TMEM106A and TNMD

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMEM106A	TNMD
Description		transmembrane protein 106A	tenomodulin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Nucleus Nuclear Envelope Cytoplasm Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Immune System Process Glycoprotein Biosynthetic Process Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Interleukin-6 Production Positive Regulation Of Tumor Necrosis Factor Production Macrophage Activation Positive Regulation Of Canonical NF-kappaB Signal Transduction Positive Regulation Of MAPK Cascade Innate Immune Response Positive Regulation Of MHC Class II Biosynthetic Process Positive Regulation Of Nitric Oxide Metabolic Process	Endothelial Cell Morphogenesis Negative Regulation Of Endothelial Cell Proliferation Negative Regulation Of Angiogenesis
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 30072576)
Interacting Genes		12 interacting genes: ARF1 ENTPD3 ERG28 GJB2 GOSR2 IGFBP5 RHOU TMEM107 TMEM128 TMEM86B TNMD TSPAN4	17 interacting genes: AMIGO1 ARL13B BCL2L13 BNIP3 BNIP3L CD33 CREB3L1 FAM209A FCGR1A GGT6 HHLA2 KIR3DL3 LMNA MYG1 SPAG4 TMEM106A TMEM79
Entrez ID		113277	64102
HPRD ID		11315	02352
Ensembl ID		ENSG00000184988	ENSG00000000005
Uniprot IDs		B7Z779 Q96A25	Q9H2S6
PDB IDs
Enriched GO Terms of Interacting Partners?			Mitochondrial Protein Catabolic Process Negative Regulation Of Membrane Potential Nuclear Envelope Negative Regulation Of Mitochondrial Membrane Potential Mitochondrial Outer Membrane Permeabilization Membrane Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Mitochondrial Envelope Mitochondrial Outer Membrane Permeabilization Involved In Programmed Cell Death Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Positive Regulation Of Mitochondrial Membrane Permeability Positive Regulation Of Membrane Permeability Cellular Response To Oxygen Levels Fc-gamma Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Regulation Of Tumor Necrosis Factor Production Regulation Of Release Of Cytochrome C From Mitochondria Mitochondrion Autophagosome Adaptor Activity High-affinity IgG Receptor Activity Nuclear Inner Membrane Regulation Of Autophagy Of Mitochondrion Mitophagy Regulation Of Mitochondrial Membrane Permeability Fc Receptor Signaling Pathway
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