ROCK2 and MAGEC1

Number of citations of the paper that reports this interaction (PMID 17137291)
8

Data Source:
HPRD (two hybrid)

		ROCK2	MAGEC1
Gene Name		Rho-associated, coiled-coil containing protein kinase 2	melanoma antigen family C, 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Centrosome Cytosol Plasma Membrane Spindle Pole Centrosome Cytoplasmic Ribonucleoprotein Granule
	Molecular Function	Protein Serine/threonine Kinase Activity Structural Molecule Activity Protein Binding ATP Binding Rho GTPase Binding Poly(A) RNA Binding Metal Ion Binding	Protein Binding
	Biological Process	Cytokinesis Neural Tube Closure Protein Phosphorylation Smooth Muscle Contraction Rho Protein Signal Transduction Axon Guidance Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Centrosome Duplication Negative Regulation Of Angiogenesis Actin Cytoskeleton Organization Regulation Of Cell Adhesion Regulation Of Actin Cytoskeleton Organization Regulation Of Circadian Rhythm Regulation Of Keratinocyte Differentiation Vascular Endothelial Growth Factor Receptor Signaling Pathway Ephrin Receptor Signaling Pathway Rhythmic Process Dendrite Morphogenesis Centrosome Duplication Regulation Of Stress Fiber Assembly Regulation Of Focal Adhesion Assembly Regulation Of Establishment Of Cell Polarity Regulation Of Cell Motility
Pathways		Signaling by GPCR Axon guidance Semaphorin interactions VEGFA-VEGFR2 Pathway EPHB-mediated forward signaling EPHA-mediated growth cone collapse GPCR downstream signaling Signaling by VEGF EPH-Ephrin signaling G alpha (12/13) signalling events Sema4D in semaphorin signaling Sema4D induced cell migration and growth-cone collapse
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: MAGEC1 PPP1R12A STAU1	8 interactors: ATP5L CTAG1B ECHDC2 GTF2F1 H2AFZ MRPL19 ROCK2 RUSC2
Entrez ID		9475	9947
HPRD ID		04922	02201
Ensembl ID		ENSG00000134318	ENSG00000155495
Uniprot IDs		O75116	O60732
PDB IDs		4L6Q
Enriched GO Terms of Interacting Partners?		Regulation Of Myosin-light-chain-phosphatase Activity Positive Regulation By Virus Of Viral Protein Levels In Host Cell Intracellular MRNA Localization Positive Regulation Of Viral Genome Replication Regulation Of Phosphoprotein Phosphatase Activity
Tagcloud ?		arthritis autoimmunity balance box collagen diminished disrupted forkhead gammat instrumental kd025 man orphan p3 pharmacological proinflammatory promoters regulates regulatory restore rheumatoid rho rock1 secrete simultaneously stat5 subsets suppressive th17	arises bcl1 cdkn1a cldn1 comprises crabp2 ct7 deregulated divide dr6 evi16 fgf7 fibroids fn1 hnrpm isoc1 kgf leiomyoma mapk12 myometrial myometrium occupying regarded rfc sox4 tie1 tnfrsf21 uterine uterus
Tagcloud (Difference) ?		arthritis autoimmunity balance box collagen diminished disrupted forkhead gammat instrumental kd025 man orphan p3 pharmacological proinflammatory promoters regulates regulatory restore rheumatoid rho rock1 secrete simultaneously stat5 subsets suppressive th17	arises bcl1 cdkn1a cldn1 comprises crabp2 ct7 deregulated divide dr6 evi16 fgf7 fibroids fn1 hnrpm isoc1 kgf leiomyoma mapk12 myometrial myometrium occupying regarded rfc sox4 tie1 tnfrsf21 uterine uterus
Tagcloud (Intersection) ?