EEF1B2 and HARS

Number of citations of the paper that reports this interaction (PMID 11829477)
11

Data Source:
BioGRID (affinity chromatography technology, pull down)
HPRD (in vivo, in vitro)

		EEF1B2	HARS
Gene Name		eukaryotic translation elongation factor 1 beta 2	histidyl-tRNA synthetase
Image
Gene Ontology Annotations	Cellular Component	Cytosol Eukaryotic Translation Elongation Factor 1 Complex	Cytoplasm Cytosol
	Molecular Function	Translation Elongation Factor Activity Protein Binding	Histidine-tRNA Ligase Activity ATP Binding
	Biological Process	Translation Translational Elongation Gene Expression Cellular Protein Metabolic Process	Translation TRNA Aminoacylation For Protein Translation Histidyl-tRNA Aminoacylation Gene Expression
Pathways		Translation Eukaryotic Translation Elongation	Cytosolic tRNA aminoacylation tRNA Aminoacylation
Drugs			L-Histidine
Diseases
GWAS
Protein-Protein Interactions		10 interactors: AARS APP CSNK2A1 CSNK2A2 DRD3 EEF1G HARS TIMP1 ULK2 VHL	6 interactors: EEF1B2 EEF1G EIF3I RPL5 TARS TNIK
Entrez ID		1933	3035
HPRD ID		02804	00827
Ensembl ID		ENSG00000114942	ENSG00000170445
Uniprot IDs		P24534	B3KWE1 B4DDD8 B4E1C5 P12081
PDB IDs		1B64	1X59 2LW7 4G84 4G85
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Proteolysis Negative Regulation Of Protein Processing Negative Regulation Of Protein Catabolic Process Regulation Of Protein Processing Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Cell Cycle Neuromuscular Process Response To External Stimulus Regulation Of Cell Cycle Process Cell Morphogenesis Cellular Protein Metabolic Process Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Negative Regulation Of Cellular Metabolic Process Regulation Of Growth Regulation Of Mitotic Cell Cycle Phase Transition Neuron Projection Morphogenesis Regulation Of Cell Cycle Phase Transition Regulation Of Proteolysis Nervous System Development Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Regulation Of Cell Division Negative Regulation Of Endopeptidase Activity Cell Morphogenesis Involved In Differentiation Negative Regulation Of Peptidase Activity Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Spindle Checkpoint Negative Regulation Of Neurogenesis Regulation Of Developmental Growth Negative Regulation Of Catalytic Activity Regulation Of Mitotic Metaphase/anaphase Transition Generation Of Neurons Developmental Process Negative Regulation Of Cellular Protein Metabolic Process Protein Metabolic Process Neuron Projection Development Cell Projection Morphogenesis Negative Regulation Of Cell Development Visual Learning Cell Part Morphogenesis Neurogenesis Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Protein Metabolic Process Visual Behavior Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Apoptotic Process Platelet Degranulation	Translation Translational Elongation Cellular Protein Metabolic Process Protein Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Threonyl-tRNA Aminoacylation Translational Initiation Biosynthetic Process Activation Of JNKK Activity Ribonucleoprotein Complex Biogenesis Protein Localization To Membrane Microvillus Assembly Microvillus Organization
Tagcloud ?		aberration aberrations amplicons amplifications cna cnas concordance concordant copy featured gains gistic grouped hnf4a instable microsatellite msi mss oncogenes petacc ptk6 q q23 reinforce smad4 suppressors unlinked wnk1 wwox	ascertain botulinum cgi clinician compulsive dysphonia ghq hamilton hdrs impression obsessive pathologist psychometrics psychoticism ql rated rating reevaluated sds somatization somatoform spasmodic speech subscales toxin unilaterally vocal voice zung
Tagcloud (Difference) ?		aberration aberrations amplicons amplifications cna cnas concordance concordant copy featured gains gistic grouped hnf4a instable microsatellite msi mss oncogenes petacc ptk6 q q23 reinforce smad4 suppressors unlinked wnk1 wwox	ascertain botulinum cgi clinician compulsive dysphonia ghq hamilton hdrs impression obsessive pathologist psychometrics psychoticism ql rated rating reevaluated sds somatization somatoform spasmodic speech subscales toxin unilaterally vocal voice zung
Tagcloud (Intersection) ?