ZBTB5 and BCOR

Number of citations of the paper that reports this interaction (PubMedID 19491398)
35

Data Source:
BioGRID (affinity chromatography technology, pull down)

		ZBTB5	BCOR
Description		zinc finger and BTB domain containing 5	BCL6 corepressor
Image
GO Annotations	Cellular Component	Chromatin Nucleus	Nucleus Nucleoplasm BCOR Complex
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Transcription Cis-regulatory Region Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Corepressor Activity Ubiquitin-protein Transferase Activity Protein Binding Heat Shock Protein Binding Histone Deacetylase Binding DNA-binding Transcription Factor Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Blastocyst Hatching Chromatin Organization Chromatin Remodeling Heart Development Negative Regulation Of Bone Mineralization Odontogenesis Negative Regulation Of DNA-templated Transcription Roof Of Mouth Development Specification Of Axis Polarity Negative Regulation Of Tooth Mineralization
Pathways
Drugs
Diseases			Anophthalmia and microphthalmia (A/M)
GWAS		Bipolar disorder ( 31043756) Daytime nap ( 33568662)	Pit-and-Fissure caries ( 23470693) Platelet count ( 29403010) Refractive error ( 32231278) Venous thromboembolism ( 31676865)
Interacting Genes		17 interacting genes: BAG4 BCOR CCDC85B DCX EP300 JADE2 METTL5 NCOR1 NCOR2 PPARG PTPN5 RSPH1 SP1 ST3GAL3 SWAP70 TP53 ZBTB7B	16 interacting genes: BCL6 CPNE1 CPNE2 CPNE4 HDAC1 HDAC3 HDAC4 HDAC5 HDAC6 MLLT3 NAA10 NACC1 SP1 UBTD1 USP7 ZBTB5
Entrez ID		9925	54880
HPRD ID		08829	06458
Ensembl ID		ENSG00000168795	ENSG00000183337
Uniprot IDs		O15062 Q5T942	H7BZ37 H7C231 Q6W2J9
PDB IDs		9B9R	2N1L 3BIM 4HPL 6B7G 8HCU
Enriched GO Terms of Interacting Partners?		Histone Deacetylase Binding Rhythmic Process Transcription Repressor Complex Regulation Of MiRNA Transcription Regulation Of MiRNA Metabolic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of MiRNA Transcription Regulation Of Androgen Receptor Signaling Pathway Negative Regulation Of Nucleobase-containing Compound Metabolic Process Transcription Cis-regulatory Region Binding Transcription Coregulator Binding Nuclear Receptor Binding Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of Transcription By RNA Polymerase II RNA Polymerase II-specific DNA-binding Transcription Factor Binding Regulation Of Carbohydrate Catabolic Process STAT Family Protein Binding Regulation Of RNA Metabolic Process Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Purine Nucleotide Metabolic Process Nuclear Retinoid X Receptor Binding Negative Regulation Of Androgen Receptor Signaling Pathway Host-mediated Activation Of Viral Transcription Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Mitochondrion Organization Negative Regulation Of Small Molecule Metabolic Process Circadian Behavior Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Rhythmic Behavior Mononuclear Cell Differentiation Histone Acetyltransferase Complex Regulation Of Small Molecule Metabolic Process Regulation Of Ketone Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Circadian Rhythm Regulation Of Intracellular Signal Transduction Regulation Of Generation Of Precursor Metabolites And Energy Regulation Of Fat Cell Differentiation Regulation Of T-helper 17 Cell Differentiation Host-mediated Perturbation Of Viral Transcription Regulation Of Primary Metabolic Process Chromatin Positive Regulation Of Apoptotic Signaling Pathway DNA Binding T Cell Lineage Commitment Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Leukocyte Differentiation	Histone Deacetylase Activity, Hydrolytic Mechanism Protein Lysine Deacetylase Activity Histone Deacetylase Activity Histone Deacetylase Binding Negative Regulation Of Gene Expression, Epigenetic Histone Deacetylase Complex Protein Deacetylation Transcription Corepressor Binding Negative Regulation Of Myotube Differentiation Epigenetic Regulation Of Gene Expression Macromolecule Deacylation Negative Regulation Of Striated Muscle Cell Differentiation Regulation Of Myotube Differentiation Chromatin Organization Transcription Repressor Complex DNA-binding Transcription Factor Binding Negative Regulation Of Muscle Cell Differentiation Chromatin Remodeling Regulation Of Striated Muscle Cell Differentiation Protein Lysine Delactylase Activity Negative Regulation Of Gene Expression NF-kappaB Binding Negative Regulation Of Macromolecule Biosynthetic Process Protein Decrotonylase Activity Histone Decrotonylase Activity Negative Regulation Of Biosynthetic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Muscle Cell Differentiation Regulation Of DNA-templated Transcription Negative Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Biosynthetic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Negative Regulation Of RNA Metabolic Process Calcium-dependent Phospholipid Binding Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Cell Differentiation RNA Polymerase II-specific DNA-binding Transcription Factor Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Negative Regulation Of Metabolic Process Deacetylase Activity Cellular Response To Parathyroid Hormone Stimulus Cellular Response To Calcium Ion Nucleus Chromatin Binding Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Rhythmic Process Transcription Cis-regulatory Region Binding
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