ZBTB5 and METTL5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZBTB5	METTL5
Description		zinc finger and BTB domain containing 5	methyltransferase 5, N6-adenosine
Image
GO Annotations	Cellular Component	Chromatin Nucleus	Fibrillar Center Nucleus Nucleolus Cytosol Cell Projection Synapse Presynapse Postsynapse
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Nucleic Acid Binding Protein Binding Methyltransferase Activity S-adenosylmethionine-dependent Methyltransferase Activity RRNA (adenine-N6-)-methyltransferase Activity Transferase Activity S-adenosyl-L-methionine Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II	RRNA Processing RRNA Methylation Methylation Positive Regulation Of Translation Stem Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Daytime nap ( 33568662)	Medial orbital frontal cortex volume ( 31530798)
Interacting Genes		17 interacting genes: BAG4 BCOR CCDC85B DCX EP300 JADE2 METTL5 NCOR1 NCOR2 PPARG PTPN5 RSPH1 SP1 ST3GAL3 SWAP70 TP53 ZBTB7B	2 interacting genes: TRMT112 ZBTB5
Entrez ID		9925	29081
HPRD ID		08829	13699
Ensembl ID		ENSG00000168795	ENSG00000138382
Uniprot IDs		O15062 Q5T942	Q9NRN9
PDB IDs		9B9R	6H2U 6H2V
Enriched GO Terms of Interacting Partners?		Histone Deacetylase Binding Rhythmic Process Transcription Repressor Complex Regulation Of MiRNA Transcription Regulation Of MiRNA Metabolic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of MiRNA Transcription Regulation Of Androgen Receptor Signaling Pathway Negative Regulation Of Nucleobase-containing Compound Metabolic Process Transcription Cis-regulatory Region Binding Transcription Coregulator Binding Nuclear Receptor Binding Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of Transcription By RNA Polymerase II RNA Polymerase II-specific DNA-binding Transcription Factor Binding Regulation Of Carbohydrate Catabolic Process STAT Family Protein Binding Regulation Of RNA Metabolic Process Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Purine Nucleotide Metabolic Process Nuclear Retinoid X Receptor Binding Negative Regulation Of Androgen Receptor Signaling Pathway Host-mediated Activation Of Viral Transcription Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Mitochondrion Organization Negative Regulation Of Small Molecule Metabolic Process Circadian Behavior Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Rhythmic Behavior Mononuclear Cell Differentiation Histone Acetyltransferase Complex Regulation Of Small Molecule Metabolic Process Regulation Of Ketone Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Circadian Rhythm Regulation Of Intracellular Signal Transduction Regulation Of Generation Of Precursor Metabolites And Energy Regulation Of Fat Cell Differentiation Regulation Of T-helper 17 Cell Differentiation Host-mediated Perturbation Of Viral Transcription Regulation Of Primary Metabolic Process Chromatin Positive Regulation Of Apoptotic Signaling Pathway DNA Binding T Cell Lineage Commitment Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Leukocyte Differentiation	Peptidyl-glutamine Methylation TRNA Methyltransferase Activator Activity RRNA (guanine-N7)-methylation TRNA (m2G10) Methyltransferase Complex RNA (guanine-N7)-methylation Positive Regulation Of RRNA Processing RRNA Base Methylation Protein Methyltransferase Activity Regulation Of RRNA Processing RRNA Methylation Maturation Of LSU-rRNA RRNA Modification Protein Methylation TRNA Methylation Maturation Of SSU-rRNA Positive Regulation Of Gene Expression, Epigenetic Transcription Initiation-coupled Chromatin Remodeling RNA Methylation TRNA Modification
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?