CDC40 and MIR106B

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		CDC40	MIR106B
Description		cell division cycle 40	microRNA 106b
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Nuclear Speck U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome	Extracellular Space RISC Complex Extracellular Vesicle
	Molecular Function	RNA Binding MRNA Binding Protein Binding	MRNA 3'-UTR Binding MRNA Base-pairing Post-transcriptional Repressor Activity
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Embryonic Brain Development	Negative Regulation Of Gene Expression Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Angiogenesis Negative Regulation Of Interleukin-8 Production MiRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Gene Silencing By Inhibition Of Translation MiRNA-mediated Gene Silencing By MRNA Destabilization Cellular Response To Hypoxia Cellular Response To Amyloid-beta Regulation Of Endothelial Cell Apoptotic Process
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Daytime sleep phenotypes ( 27126917)
Interacting Genes		9 interacting genes: CRYAA DHX38 EPS15 MIR106B MIRLET7A2 MIRLET7E MIRLET7G SMAD2 SMURF1	97 interacting genes: AIMP1 AQR C1QBP CCAR1 CDC40 CDC5L CELF1 CHERP CPSF1 DARS1 DDX1 DDX21 DDX23 DDX3X DDX3Y DHX36 DHX37 EDC4 EIF2AK2 EPRS1 ERAL1 ESRP1 FUS G3BP2 GRSF1 HARS2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI2 NOL6 NONO NUDT21 NUFIP2 PDCD11 PGAM5 PLRG1 PRMT1 PTBP1 PTBP3 PUF60 PUM1 PURA QARS1 RARS1 RBM10 RBM14 RBM17 RBM4 RTCA RTCB SF1 SF3A1 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 SUGP2 SYNCRIP TAF15 TIAL1 TRA2A TRA2B U2SURP UPF1 UTP20 XAB2 YBX1 YBX2 YBX3 ZFR ZNF346
Entrez ID		51362	406900
HPRD ID		05721
Ensembl ID		ENSG00000168438	ENSG00000208036
Uniprot IDs		O60508
PDB IDs		5MQF 5XJC 5YZG 5Z56 5Z57 6FF4 6FF7 6ICZ 6ID0 6ID1 6QDV 6ZYM 7A5P 7AAV 7ABI 7W59 7W5A 7W5B 8C6J 8CH6 8I0T 8I0U 8I0V 8I0W 8RO2 9FMD
Enriched GO Terms of Interacting Partners?		RISC Complex MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Negative Regulation Of Gene Expression Negative Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Transforming Growth Factor Beta Receptor Binding I-SMAD Binding Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway R-SMAD Binding Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell MiRNA-mediated Gene Silencing By MRNA Destabilization Post-transcriptional Regulation Of Gene Expression SMAD Binding Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Engulfment Of Target By Autophagosome Negative Regulation Of Biosynthetic Process Regulation Of Cellular Response To Growth Factor Stimulus Homomeric SMAD Protein Complex Negative Regulation Of Macromolecule Metabolic Process MRNA Destabilization Zygotic Specification Of Dorsal/ventral Axis Activin Responsive Factor Complex Paraxial Mesoderm Morphogenesis Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway RNA Destabilization Regulation Of BMP Signaling Pathway Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Metabolic Process Response To Glucose Embryonic Organ Morphogenesis Regulation Of Macromolecule Metabolic Process Response To Monosaccharide Mesoderm Morphogenesis Positive Regulation Of Cell Growth Lens Fiber Cell Morphogenesis Ubiquitin-dependent Endocytosis Clathrin Coat Of Coated Pit Response To Carbohydrate Odontoblast Differentiation SMAD Protein Complex Pericardium Development Trophoblast Cell Migration 3'-5' RNA Helicase Activity Activin Receptor Binding Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Catabolic Process	RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process RNA Splicing MRNA Processing MRNA Metabolic Process Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Binding Spliceosomal Complex Catalytic Step 2 Spliceosome Nucleoplasm Macromolecule Metabolic Process Regulation Of RNA Splicing Regulation Of MRNA Metabolic Process Nucleus Post-transcriptional Regulation Of Gene Expression Aminoacyl-tRNA Synthetase Multienzyme Complex Ribonucleoprotein Complex Cytoplasmic Stress Granule MiRNA Binding Negative Regulation Of MRNA Metabolic Process MRNA 3'-UTR Binding Regulation Of MRNA Processing Regulation Of Translation Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Catabolic Process TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity Negative Regulation Of MRNA Catabolic Process Regulation Of RNA Stability RNA Stabilization TRNA Aminoacylation Negative Regulation Of Translation MRNA Stabilization Regulation Of MRNA Stability Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Protein-RNA Complex Assembly Ligase Activity U2 SnRNP Spliceosomal Complex Assembly RNA Helicase Activity Nucleolus Positive Regulation Of Cytoplasmic Translation TRNA Metabolic Process Regulation Of Macromolecule Metabolic Process
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