TMEM106A and TMEM107

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMEM106A	TMEM107
Description		transmembrane protein 106A	transmembrane protein 107
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Cilium Membrane Ciliary Transition Zone MKS Complex Cell Projection
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Immune System Process Glycoprotein Biosynthetic Process Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Interleukin-6 Production Positive Regulation Of Tumor Necrosis Factor Production Macrophage Activation Positive Regulation Of Canonical NF-kappaB Signal Transduction Positive Regulation Of MAPK Cascade Innate Immune Response Positive Regulation Of MHC Class II Biosynthetic Process Positive Regulation Of Nitric Oxide Metabolic Process	Detection Of Nodal Flow Determination Of Left/right Symmetry Regulation Of Gene Expression Neural Tube Patterning Cell Projection Organization Embryonic Digit Morphogenesis Cilium Organization Roof Of Mouth Development Cilium Assembly Craniofacial Suture Morphogenesis Protein Localization To Ciliary Transition Zone Non-motile Cilium Assembly
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 30072576)	Diastolic blood pressure ( 30224653) Urinary potassium excretion ( 31409800)
Interacting Genes		12 interacting genes: ARF1 ENTPD3 ERG28 GJB2 GOSR2 IGFBP5 RHOU TMEM107 TMEM128 TMEM86B TNMD TSPAN4	45 interacting genes: AQP3 AQP6 BIK CCL21 CD40 CD79A CLN8 CLSTN3 CPLX4 EBAG9 ERGIC3 EVI2B FAM209A FAM210B FCER1G GJA5 GJA8 GPX8 KCNA5 KCNJ6 LHFPL5 LMNA MGST3 MS4A3 PDZK1IP1 PGRMC2 PIGP SAR1A SLC10A6 SLC30A2 SLC35H1 SLC39A2 SYT2 THAP4 TMEM106A TMEM139 TMEM167B TMEM234 TMEM237 TMEM31 TMEM51 TMEM52B TMEM80 TMEM86B VMA21
Entrez ID		113277	84314
HPRD ID		11315	14400
Ensembl ID		ENSG00000184988	ENSG00000179029
Uniprot IDs		B7Z779 Q96A25	E9PIH0 Q6UX40
PDB IDs
Enriched GO Terms of Interacting Partners?			Membrane Transmembrane Transport Protein Binding Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Monoatomic Ion Transport Metal Ion Transport Renal Water Transport
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