RASSF2 and RASSF5

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, pull down, affinity chromatography technology)

		RASSF2	RASSF5
Description		Ras association domain family member 2	Ras association domain family member 5
Image		No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Nucleus Nucleoplasm Chromosome Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Protein-containing Complex	Nucleus Cytoplasm Cytoskeleton Microtubule
	Molecular Function	Protein Kinase Activity Protein Binding	Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Skeletal System Development Ossification Signal Transduction Canonical NF-kappaB Signal Transduction Positive Regulation Of Protein Autophosphorylation Negative Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Apoptotic Process Regulation Of Osteoblast Differentiation Regulation Of Osteoclast Differentiation Positive Regulation Of Protein Kinase Activity Positive Regulation Of JNK Cascade Bone Remodeling Homeostasis Of Number Of Cells Protein Stabilization Regulation Of Non-canonical NF-kappaB Signal Transduction Negative Regulation Of Non-canonical NF-kappaB Signal Transduction	Apoptotic Process Signal Transduction Positive Regulation Of Protein Ubiquitination Lymphocyte Proliferation Negative Regulation Of Lymphocyte Proliferation Regulation Of Protein Localization To Nucleus
Pathways
Drugs
Diseases
GWAS		Refractive error ( 32231278) Suicide attempt severity in mood disorders ( 33783297) Systemic lupus erythematosus ( 24871463)	Inflammatory bowel disease ( 23128233) Late-onset Alzheimer's disease ( 27770636) Neurofibrillary tangles ( 25188341)
Interacting Genes		8 interacting genes: HRAS KDM1A KRAS PRMT3 PRMT6 RASSF5 S100Z SUV39H1	30 interacting genes: ADH6 AMOTL2 APPBP2 BTRC HRAS KRAS KRT40 KRTAP4-2 LSM7 MRAS MYLIP NRAS RABIF RALA RAP1B RAP2A RAP2B RASSF1 RASSF2 REL RRAS RRAS2 SMAD4 STK4 TERF2IP TRAF1 TRAF2 UBQLN1 UBQLN2 VPS28
Entrez ID		9770	83593
HPRD ID		15218	06117
Ensembl ID		ENSG00000101265	ENSG00000266094
Uniprot IDs		P50749	A8K5F3 Q8WWW0
PDB IDs			4LGD 4OH8
Enriched GO Terms of Interacting Partners?		Histone Methyltransferase Activity Protein-arginine Omega-N Monomethyltransferase Activity Histone H4R3 Methyltransferase Activity Glial Cell Development Protein-arginine Omega-N Asymmetric Methyltransferase Activity Protein-arginine N-methyltransferase Activity Regulation Of Multicellular Organismal Process Histone H3 Methyltransferase Activity Cellular Response To Gamma Radiation Regulation Of Long-term Neuronal Synaptic Plasticity Methyltransferase Activity Protein-membrane Adaptor Activity Methylation Regulation Of Protein Ubiquitination Regulation Of Neuronal Synaptic Plasticity Response To Gamma Radiation Positive Regulation Of Gene Expression MAPK Cascade Regulation Of Cellular Senescence Positive Regulation Of Neurogenesis Positive Regulation Of Nervous System Development Ventral Spinal Cord Interneuron Fate Determination Type B Pancreatic Cell Fate Commitment Chromatin Remodeling Epigenetic Regulation Of Gene Expression Regulation Of Post-translational Protein Modification Histone H2AR3 Methyltransferase Activity Cellular Senescence Positive Regulation Of Gliogenesis Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription GDP Binding G Protein Activity Regulation Of Macromolecule Metabolic Process Cellular Response To Ionizing Radiation Regulation Of RNA Biosynthetic Process GTPase Complex Ras Protein Signal Transduction Regulation Of Multicellular Organismal Development Pancreatic A Cell Fate Commitment Pancreatic PP Cell Fate Commitment Negative Regulation Of Retinoic Acid Biosynthetic Process Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity Histone H3R2 Methyltransferase Activity Regulation Of Cell Development Regulation Of Neurogenesis Chromatin Organization Positive Regulation Of Cell Population Proliferation Phospholipase C Activator Activity	GDP Binding Intracellular Signaling Cassette Small GTPase-mediated Signal Transduction Intracellular Signal Transduction G Protein Activity Ras Protein Signal Transduction GTPase Activity GTP Binding Signal Transduction Cytosol Rap Protein Signal Transduction Regulation Of Intracellular Signal Transduction Protein-containing Complex Binding Regulation Of Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Schwann Cell Migration Regulation Of Signal Transduction Regulation Of Protein Modification Process Regulation Of MAPK Cascade Non-canonical NF-kappaB Signal Transduction Regulation Of Protein Catabolic Process Positive Regulation Of Signal Transduction Regulation Of Cell Communication Regulation Of Signaling Branching Morphogenesis Of An Epithelial Tube Nucleotide Binding Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Cell Communication Positive Regulation Of Signaling Regulation Of JNK Cascade Thioesterase Binding Morphogenesis Of A Branching Epithelium Morphogenesis Of A Branching Structure Regulation Of Canonical NF-kappaB Signal Transduction Cytoplasmic Vesicle Membrane Morphogenesis Of An Epithelium Hydrolase Activity Macromolecule Catabolic Process Positive Regulation Of Macromolecule Metabolic Process Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of NF-kappaB Transcription Factor Activity Modification-dependent Protein Catabolic Process Regulation Of Protein Stability Positive Regulation Of Protein Modification Process Positive Regulation Of ERAD Pathway Positive Regulation Of Protein Catabolic Process Bounding Membrane Of Organelle Regulation Of Protein Phosphorylation Regulation Of Glial Cell Migration Autophagosome Assembly
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?