CCL4L2 and SLC7A1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CCL4L2	SLC7A1
Description		C-C motif chemokine ligand 4 like 2	solute carrier family 7 member 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Plasma Membrane Basal Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Protein-containing Complex
	Molecular Function		L-ornithine Transmembrane Transporter Activity Virus Receptor Activity L-histidine Transmembrane Transporter Activity Protein Binding Amino Acid Transmembrane Transporter Activity Basic Amino Acid Transmembrane Transporter Activity L-lysine Transmembrane Transporter Activity Transmembrane Transporter Activity L-arginine Transmembrane Transporter Activity
	Biological Process		Amino Acid Transport L-amino Acid Transport Lysine Transport Ornithine Transport Positive Regulation Of T Cell Proliferation Symbiont Entry Into Host Cell Transmembrane Transport Amino Acid Import Across Plasma Membrane L-arginine Import Across Plasma Membrane Transport Across Blood-brain Barrier L-ornithine Transmembrane Transport L-lysine Transmembrane Transport L-histidine Import Across Plasma Membrane L-arginine Transmembrane Transport
Pathways		G alpha (i) signalling events	Amino acid transport across the plasma membrane
Drugs			Lysine Arginine Ornithine
Diseases
GWAS		Body mass index ( 26426971) Protein quantitative trait loci ( 18464913)	Appendicular lean mass ( 33097823) Blood osmolality (transformed sodium) ( 28360221) Diastolic blood pressure ( 27841878) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (diuretics) ( 31015401) Metabolite levels ( 23823483) Systolic blood pressure ( 27841878 30578418)
Interacting Genes		33 interacting genes: AQP6 ARL13B CATSPER4 CERS4 CLRN1 COMT COQ9 CPLX4 CREB3L1 EBP ELOVL4 ERVFRD-1 FAM209A GET1 GPR152 GPR42 ITM2C JAGN1 MRM1 REEP4 RETREG3 SGPL1 SLC10A2 SLC18A1 SLC30A2 SLC61A1 SLC71A2 SLC7A1 SLC7A14 SSMEM1 TMEM179B TMEM51 VSIR	56 interacting genes: ADGRB3 APOA2 APP AQP6 ATP6V0C C8A CBLIF CCL4 CCL4L2 CD40 CD79A CDIPT CERS4 CMTM2 CREB3L1 EMC6 FAM241B FATE1 FCER1G GALNT15 GET1 GLB1 GPR152 HERPUD2 LEPROT LEPROTL1 LMNA MFF MGST3 MS4A13 NUCB2 ORMDL3 PDCD1LG2 PNLIPRP1 PSCA PTPN9 RNF144A SACM1L SCN3B SEC23A SLC10A6 SLC18A2 SLC30A2 SLC39A2 SLC39A9 SLC52A1 SMCO4 ST6GAL2 STIM1 TMBIM6 TMEM14A TMEM19 TMEM237 TRARG1 TSPO2 YIPF4
Entrez ID		9560	6541
HPRD ID		16030	00091
Ensembl ID		ENSG00000276070	ENSG00000139514
Uniprot IDs		Q8NHW4	P30825
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Norepinephrine Transport	Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Intracellular Monoatomic Cation Homeostasis Intracellular Chemical Homeostasis Intracellular Monoatomic Ion Homeostasis Serotonin Secretion Zinc Ion Transmembrane Transporter Activity Chemical Homeostasis Zinc Ion Transport Zinc Ion Transmembrane Transport Plasma Membrane Monoatomic Cation Homeostasis Monoatomic Ion Transport Inorganic Cation Transmembrane Transport Monoatomic Cation Transport Organic Hydroxy Compound Transport Monoatomic Ion Homeostasis Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Cellular Homeostasis Transmembrane Transport Inorganic Ion Transmembrane Transport Negative Regulation Of Growth Hormone Receptor Signaling Pathway Inorganic Ion Homeostasis Monoatomic Ion Transmembrane Transport Serotonin Transport Metal Ion Transport Regulation Of Growth Hormone Receptor Signaling Pathway Acetylcholine Receptor Binding Monoatomic Cation Transmembrane Transport Neuron Remodeling
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