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DHX38 and CDC40
Number of citations of the paper that reports this interaction (PMID
9524131
)
29
Data Source:
HPRD
(in vitro)
DHX38
CDC40
Gene Name
DEAH (Asp-Glu-Ala-His) box polypeptide 38
cell division cycle 40
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Membrane
Catalytic Step 2 Spliceosome
Nucleoplasm
Spliceosomal Complex
Catalytic Step 2 Spliceosome
Molecular Function
ATP-dependent RNA Helicase Activity
Protein Binding
ATP Binding
Poly(A) RNA Binding
Protein Binding
Poly(A) RNA Binding
Biological Process
MRNA Splicing, Via Spliceosome
Transcription From RNA Polymerase II Promoter
Termination Of RNA Polymerase II Transcription
MRNA Export From Nucleus
RNA Splicing
Gene Expression
MRNA 3'-end Processing
MRNA Splicing, Via Spliceosome
Transcription From RNA Polymerase II Promoter
Termination Of RNA Polymerase II Transcription
MRNA Export From Nucleus
RNA Splicing
Gene Expression
MRNA 3'-end Processing
Pathways
mRNA Splicing
Processing of Capped Intron-Containing Pre-mRNA
RNA Polymerase II Transcription
Transport of Mature mRNA derived from an Intron-Containing Transcript
mRNA Splicing - Major Pathway
Transport of Mature Transcript to Cytoplasm
Cleavage of Growing Transcript in the Termination Region
RNA Polymerase II Transcription Termination
mRNA 3'-end processing
mRNA Splicing
Processing of Capped Intron-Containing Pre-mRNA
RNA Polymerase II Transcription
Transport of Mature mRNA derived from an Intron-Containing Transcript
mRNA Splicing - Major Pathway
Transport of Mature Transcript to Cytoplasm
Cleavage of Growing Transcript in the Termination Region
RNA Polymerase II Transcription Termination
mRNA 3'-end processing
Drugs
Diseases
GWAS
Cholesterol, total (
20686565
)
LDL cholesterol (
20686565
)
Metabolite levels (
22916037
)
Protein-Protein Interactions
6 interactors:
CDC40
CSNK2A1
MFAP1
PPP4C
TERF2IP
U2AF1
3 interactors:
DHX38
SMAD2
SMURF1
Entrez ID
9785
51362
HPRD ID
05720
05721
Ensembl ID
ENSG00000140829
ENSG00000168438
Uniprot IDs
Q92620
O60508
PDB IDs
Enriched GO Terms of Interacting Partners
?
Regulation Of Double-strand Break Repair Via Homologous Recombination
Regulation Of Double-strand Break Repair
Termination Of RNA Polymerase II Transcription
Regulation Of DNA Repair
MRNA Export From Nucleus
Regulation Of DNA Recombination
DNA-templated Transcription, Termination
RNA Export From Nucleus
MRNA 3'-end Processing
Negative Regulation Of Chromosome Organization
Negative Regulation Of DNA Recombination At Telomere
RNA 3'-end Processing
Nuclear Export
MRNA Transport
Regulation Of Response To DNA Damage Stimulus
RNA Transport
RNA Localization
Regulation Of Chromosome Organization
Transcription, DNA-templated
Protection From Non-homologous End Joining At Telomere
RNA Biosynthetic Process
MRNA Splicing, Via Spliceosome
Telomere Capping
Protein Localization To Chromosome, Telomeric Region
RNA Splicing, Via Transesterification Reactions
Nucleocytoplasmic Transport
Nuclear Transport
Telomere Maintenance Via Telomerase
Negative Regulation Of Telomere Maintenance
RNA Splicing
RNA Metabolic Process
MRNA Processing
Regulation Of Telomere Maintenance
Gene Expression
RNA-dependent DNA Replication
Negative Regulation Of DNA Recombination
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
MRNA Metabolic Process
Protein Localization To Chromosome
Telomere Maintenance Via Telomere Lengthening
RNA Processing
Mitotic Spindle Checkpoint
NIK/NF-kappaB Signaling
Negative Regulation Of Chromosome Segregation
Cytoplasmic Transport
Spindle Checkpoint
Regulation Of Mitotic Sister Chromatid Separation
Negative Regulation Of Mitotic Nuclear Division
Regulation Of Mitotic Metaphase/anaphase Transition
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of BMP Signaling Pathway
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Nuclear Export
Transforming Growth Factor Beta Receptor Signaling Pathway
Cellular Response To Transforming Growth Factor Beta Stimulus
Regulation Of Cellular Response To Growth Factor Stimulus
Response To Transforming Growth Factor Beta
Positive Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry
Zygotic Specification Of Dorsal/ventral Axis
Nucleocytoplasmic Transport
Nuclear Transport
Establishment Of Localization In Cell
Positive Regulation Of Mesoderm Development
Primary MiRNA Processing
Ubiquitin-dependent SMAD Protein Catabolic Process
Regulation Of Nodal Signaling Pathway
Common-partner SMAD Protein Phosphorylation
Positive Regulation Of Activin Receptor Signaling Pathway
Cellular Localization
SMAD Protein Complex Assembly
Paraxial Mesoderm Morphogenesis
RNA Processing
Cellular Response To Growth Factor Stimulus
Response To Growth Factor
Nodal Signaling Pathway
Protein Localization To Cell Surface
Receptor Catabolic Process
Cytoplasmic Transport
Production Of MiRNAs Involved In Gene Silencing By MiRNA
Embryonic Foregut Morphogenesis
Foregut Morphogenesis
Regulation Of Activin Receptor Signaling Pathway
Paraxial Mesoderm Development
Response To Cholesterol
Dorsal/ventral Axis Specification
Ectoderm Development
Pericardium Development
Activin Receptor Signaling Pathway
Positive Regulation Of Epithelial To Mesenchymal Transition
Signal Transduction Involved In Regulation Of Gene Expression
Transcription From RNA Polymerase II Promoter
Enzyme Linked Receptor Protein Signaling Pathway
Gene Silencing By MiRNA
Cellular Response To DsRNA
Positive Regulation Of BMP Signaling Pathway
Tagcloud
?
18s
actb
ap3d1
bestkeeper
c2c12
csnk2a2
dystrophic
dystrophin
exceptionally
fbxo38
fbxw2
gapdh
genorm
h2k2b4
h2ksf1
htatsf1
informative
mef2c
myoblasts
myod
myogenesis
myogenic
myogenin
normalization
normalizing
normfinder
packages
pak1ip1
zfp91
Tagcloud (Difference)
?
18s
actb
ap3d1
bestkeeper
c2c12
csnk2a2
dystrophic
dystrophin
exceptionally
fbxo38
fbxw2
gapdh
genorm
h2k2b4
h2ksf1
htatsf1
informative
mef2c
myoblasts
myod
myogenesis
myogenic
myogenin
normalization
normalizing
normfinder
packages
pak1ip1
zfp91
Tagcloud (Intersection)
?