BACH1 and PATZ1

Number of citations of the paper that reports this interaction (PMID 10669750)
27

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		BACH1	PATZ1
Gene Name		BTB and CNC homology 1, basic leucine zipper transcription factor 1	POZ (BTB) and AT hook containing zinc finger 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity Heme Binding	DNA Binding Chromatin Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Regulation Of Transcription Involved In G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Spermatogenesis Male Gonad Development T Cell Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Pancreatic cancer ( 22158540) Visceral fat ( 22589738)
Protein-Protein Interactions		11 interactors: ANAPC5 ATF2 DDIT3 HMMR MAFB MAFF MAFG MAFK PATZ1 RBCK1 TP53	6 interactors: BACH1 BACH2 MITF PRKAR1A RNF4 TP53
Entrez ID		571	23598
HPRD ID		04127	05522
Ensembl ID		ENSG00000156273	ENSG00000100105
Uniprot IDs		O14867 Q6ICU0	Q9HBE1
PDB IDs		2IHC	2EPP 2EPQ 2EPR 2EPS 2YT9
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process ER Overload Response Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process RNA Metabolic Process Gene Expression Regulation Of Gene Expression Positive Regulation Of Mitochondrial Membrane Permeability Regulation Of Nitrogen Compound Metabolic Process Blood Coagulation Cellular Macromolecule Biosynthetic Process Hemostasis Macromolecule Biosynthetic Process Negative Regulation Of Cell Cycle Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process T Cell Differentiation Mitotic Cell Cycle Checkpoint Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Regulation Of Mitochondrial Membrane Permeability Regulation Of Body Fluid Levels Regulation Of Membrane Permeability Wound Healing Negative Regulation Of Mitotic Cell Cycle Cell Cycle Checkpoint Lymphocyte Differentiation Regulation Of Epidermal Cell Differentiation Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Response To Wounding Multicellular Organismal Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process T Cell Aggregation T Cell Activation Lymphocyte Aggregation Biosynthetic Process Leukocyte Aggregation Anatomical Structure Development Positive Regulation Of Neuron Apoptotic Process Positive Regulation Of Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Mitochondrial Membrane Organization Leukocyte Cell-cell Adhesion Positive Regulation Of Gene Expression	Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Regulation Of Cell Cycle Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression RNA Metabolic Process Regulation Of Transcription Involved In G2/M Transition Of Mitotic Cell Cycle Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Positive Regulation Of Cellular Biosynthetic Process Cellular Response To Oxygen Levels Positive Regulation Of Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Macromitophagy Regulation Of Kinetochore Assembly Oligodendrocyte Apoptotic Process Double-strand Break Repair DNA Damage Checkpoint Negative Regulation Of Helicase Activity Regulation Of Centromere Complex Assembly Gastrulation Regulation Of Metabolic Process Regulation Of Organelle Organization Regulation Of Cell Cycle Regulation Of Chromosome Organization Nucleobase-containing Compound Metabolic Process Cell Cycle Checkpoint Positive Regulation Of Thymocyte Apoptotic Process Positive Regulation Of Cell Aging Mitochondrial DNA Repair
Tagcloud ?		architectural architecture bach2 bear btb bzip constitutes erythroleukemic globin heterodimer heterodimers holocomplex implicate lcr maf mafk mare mares mel multimeric multivalent nrf1 nucleoprotein obligate opening poz properly zipper	anaplastic anchorage behaviors carcinogenesis carcinomas cytoplasm debated dedifferentiated delocalized differentiated ectopic emerging fact finger histotype increasingly insights invasiveness inverse mesenchymal oncogene opposing papillary poz proceeding restoration suppressor thyroid undifferentiated
Tagcloud (Difference) ?		architectural architecture bach2 bear btb bzip constitutes erythroleukemic globin heterodimer heterodimers holocomplex implicate lcr maf mafk mare mares mel multimeric multivalent nrf1 nucleoprotein obligate opening properly zipper	anaplastic anchorage behaviors carcinogenesis carcinomas cytoplasm debated dedifferentiated delocalized differentiated ectopic emerging fact finger histotype increasingly insights invasiveness inverse mesenchymal oncogene opposing papillary proceeding restoration suppressor thyroid undifferentiated
Tagcloud (Intersection) ?		poz