GINS1 and GINS4

Number of citations of the paper that reports this interaction (PMID 21705323)
14

Data Source:
BioGRID (pull down, pull down)

		GINS1	GINS4
Gene Name		GINS complex subunit 1 (Psf1 homolog)	GINS complex subunit 4 (Sld5 homolog)
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Nucleoplasm Cytoplasm
	Molecular Function		Protein Binding
	Biological Process	Mitotic Cell Cycle Inner Cell Mass Cell Proliferation DNA Strand Elongation Involved In DNA Replication	Mitotic Cell Cycle Inner Cell Mass Cell Proliferation DNA Strand Elongation Involved In DNA Replication
Pathways		Synthesis of DNA S Phase DNA strand elongation Cell Cycle, Mitotic Unwinding of DNA	Synthesis of DNA S Phase DNA strand elongation Cell Cycle, Mitotic Unwinding of DNA
Drugs
Diseases
GWAS		Liver enzyme levels (alkaline phosphatase) ( 22001757)
Protein-Protein Interactions		2 interactors: GINS3 GINS4	6 interactors: GINS1 GINS2 GINS3 POLA1 POLD1 POLE
Entrez ID		9837	84296
HPRD ID		11067	11583
Ensembl ID		ENSG00000101003	ENSG00000147536
Uniprot IDs		Q14691	Q9BRT9
PDB IDs		2E9X 2EHO 2Q9Q	2E9X 2EHO 2Q9Q
Enriched GO Terms of Interacting Partners?		DNA Replication Inner Cell Mass Cell Proliferation DNA Metabolic Process Blastocyst Growth DNA Strand Elongation Involved In DNA Replication DNA Strand Elongation Blastocyst Development DNA-dependent DNA Replication	DNA Replication DNA-dependent DNA Replication DNA Strand Elongation Involved In DNA Replication DNA Strand Elongation DNA Metabolic Process Telomere Maintenance Via Semi-conservative Replication Nuclear DNA Replication Telomere Maintenance Via Recombination Mitotic Recombination Telomere Maintenance Via Telomere Lengthening Mitotic Cell Cycle Base-excision Repair, Gap-filling Telomere Maintenance DNA Biosynthetic Process Cell Cycle DNA Synthesis Involved In DNA Repair Nucleotide-excision Repair, DNA Gap Filling Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process DNA Recombination DNA Replication Initiation Transcription-coupled Nucleotide-excision Repair Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Base-excision Repair Nitrogen Compound Metabolic Process Nucleotide-excision Repair DNA Replication Proofreading DNA Repair Cellular Homeostasis Leading Strand Elongation G1/S Transition Of Mitotic Cell Cycle Cellular Response To DNA Damage Stimulus Lagging Strand Elongation Chromosome Organization Cell Cycle Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition DNA Replication, Synthesis Of RNA Primer Homeostatic Process Fatty Acid Homeostasis Cellular Response To Stress Double-strand Break Repair Via Nonhomologous End Joining Inner Cell Mass Cell Proliferation Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Cellular Metabolic Process In Utero Embryonic Development
Tagcloud ?		annotations birc5 cdca2 cdh3 cited1 dhfr esco2 gins4 hells mc1r melana melanocyte melanocytes melk msg ncapg ncapg2 ncaph nusap1 oca2 pax3 pbk rad54l recapitulate revolutionized segregating subclasses tyms unsupervised	annotations birc5 cdca2 cdh3 cited1 dhfr esco2 gins1 hells mc1r melana melanocyte melanocytes melk msg ncapg ncapg2 ncaph nusap1 oca2 pax3 pbk rad54l recapitulate revolutionized segregating subclasses tyms unsupervised
Tagcloud (Difference) ?
Tagcloud (Intersection) ?		annotations birc5 cdca2 cdh3 cited1 dhfr esco2 gins1 gins4 hells mc1r melana melanocyte melanocytes melk msg ncapg ncapg2 ncaph nusap1 oca2 pax3 pbk rad54l recapitulate revolutionized segregating subclasses tyms unsupervised