TMEM80 and LSMEM1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMEM80	LSMEM1
Description		transmembrane protein 80	leucine rich single-pass membrane protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cilium Membrane Ciliary Transition Zone Cell Projection	Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Non-motile Cilium Assembly
Pathways
Drugs
Diseases
GWAS			Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
Interacting Genes		65 interacting genes: ADGRE2 AGTR1 AIG1 AQP1 ARL6IP6 BET1 BIK C11orf24 C14orf180 C3orf52 C5orf46 CCDC167 CD63 CLDN11 CLDN19 CLDN8 CLDND2 CLEC2D CMTM5 CNIH3 COL4A5 CXCR2 CYBC1 DOLK EMD ERMP1 FAM20B FAM3C FKBP8 FXYD3 GPR37L1 IER3IP1 LAT LSMEM1 MALL MRAP2 NKG7 PRB1 PTPN9 PTPRN RPRM SERP2 SLC30A8 SLC66A2 SMAGP SMCO4 STATH STX7 SYNGR1 TLCD1 TMEM100 TMEM107 TMEM109 TMEM120B TMEM128 TMEM14A TMEM243 TMEM65 TNFRSF10C TRARG1 TSPAN1 TSPO2 TVP23B VKORC1L1 WNT4	6 interacting genes: APP CD53 LSMEM2 MAL TMEM80 ZDHHC15
Entrez ID		283232	286006
HPRD ID		14143	08258
Ensembl ID		ENSG00000177042	ENSG00000181016
Uniprot IDs		A0A0A0MTU4 A0AAA9X375 E9PQJ9 Q96HE8	Q8N8F7
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Plasma Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Protein Binding	Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Central Nervous System Development Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Positive Regulation Of Apoptotic Signaling Pathway Growth Cone Filopodium Regulation Of Postsynapse Organization Cellular Localization Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Localization Within Membrane Protein Insertion Into Plasma Membrane Membrane Raft Polarization Hinge Region Between Urothelial Plaques Of Apical Plasma Membrane Protein Targeting To Golgi Apparatus Regulation Of Extrinsic Apoptotic Signaling Pathway Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Protein Localization To Paranode Region Of Axon Peptidase Activator Activity Involved In Apoptotic Process Protein-cysteine S-myristoyltransferase Activity Regulation Of Spontaneous Synaptic Transmission Developmental Maturation NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Establishment Of Protein Localization To Membrane Protein-cysteine S-stearoyltransferase Activity Membrane Raft Axon Choice Point Recognition
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