PPM1F and CAMK2G

Number of citations of the paper that reports this interaction (PMID 11559703)
13

Data Source:
BioGRID (enzymatic study)

		PPM1F	CAMK2G
Gene Name		protein phosphatase, Mg2+/Mn2+ dependent, 1F	calcium/calmodulin-dependent protein kinase II gamma
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Protein Complex Perinuclear Region Of Cytoplasm	Nucleoplasm Cytosol Plasma Membrane Membrane Endocytic Vesicle Membrane Sarcoplasmic Reticulum Membrane
	Molecular Function	Protein Serine/threonine Phosphatase Activity Protein Binding Phosphatase Activity Calmodulin-dependent Protein Phosphatase Activity Metal Ion Binding	Calmodulin-dependent Protein Kinase Activity Calcium-dependent Protein Serine/threonine Phosphatase Activity Protein Binding Calmodulin Binding ATP Binding Protein Homodimerization Activity
	Biological Process	Negative Regulation Of Protein Kinase Activity Positive Regulation Of Gene Expression Positive Regulation Of Epithelial Cell Migration Positive Regulation Of Cell-substrate Adhesion Histone Dephosphorylation Negative Regulation Of Peptidyl-serine Phosphorylation Cellular Response To Drug Peptidyl-threonine Dephosphorylation Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Protein Kinase Activity By Regulation Of Protein Phosphorylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Growth Positive Regulation Of Chemotaxis Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Focal Adhesion Assembly Intrinsic Apoptotic Signaling Pathway	G1/S Transition Of Mitotic Cell Cycle Calcium Ion Transport Synaptic Transmission Nervous System Development Regulation Of Skeletal Muscle Adaptation Dephosphorylation Cytokine-mediated Signaling Pathway Insulin Secretion Cell Differentiation Cellular Response To Heat Protein Autophosphorylation Protein Oligomerization Regulation Of Calcium Ion Transport Interferon-gamma-mediated Signaling Pathway Regulation Of Cellular Response To Heat Regulation Of Relaxation Of Cardiac Muscle
Pathways			Interferon Signaling Cytokine Signaling in Immune system Cellular response to heat stress CREB phosphorylation through the activation of Ras Trafficking of AMPA receptors Interferon gamma signaling HSF1-dependent transactivation Activation of NMDA receptor upon glutamate binding and postsynaptic events CREB phosphorylation through the activation of CaMKII Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity Unblocking of NMDA receptor, glutamate binding and activation Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Ras activation uopn Ca2+ infux through NMDA receptor Post NMDA receptor activation events Transmission across Chemical Synapses
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder ( 18839057)
Protein-Protein Interactions		8 interactors: ARHGEF7 CAMK2A CAMK2G FAM161A FEM1A FEM1B MARS PAK1	31 interactors: ACTN2 ACTN4 ADCY3 ATF1 CABP2 CALM1 CHAT CREM EGFR FLNA GRIA1 GRIA4 GRIN1 GRIN2B LRRC7 MYLK PEA15 PLCB3 PPM1F RCHY1 RRAD RYR1 SMAD2 SMAD3 SMAD4 SPR STAT1 STMN1 SYN1 TH TIAM1
Entrez ID		9647	818
HPRD ID		10163	03672
Ensembl ID		ENSG00000100034	ENSG00000148660
Uniprot IDs		B7Z2C3 P49593	Q13280 Q13555 Q5SWX3
PDB IDs			2UX0 2V7O
Enriched GO Terms of Interacting Partners?		Protein Autophosphorylation Regulation Of Cellular Response To Heat Apoptotic Process Programmed Cell Death Cellular Response To Heat Cell Death Death Regulation Of Ubiquitin-protein Transferase Activity Ephrin Receptor Signaling Pathway Response To Heat Methionyl-tRNA Aminoacylation Cellular Protein Metabolic Process Interferon-gamma-mediated Signaling Pathway Positive Regulation Of Lamellipodium Morphogenesis Cellular Response To Interferon-gamma G1/S Transition Of Mitotic Cell Cycle Response To Interferon-gamma Negative Regulation Of Cell Proliferation Involved In Contact Inhibition Epithelial Cell Maturation Involved In Prostate Gland Development Response To Temperature Stimulus Regulation Of Calcium Ion Transport Cellular Protein Modification Process Innate Immune Response Regulation Of Protein Ubiquitination Cellular Response To Organic Substance Cell Projection Morphogenesis Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Regulation Of Lamellipodium Morphogenesis Regulation Of Relaxation Of Cardiac Muscle Histone H3-T11 Phosphorylation Cell Part Morphogenesis Morphogenesis Of A Branching Epithelium Regulation Of Relaxation Of Muscle Protein Metabolic Process Morphogenesis Of A Branching Structure Regulation Of Skeletal Muscle Adaptation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Immune System Process Contact Inhibition Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Fibroblast Migration Cell Projection Assembly Regulation Of DNA Damage Checkpoint Cell Morphogenesis Response To Abiotic Stimulus Calcium Ion Transport Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Regulation Of Catalytic Activity Cell Projection Organization	Signaling Cell Communication Synaptic Transmission Cellular Response To Stimulus Cell-cell Signaling Response To Organic Cyclic Compound Enzyme Linked Receptor Protein Signaling Pathway Response To Stimulus Cellular Response To Growth Factor Stimulus Neuron-neuron Synaptic Transmission Signal Transduction Response To Growth Factor Response To Abiotic Stimulus Response To Organic Substance SMAD Protein Complex Assembly Cell Development Intracellular Signal Transduction Ionotropic Glutamate Receptor Signaling Pathway Synaptic Transmission, Glutamatergic Regulation Of Cellular Process Response To Organonitrogen Compound Cell Differentiation Cell Projection Organization Regulation Of Signaling Glutamate Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway System Development Multicellular Organismal Development Neuron Development Regulation Of Synaptic Transmission Platelet Degranulation Cell Morphogenesis Involved In Differentiation Positive Regulation Of Transport Secretion By Cell Anatomical Structure Morphogenesis Positive Regulation Of Cellular Component Movement Response To Stress Mesenchyme Development Organ Development Positive Regulation Of Epithelial To Mesenchymal Transition Positive Regulation Of Protein Import Into Nucleus Neuron Differentiation Cell Morphogenesis Involved In Neuron Differentiation Neurotrophin TRK Receptor Signaling Pathway Cell Surface Receptor Signaling Pathway Cellular Response To Organic Substance Neurotrophin Signaling Pathway Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of Nucleocytoplasmic Transport Response To Amphetamine
Tagcloud ?			agouti cd47 chances clstn2 consonant enpp1 epha5a gad2 gria3 grin2b kif minipumps myo5a negr1 neuroplasticity ntrk2 ntrk3 ppp3r1 prdx1 predecessors serotonine slc2a4 sv2b syn2 synaptogenesis synj2 therapeutical venlafaxine vlx
Tagcloud (Difference) ?			agouti cd47 chances clstn2 consonant enpp1 epha5a gad2 gria3 grin2b kif minipumps myo5a negr1 neuroplasticity ntrk2 ntrk3 ppp3r1 prdx1 predecessors serotonine slc2a4 sv2b syn2 synaptogenesis synj2 therapeutical venlafaxine vlx
Tagcloud (Intersection) ?