PIGR

Gene Name		polymeric immunoglobulin receptor
Image
Gene Ontology Annotations	Cellular Component	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Receptor Complex Extracellular Vesicular Exosome
	Molecular Function	Polymeric Immunoglobulin Receptor Activity
	Biological Process	Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste Retina Homeostasis Immunoglobulin Transcytosis In Epithelial Cells Mediated By Polymeric Immunoglobulin Receptor Epidermal Growth Factor Receptor Signaling Pathway Fc Receptor Signaling Pathway Receptor Clustering
Pathways
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233)
Protein-protein Interactions		4 interactors: AP1M1 CCL5 CD79A RAB3B
Entrez ID		5284
HPRD ID		01436
Ensembl ID		ENSG00000162896
Uniprot IDs		P01833
PDB IDs		1XED 2OCW 3CHN 3CM9
Enriched GO Terms of Interacting Partners?		Immune System Process Regulation Of Vesicle Size Positive Regulation Of Ion Transport Peptidyl-cysteine Methylation Negative Regulation Of Macrophage Apoptotic Process Regulation Of Immune System Process Positive Regulation Of Dopamine Uptake Involved In Synaptic Transmission Positive Regulation Of Cell-cell Adhesion Mediated By Integrin Positive Regulation Of Natural Killer Cell Chemotaxis Negative Regulation Of Chemokine-mediated Signaling Pathway Antigen Processing And Presentation Vesicle-mediated Transport Positive Regulation Of Activation Of JAK2 Kinase Activity Positive Regulation Of Activation Of Janus Kinase Activity Exocytosis Positive Regulation Of Macrophage Chemotaxis Pigment Granule Maturation Endosome To Melanosome Transport Eosinophil Chemotaxis Eosinophil Migration Regulation Of Dopamine Uptake Involved In Synaptic Transmission Positive Regulation Of T Cell Chemotaxis Regulation Of Cell-cell Adhesion Mediated By Integrin Positive Regulation Of Synaptic Transmission, Dopaminergic Cellular Pigment Accumulation Negative Regulation By Host Of Viral Transcription Positive Regulation Of Monocyte Chemotaxis Regulation Of Chronic Inflammatory Response Establishment Of Localization In Cell Regulation Of Macrophage Chemotaxis Regulation Of Monocyte Chemotaxis Positive Regulation Of Translational Initiation Dendritic Cell Chemotaxis Leukocyte Activation Activation Of Phospholipase D Activity Regulation Of Neurotransmitter Uptake Positive Regulation Of T Cell Apoptotic Process Monocyte Chemotaxis Regulation Of Macrophage Apoptotic Process Secretion By Cell Positive Regulation Of Cell Adhesion Mediated By Integrin Macrophage Chemotaxis Extracellular Negative Regulation Of Signal Transduction Positive Regulation Of T Cell Migration Regulation Of Synaptic Transmission, Dopaminergic Negative Regulation Of Myeloid Cell Apoptotic Process Positive Regulation Of Lymphocyte Apoptotic Process Regulation Of T Cell Migration Negative Regulation Of Viral Transcription Melanosome Organization
Tagcloud ?		adenoids belonging defense degranulation destructive dimers eosinophils extravasation glandular helper iga ige immunopathology leukocytes migrate mucosa penetrating perhaps piga polymers priming reaches secretions secretory th2 tonsils transported unsuccessful