CCP110 and CEP97

Number of citations of the paper that reports this interaction (PubMedID 17719545)
0

Data Source:
HPRD (in vitro, in vivo)

		CCP110	CEP97
Description		centriolar coiled-coil protein 110	centrosomal protein 97
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Centriole Microtubule Organizing Center Cytosol Cytoskeleton Cilium Protein-containing Complex Cell Projection	Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Protein-containing Complex
	Molecular Function	Protein Binding	Protein Binding Calmodulin Binding
	Biological Process	Centriole Replication Cell Projection Organization Ciliary Basal Body Organization Regulation Of Cytokinesis Positive Regulation Of Cilium Assembly Centrosome Duplication Negative Regulation Of Cilium Assembly	Cell Projection Organization Regulation Of Mitotic Spindle Assembly Negative Regulation Of Cilium Assembly
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane Ub-specific processing proteases AURKA Activation by TPX2 RHOV GTPase cycle	Anchoring of the basal body to the plasma membrane RHOV GTPase cycle
Drugs
Diseases
GWAS
Interacting Genes		14 interacting genes: AKAP9 CALM1 CALM3 CDK1 CDK2 CEP97 CETN1 CETN2 DCAF1 PCNT PNMA1 TFIP11 USP33 USP7	2 interacting genes: CCP110 PTEN
Entrez ID		9738	79598
HPRD ID		10848	08014
Ensembl ID		ENSG00000103540	ENSG00000182504
Uniprot IDs		O43303	A0A994J4L0 A0A994J522 A0A994J7E5 B4DGU8 E9PG22 Q8IW35
PDB IDs
Enriched GO Terms of Interacting Partners?		Centrosome Cytoskeleton G2/M Transition Of Mitotic Cell Cycle Cell Cycle G2/M Phase Transition Negative Regulation Of High Voltage-gated Calcium Channel Activity Microtubule Organizing Center Organization Centriole Replication Cytoplasm Regulation Of Cardiac Muscle Cell Action Potential Cyclin-dependent Protein Kinase Activity Centriole Assembly VCB Complex Mitotic Cell Cycle Phase Transition Spindle Microtubule Negative Regulation Of Calcium Ion Export Across Plasma Membrane Adenylate Cyclase Activator Activity Transporter Inhibitor Activity Regulation Of Calcium Ion Export Across Plasma Membrane Cell Cycle Phase Transition Histone Kinase Activity Centriole Protection From Non-homologous End Joining At Telomere Heterotrimeric G-protein Binding Regulation Of Action Potential Negative Regulation Of Voltage-gated Calcium Channel Activity Regulation Of Cell Cycle Process DNA Metabolic Process Microtubule Cytoskeleton Organization Microtubule-based Process Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Voltage-gated Potassium Channel Complex Post-translational Protein Modification Titin Binding Regulation Of Cytokinesis Telomere Maintenance In Response To DNA Damage Regulation Of Voltage-gated Calcium Channel Activity Detection Of Calcium Ion Organelle Organization Microtubule Organizing Center Protein Deubiquitination Regulation Of Cell Communication By Electrical Coupling Regulation Of Heart Rate Protein Phosphatase Activator Activity Calyx Of Held Centrosome Duplication Protein Modification By Small Protein Removal G-protein Beta/gamma-subunit Complex Binding Regulation Of Cell Cycle Catalytic Complex Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion	Negative Regulation Of Synaptic Vesicle Clustering Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Membraneless Organelle Assembly Negative Regulation Of Cell Projection Organization Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Central Nervous System Myelin Maintenance Rhythmic Synaptic Transmission Locomotor Rhythm Regulation Of Plasma Membrane Bounded Cell Projection Organization Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase Activity Myelin Sheath Adaxonal Region Regulation Of Cell Projection Organization Phosphatidylinositol-3-phosphate Phosphatase Activity Cellular Response To Electrical Stimulus Ubiquitin Ligase Activator Activity Spindle Assembly Involved In Female Meiosis Negative Regulation Of Peptidyl-serine Phosphorylation Regulation Of Synaptic Vesicle Clustering Postsynaptic Specialization Assembly Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Prepulse Inhibition Neuron-neuron Synaptic Transmission Phosphatidylinositol Phosphate Phosphatase Activity Meiotic Spindle Assembly Synapse Maturation Negative Regulation Of Cell Size Maternal Behavior Organelle Assembly Presynaptic Membrane Organization Negative Regulation Of Cellular Component Organization Schmidt-Lanterman Incisure Myelin Maintenance Negative Regulation Of Epithelial Cell Migration Anaphase-promoting Complex Binding Postsynaptic Density Assembly Regulation Of Cell Cycle Process Forebrain Morphogenesis Negative Regulation Of Excitatory Postsynaptic Potential Presynaptic Membrane Assembly Parental Behavior Ciliary Basal Body Organization Postsynaptic Density Organization Negative Regulation Of Focal Adhesion Assembly Microtubule-based Process Dendritic Spine Morphogenesis Ubiquitin-specific Protease Binding Centrosome Duplication Plasma Membrane Bounded Cell Projection Organization
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