DHX38

Gene Name		DEAH (Asp-Glu-Ala-His) box polypeptide 38
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Membrane Catalytic Step 2 Spliceosome
	Molecular Function	ATP-dependent RNA Helicase Activity Protein Binding ATP Binding Poly(A) RNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Export From Nucleus RNA Splicing Gene Expression MRNA 3'-end Processing
Pathways		mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway Transport of Mature Transcript to Cytoplasm Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination mRNA 3'-end processing
Drugs
Diseases
GWAS		Cholesterol, total ( 20686565) LDL cholesterol ( 20686565) Metabolite levels ( 22916037)
Protein-protein Interactions		6 interactors: CDC40 CSNK2A1 MFAP1 PPP4C TERF2IP U2AF1
Entrez ID		9785
HPRD ID		05720
Ensembl ID		ENSG00000140829
Uniprot IDs		Q92620
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Double-strand Break Repair Termination Of RNA Polymerase II Transcription Regulation Of DNA Repair MRNA Export From Nucleus Regulation Of DNA Recombination DNA-templated Transcription, Termination RNA Export From Nucleus MRNA 3'-end Processing Negative Regulation Of Chromosome Organization Negative Regulation Of DNA Recombination At Telomere RNA 3'-end Processing Nuclear Export MRNA Transport Regulation Of Response To DNA Damage Stimulus RNA Transport RNA Localization Regulation Of Chromosome Organization Transcription, DNA-templated Protection From Non-homologous End Joining At Telomere RNA Biosynthetic Process MRNA Splicing, Via Spliceosome Telomere Capping Protein Localization To Chromosome, Telomeric Region RNA Splicing, Via Transesterification Reactions Nucleocytoplasmic Transport Nuclear Transport Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance RNA Splicing RNA Metabolic Process MRNA Processing Regulation Of Telomere Maintenance Gene Expression RNA-dependent DNA Replication Negative Regulation Of DNA Recombination Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process MRNA Metabolic Process Protein Localization To Chromosome Telomere Maintenance Via Telomere Lengthening RNA Processing Mitotic Spindle Checkpoint NIK/NF-kappaB Signaling Negative Regulation Of Chromosome Segregation Cytoplasmic Transport Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Metaphase/anaphase Transition
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