CCP110 and CETN2

Number of citations of the paper that reports this interaction (PMID 16760425)
22

Data Source:
HPRD (in vivo, two hybrid)

		CCP110	CETN2
Gene Name		centriolar coiled coil protein 110kDa	centrin, EF-hand protein, 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Centrosome Centriole Cytosol Protein Complex	Intracellular Centrosome Centriole Cytosol Photoreceptor Connecting Cilium Ciliary Basal Body XPC Complex
	Molecular Function	Protein Binding	Calcium Ion Binding Protein Binding Microtubule Binding G-protein Beta/gamma-subunit Complex Binding Heterotrimeric G-protein Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization Centriole Replication Cell Projection Organization Regulation Of Cytokinesis Centrosome Duplication	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Nucleotide-excision Repair Organelle Organization Mitotic Nuclear Division Centriole Replication Spermatogenesis Regulation Of Cytokinesis Cell Division
Pathways		Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic	Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: AKAP9 CALM1 CALM3 CDK1 CDK2 CEP97 CETN1 CETN2 PCNT PNMA1 TFIP11 USP33	8 interactors: ARSA CCP110 PNMA5 POC5 PRMT6 SFI1 SGSM1 XPC
Entrez ID		9738	1069
HPRD ID		10848	02051
Ensembl ID		ENSG00000103540
Uniprot IDs		B4DTZ1 O43303	P41208
PDB IDs			1M39 1ZMZ 2A4J 2GGM 2K2I 2OBH
Enriched GO Terms of Interacting Partners?		G2/M Transition Of Mitotic Cell Cycle Centrosome Cycle Organelle Organization Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Centrosome Organization Cell Cycle Process Microtubule Organizing Center Organization Mitotic Cell Cycle Process Centrosome Duplication Mitotic Cell Cycle Cell Cycle Microtubule Cytoskeleton Organization Response To Amine Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Positive Regulation Of Ion Transmembrane Transporter Activity Positive Regulation Of Transporter Activity Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Cytokinesis Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Regulation Of Heart Rate Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Positive Regulation Of Ion Transmembrane Transport Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Mitotic Nuclear Division Vascular Endothelial Growth Factor Receptor Signaling Pathway Detection Of Calcium Ion Positive Regulation Of Transport Regulation Of Cell Communication By Electrical Coupling Positive Regulation Of Phosphoprotein Phosphatase Activity Microtubule-based Process Positive Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Protein Autophosphorylation Positive Regulation Of Nitric-oxide Synthase Activity Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Glycogen Catabolic Process Negative Regulation Of Peptidyl-threonine Phosphorylation Cell Division Regulation Of Voltage-gated Calcium Channel Activity Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Positive Regulation Of Protein Dephosphorylation Negative Regulation Of Cation Channel Activity Regulation Of Intracellular Transport Response To Stress Regulation Of Cell Cycle Polysaccharide Catabolic Process Positive Regulation Of Monooxygenase Activity Response To Inorganic Substance	Cell Cycle Nucleotide-excision Repair, DNA Damage Recognition Histone H3-R2 Methylation G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Process Mitotic Cell Cycle Organelle Organization Protein Insertion Into ER Membrane Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Response To Methylmercury Intra-S DNA Damage Checkpoint Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Cell Cycle Process
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