Signaling by VEGF EPH-Ephrin signaling G alpha (12/13) signalling events Sema4D in semaphorin signaling Sema4D induced cell migration and growth-cone collapse
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: ATP5L CTAG1B ECHDC2 GTF2F1 H2AFZ MRPL19 ROCK2 RUSC2	3 interactors: MAGEC1 PPP1R12A STAU1
Entrez ID		9947	9475
HPRD ID		02201	04922
Ensembl ID		ENSG00000155495	ENSG00000134318
Uniprot IDs		O60732	O75116
PDB IDs			4L6Q
Enriched GO Terms of Interacting Partners?			Regulation Of Myosin-light-chain-phosphatase Activity Positive Regulation By Virus Of Viral Protein Levels In Host Cell Intracellular MRNA Localization Positive Regulation Of Viral Genome Replication Regulation Of Phosphoprotein Phosphatase Activity
Tagcloud ?		arises bcl1 cdkn1a cldn1 comprises crabp2 ct7 deregulated divide dr6 evi16 fgf7 fibroids fn1 hnrpm isoc1 kgf leiomyoma mapk12 myometrial myometrium occupying regarded rfc sox4 tie1 tnfrsf21 uterine uterus	arthritis autoimmunity balance box collagen diminished disrupted forkhead gammat instrumental kd025 man orphan p3 pharmacological proinflammatory promoters regulates regulatory restore rheumatoid rho rock1 secrete simultaneously stat5 subsets suppressive th17
Tagcloud (Difference) ?		arises bcl1 cdkn1a cldn1 comprises crabp2 ct7 deregulated divide dr6 evi16 fgf7 fibroids fn1 hnrpm isoc1 kgf leiomyoma mapk12 myometrial myometrium occupying regarded rfc sox4 tie1 tnfrsf21 uterine uterus	arthritis autoimmunity balance box collagen diminished disrupted forkhead gammat instrumental kd025 man orphan p3 pharmacological proinflammatory promoters regulates regulatory restore rheumatoid rho rock1 secrete simultaneously stat5 subsets suppressive th17
Tagcloud (Intersection) ?