CD40LG and CD5L

Number of citations of the paper that reports this interaction (PMID 11981870)
6

Data Source:
HPRD (in vivo)

		CD40LG	CD5L
Gene Name		CD40 ligand	CD5 molecule-like
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane	Extracellular Region Extracellular Space Membrane Extracellular Vesicular Exosome Blood Microparticle
	Molecular Function	Cytokine Activity Tumor Necrosis Factor Receptor Binding CD40 Receptor Binding	Scavenger Receptor Activity
	Biological Process	Inflammatory Response Leukocyte Cell-cell Adhesion Platelet Activation B Cell Differentiation Positive Regulation Of Interleukin-12 Production B Cell Proliferation Negative Regulation Of Apoptotic Process Isotype Switching Immunoglobulin Secretion Regulation Of Immune Response Regulation Of Immunoglobulin Secretion Positive Regulation Of Endothelial Cell Apoptotic Process	Receptor-mediated Endocytosis Apoptotic Process Cellular Defense Response
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: CD40 CD5L IGHG1 IGKC RNF128 TP53	1 interactors: CD40LG
Entrez ID		959	922
HPRD ID		02311	03997
Ensembl ID		ENSG00000102245	ENSG00000073754
Uniprot IDs		P29965 Q3L8U2	O43866
PDB IDs		1ALY 1I9R 3LKJ 3QD6
Enriched GO Terms of Interacting Partners?		Immune Response-regulating Cell Surface Receptor Signaling Pathway Defense Response Immune Response-regulating Signaling Pathway Lymphocyte Proliferation Mononuclear Cell Proliferation Response To Stress Positive Regulation Of Immune Response Leukocyte Proliferation Endocytosis Complement Activation, Classical Pathway Humoral Immune Response Mediated By Circulating Immunoglobulin Negative Regulation Of Macromitophagy Oligodendrocyte Apoptotic Process Complement Activation Positive Regulation Of Peptidyl-tyrosine Phosphorylation B Cell Activation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Negative Regulation Of Helicase Activity Protein Activation Cascade Immunoglobulin Mediated Immune Response B Cell Mediated Immunity Immune System Process Regulation Of Immune Response Positive Regulation Of Immune System Process Regulation Of Peptidyl-tyrosine Phosphorylation Humoral Immune Response Positive Regulation Of Cell Aging Positive Regulation Of Thymocyte Apoptotic Process Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Positive Regulation Of Isotype Switching To IgG Isotypes Mitochondrial DNA Repair Phagocytosis Leukocyte Mediated Immunity Regulation Of Mitochondrion Degradation T Cell Proliferation Involved In Immune Response B Cell Lineage Commitment Glial Cell Apoptotic Process Fc Receptor Signaling Pathway Adaptive Immune Response Immune Response-activating Cell Surface Receptor Signaling Pathway Positive Regulation Of Tyrosine Phosphorylation Of Stat1 Protein Oxidative Stress-induced Premature Senescence Regulation Of Isotype Switching To IgG Isotypes Positive Regulation Of Protein Kinase C Signaling ER Overload Response Negative Regulation Of Macroautophagy Positive Regulation Of Endothelial Cell Apoptotic Process Stress-induced Premature Senescence	Immunoglobulin Secretion Positive Regulation Of Endothelial Cell Apoptotic Process Regulation Of Immunoglobulin Secretion Isotype Switching Regulation Of Endothelial Cell Apoptotic Process Somatic Recombination Of Immunoglobulin Gene Segments Somatic Diversification Of Immunoglobulins B Cell Proliferation Immunoglobulin Production Involved In Immunoglobulin Mediated Immune Response Positive Regulation Of Interleukin-12 Production B Cell Activation Involved In Immune Response Immunoglobulin Production Regulation Of Interleukin-12 Production B Cell Differentiation Lymphocyte Proliferation Mononuclear Cell Proliferation Protein Secretion Leukocyte Proliferation Leukocyte Activation Involved In Immune Response B Cell Activation Immunoglobulin Mediated Immune Response B Cell Mediated Immunity Platelet Activation DNA Recombination Lymphocyte Differentiation Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Leukocyte Mediated Immunity Adaptive Immune Response Leukocyte Cell-cell Adhesion Leukocyte Differentiation Positive Regulation Of Cytokine Production Regulation Of Protein Secretion Lymphocyte Activation Blood Coagulation Inflammatory Response Hemostasis Leukocyte Activation
Tagcloud ?		admixed ancestry aspirin cigarette comparisons contributing contributor hispanic lifestyle mediators menopausal na nhw padj partp regular rs4149578 rs5030728 rs7696175 steroidal tlr tlr1 tlr3 tlr4 tnfrsf1a tnfsf1a toll tra2 traf2	a1at abnormal afford antitrypsin biomarker cascade chains childhood clusterin correcting deposition differential displays electrophoresis elucidate febrile fibrin fibrinogen immunoglobulin immunosorbent involve kawasaki kd polyacrylamide profiling proteomic sought subjected
Tagcloud (Difference) ?		admixed ancestry aspirin cigarette comparisons contributing contributor hispanic lifestyle mediators menopausal na nhw padj partp regular rs4149578 rs5030728 rs7696175 steroidal tlr tlr1 tlr3 tlr4 tnfrsf1a tnfsf1a toll tra2 traf2	a1at abnormal afford antitrypsin biomarker cascade chains childhood clusterin correcting deposition differential displays electrophoresis elucidate febrile fibrin fibrinogen immunoglobulin immunosorbent involve kawasaki kd polyacrylamide profiling proteomic sought subjected
Tagcloud (Intersection) ?