SLC7A1 and SLC52A1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC7A1	SLC52A1
Description		solute carrier family 7 member 1	solute carrier family 52 member 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Basal Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Protein-containing Complex	Plasma Membrane Membrane
	Molecular Function	L-ornithine Transmembrane Transporter Activity Virus Receptor Activity L-histidine Transmembrane Transporter Activity Protein Binding Amino Acid Transmembrane Transporter Activity Basic Amino Acid Transmembrane Transporter Activity L-lysine Transmembrane Transporter Activity Transmembrane Transporter Activity L-arginine Transmembrane Transporter Activity	Virus Receptor Activity Protein Binding Riboflavin Transmembrane Transporter Activity
	Biological Process	Amino Acid Transport L-amino Acid Transport Lysine Transport Ornithine Transport Positive Regulation Of T Cell Proliferation Symbiont Entry Into Host Cell Transmembrane Transport Amino Acid Import Across Plasma Membrane L-arginine Import Across Plasma Membrane Transport Across Blood-brain Barrier L-ornithine Transmembrane Transport L-lysine Transmembrane Transport L-histidine Import Across Plasma Membrane L-arginine Transmembrane Transport	Riboflavin Metabolic Process Riboflavin Transport Symbiont Entry Into Host Cell
Pathways		Amino acid transport across the plasma membrane	Vitamin B2 (riboflavin) metabolism
Drugs		Lysine Arginine Ornithine
Diseases
GWAS		Appendicular lean mass ( 33097823) Blood osmolality (transformed sodium) ( 28360221) Diastolic blood pressure ( 27841878) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (diuretics) ( 31015401) Metabolite levels ( 23823483) Systolic blood pressure ( 27841878 30578418)	Age at first sexual intercourse ( 34211149) Keratoconus ( 33649486) Lung adenocarcinoma ( 28604730)
Interacting Genes		56 interacting genes: ADGRB3 APOA2 APP AQP6 ATP6V0C C8A CBLIF CCL4 CCL4L2 CD40 CD79A CDIPT CERS4 CMTM2 CREB3L1 EMC6 FAM241B FATE1 FCER1G GALNT15 GET1 GLB1 GPR152 HERPUD2 LEPROT LEPROTL1 LMNA MFF MGST3 MS4A13 NUCB2 ORMDL3 PDCD1LG2 PNLIPRP1 PSCA PTPN9 RNF144A SACM1L SCN3B SEC23A SLC10A6 SLC18A2 SLC30A2 SLC39A2 SLC39A9 SLC52A1 SMCO4 ST6GAL2 STIM1 TMBIM6 TMEM14A TMEM19 TMEM237 TRARG1 TSPO2 YIPF4	9 interacting genes: AQP6 CREB3L1 GJA8 IFNGR2 SGCB SHISAL1 SLC7A1 TMEM179B TMEM237
Entrez ID		6541	55065
HPRD ID		00091	07432
Ensembl ID		ENSG00000139514	ENSG00000132517
Uniprot IDs		P30825	Q9NWF4
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Intracellular Monoatomic Cation Homeostasis Intracellular Chemical Homeostasis Intracellular Monoatomic Ion Homeostasis Serotonin Secretion Zinc Ion Transmembrane Transporter Activity Chemical Homeostasis Zinc Ion Transport Zinc Ion Transmembrane Transport Plasma Membrane Monoatomic Cation Homeostasis Monoatomic Ion Transport Inorganic Cation Transmembrane Transport Monoatomic Cation Transport Organic Hydroxy Compound Transport Monoatomic Ion Homeostasis Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Cellular Homeostasis Transmembrane Transport Inorganic Ion Transmembrane Transport Negative Regulation Of Growth Hormone Receptor Signaling Pathway Inorganic Ion Homeostasis Monoatomic Ion Transmembrane Transport Serotonin Transport Metal Ion Transport Regulation Of Growth Hormone Receptor Signaling Pathway Acetylcholine Receptor Binding Monoatomic Cation Transmembrane Transport Neuron Remodeling	PH-gated Chloride Channel Activity Nitrate Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transporter Activity Nitrate Transmembrane Transport Transmembrane Transport Membrane Carbon Dioxide Transmembrane Transport Gap Junction-mediated Intercellular Transport Type II Interferon Receptor Activity Sarcoglycan Complex Dystroglycan Complex Glucose Import In Response To Insulin Stimulus L-lysine Transmembrane Transport Ornithine Transport L-lysine Transmembrane Transporter Activity L-histidine Transmembrane Transporter Activity Lysine Transport L-ornithine Transmembrane Transport L-histidine Transmembrane Transport L-ornithine Transmembrane Transporter Activity L-arginine Import Across Plasma Membrane L-histidine Import Across Plasma Membrane Extracellular Matrix Constituent Secretion Cytoplasmic Vesicle Membrane Cone Photoreceptor Outer Segment Monoatomic Anion Channel Activity Ammonium Transmembrane Transport Ammonium Channel Activity Renal Water Transport Intercellular Transport Positive Regulation Of Glutamate Receptor Signaling Pathway Type III Interferon-mediated Signaling Pathway Basic Amino Acid Transmembrane Transporter Activity Aromatic Amino Acid Transport L-arginine Transmembrane Transporter Activity Rod Photoreceptor Outer Segment
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