TMCC2 and IQUB

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TMCC2	IQUB
Gene Name		transmembrane and coiled-coil domain family 2	IQ motif and ubiquitin domain containing
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Membrane	Acrosomal Vesicle Motile Cilium
	Molecular Function	Protein Binding
	Biological Process		Smoothened Signaling Pathway Cilium Morphogenesis
Pathways
Drugs
Diseases
GWAS		Mean platelet volume ( 22139419 19820697) Platelet counts ( 22139419)
Protein-Protein Interactions		26 interactors: AES AMOTL2 APP C6orf165 CCDC33 CDR2 DIP2A DPY30 EIF4E2 FAM161A FAM74A4 FAM90A1 FBF1 HGS HSPD1 IQUB KAT5 PRPF31 PTOV1 RHOXF2 UBA1 WT1-AS ZNF250 ZNF417 ZNF581 ZNF587	17 interactors: BLZF1 CCDC36 DYNLL1 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP12-4 MAGEA6 MDFI SYCE1 TMCC2 TRAF2 TRIM23 TRIM27 TRIM42 TRIM54
Entrez ID		9911	154865
HPRD ID		11040	08194
Ensembl ID		ENSG00000133069	ENSG00000164675
Uniprot IDs		G5E963 O75069	Q8NA54
PDB IDs			2DAF
Enriched GO Terms of Interacting Partners?		Regulation Of Gene Expression Gene Expression RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Regulation Of Metabolic Process Cilium Morphogenesis Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process B Cell Cytokine Production Isotype Switching To IgG Isotypes Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Synaptic Growth At Neuromuscular Junction Positive Regulation Of T Cell Mediated Immune Response To Tumor Cell Cellular Macromolecule Biosynthetic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process Regulation Of ERBB Signaling Pathway Collateral Sprouting In Absence Of Injury Nitrogen Compound Metabolic Process Positive Regulation Of Anoikis Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Nitrogen Compound Metabolic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis	Protein K63-linked Ubiquitination Regulation Of Establishment Of Protein Localization Protein Trimerization Regulation Of Protein Localization Positive Regulation Of JUN Kinase Activity Regulation Of Cellular Localization Regulation Of JUN Kinase Activity Negative Regulation Of Interleukin-2 Secretion Regulation Of Catalytic Activity Positive Regulation Of JNK Cascade Regulation Of Phosphorylation Protein Ubiquitination Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Protein Modification By Small Protein Conjugation Regulation Of Protein Transport Regulation Of Phosphorus Metabolic Process Regulation Of JNK Cascade Protein Polyubiquitination Regulation Of Stress-activated MAPK Cascade Negative Regulation Of Protein Transport Regulation Of Protein Kinase Activity Negative Regulation Of Calcium Ion Import Regulation Of Adaptive Immune Response Positive Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Glial Cell Apoptotic Process Regulation Of Kinase Activity Positive Regulation Of MAP Kinase Activity Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Interferon-gamma Secretion Intracellular Signal Transduction Positive Regulation Of Protein Homodimerization Activity Regulation Of Cellular Component Organization Regulation Of Binding Regulation Of Organelle Organization Cellular Response To Nitric Oxide Activation Of Protein Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Immunoglobulin Secretion Regulation Of MAP Kinase Activity Signal Transduction Response To Nitric Oxide Reproduction Negative Regulation Of Viral Release From Host Cell Regulation Of Protein Phosphorylation Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Trophoblast Giant Cell Differentiation Protein Homotrimerization Positive Regulation Of T Cell Cytokine Production Signaling
Tagcloud ?		apoe apolipoprotein app appl dementin developmental disrupted dmtn drosophila ectopic flies genetically glia glial hypomorphic interacted lethal lethality medulla metabolites microtubule mis named neurodegeneration neuropil orthologue rescued resembling rnai
Tagcloud (Difference) ?		apoe apolipoprotein app appl dementin developmental disrupted dmtn drosophila ectopic flies genetically glia glial hypomorphic interacted lethal lethality medulla metabolites microtubule mis named neurodegeneration neuropil orthologue rescued resembling rnai
Tagcloud (Intersection) ?