CEP350 and ADIPOR1

		CEP350	ADIPOR1
Description		centrosomal protein 350	adiponectin receptor 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Centrosome Centriole Spindle Cytosol Cytoskeleton Membrane Ciliary Basal Body Cell Projection	Plasma Membrane Membrane
	Molecular Function	Protein Binding Microtubule Binding	Protein Binding Protein Kinase Binding Signaling Receptor Activity Identical Protein Binding Metal Ion Binding Adiponectin Binding Adipokinetic Hormone Receptor Activity
	Biological Process	Microtubule Anchoring Protein Localization To Centrosome Non-motile Cilium Assembly	Lipid Metabolic Process Fatty Acid Metabolic Process Hormone-mediated Signaling Pathway Negative Regulation Of Epithelial Cell Migration Negative Regulation Of Epithelial To Mesenchymal Transition Regulation Of Glucose Metabolic Process Regulation Of Lipid Metabolic Process Fatty Acid Oxidation Negative Regulation Of Cell Growth Leptin-mediated Signaling Pathway Adiponectin-activated Signaling Pathway Glucose Homeostasis Negative Regulation Of Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Insulin Receptor Signaling Pathway Positive Regulation Of Cold-induced Thermogenesis Negative Regulation Of Non-canonical NF-kappaB Signal Transduction
Pathways			AMPK inhibits chREBP transcriptional activation activity
Drugs
Diseases
GWAS		Anorexia nervosa ( 23568457) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Smoking initiation ( 30617275)	Mean platelet volume ( 27863252 32888494)
Interacting Genes		7 interacting genes: APP APTX NR1H3 PLEKHA5 PPARA PPARD PPARG	6 interacting genes: APPL1 DPH3 NAA20 NFKBIL1 STK11 TBXA2R
Entrez ID		9857	51094
HPRD ID		09870	06402
Ensembl ID		ENSG00000135837	ENSG00000159346
Uniprot IDs		Q5T2X4 Q5VT06	Q96A54
PDB IDs		2COZ	5LXG 6KRZ 6KS0
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cholesterol Storage Negative Regulation Of Lipid Storage Negative Regulation Of MiRNA Transcription Positive Regulation Of Fatty Acid Metabolic Process Regulation Of Small Molecule Metabolic Process Hormone-mediated Signaling Pathway Regulation Of Lipid Storage Nuclear Receptor Activity Positive Regulation Of Small Molecule Metabolic Process Negative Regulation Of Macrophage Derived Foam Cell Differentiation Regulation Of MiRNA Transcription Regulation Of MiRNA Metabolic Process Regulation Of Fatty Acid Metabolic Process Regulation Of Lipid Metabolic Process Regulation Of Macrophage Derived Foam Cell Differentiation Regulation Of Ketone Metabolic Process RNA Polymerase II Transcription Regulator Complex Positive Regulation Of Lipid Metabolic Process Negative Regulation Of Cell Differentiation Regulation Of Inflammatory Response Negative Regulation Of Inflammatory Response Cellular Response To Oxygen-containing Compound Negative Regulation Of Type II Interferon-mediated Signaling Pathway Intracellular Receptor Signaling Pathway Negative Regulation Of Developmental Process Regulation Of Cell Differentiation Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Defense Response Peroxisome Proliferator Activated Receptor Signaling Pathway Fatty Acid Metabolic Process Regulation Of Type II Interferon-mediated Signaling Pathway Regulation Of Response To Type II Interferon Nuclear Receptor-mediated Signaling Pathway Positive Regulation Of Fatty Acid Oxidation Regulation Of Circadian Rhythm Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Lipid Transport Nuclear Steroid Receptor Activity Regulation Of Defense Response Negative Regulation Of RNA Metabolic Process Response To Nutrient Regulation Of Protein Transport Positive Regulation Of Cholesterol Efflux Negative Regulation Of Myoblast Differentiation Negative Regulation Of Receptor Signaling Pathway Via STAT Negative Regulation Of Cell Growth Sequence-specific DNA Binding Monocarboxylic Acid Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process	Thromboxane Receptor Activity Thromboxane A2 Signaling Pathway Thromboxane A2 Receptor Activity Positive Regulation Of Macropinocytosis Negative Regulation Of Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis N-terminal Peptidyl-glutamine Acetylation NatB Complex N-terminal Peptidyl-aspartic Acid Acetylation N-terminal Peptidyl-glutamic Acid Acetylation Intracellular Protein-containing Complex Protein N-terminal-methionine Acetyltransferase Activity TRNA Wobble Base 5-methoxycarbonylmethyl-2-thiouridinylation Iron Chaperone Activity Protein Localization To Organelle Positive Regulation Of Vesicle Transport Along Microtubule Cellular Response To Lipopolysaccharide LRR Domain Binding Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Protein Localization To Nucleus Macropinosome Protein-N-terminal Amino-acid Acetyltransferase Activity
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