BACH1

Gene Name		BTB and CNC homology 1, basic leucine zipper transcription factor 1
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity Heme Binding
	Biological Process	Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Regulation Of Transcription Involved In G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Pathways
Drugs
Diseases
GWAS		Pancreatic cancer ( 22158540) Visceral fat ( 22589738)
Protein-protein Interactions		11 interactors: ANAPC5 ATF2 DDIT3 HMMR MAFB MAFF MAFG MAFK PATZ1 RBCK1 TP53
Entrez ID		571
HPRD ID		04127
Ensembl ID		ENSG00000156273
Uniprot IDs		O14867 Q6ICU0
PDB IDs		2IHC
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process ER Overload Response Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process RNA Metabolic Process Gene Expression Regulation Of Gene Expression Positive Regulation Of Mitochondrial Membrane Permeability Regulation Of Nitrogen Compound Metabolic Process Blood Coagulation Cellular Macromolecule Biosynthetic Process Hemostasis Macromolecule Biosynthetic Process Negative Regulation Of Cell Cycle Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process T Cell Differentiation Mitotic Cell Cycle Checkpoint Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Regulation Of Mitochondrial Membrane Permeability Regulation Of Body Fluid Levels Regulation Of Membrane Permeability Wound Healing Negative Regulation Of Mitotic Cell Cycle Cell Cycle Checkpoint Lymphocyte Differentiation Regulation Of Epidermal Cell Differentiation Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Response To Wounding Multicellular Organismal Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process T Cell Aggregation T Cell Activation Lymphocyte Aggregation Biosynthetic Process Leukocyte Aggregation Anatomical Structure Development Positive Regulation Of Neuron Apoptotic Process Positive Regulation Of Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Mitochondrial Membrane Organization Leukocyte Cell-cell Adhesion Positive Regulation Of Gene Expression
Tagcloud ?		architectural architecture bach2 bear btb bzip constitutes erythroleukemic globin heterodimer heterodimers holocomplex implicate lcr maf mafk mare mares mel multimeric multivalent nrf1 nucleoprotein obligate opening poz properly zipper