IGDCC3 and FTL

Number of citations of the paper that reports this interaction (PubMedID 11591653)
29

Data Source:
HPRD (in vivo)

		IGDCC3	FTL
Description		immunoglobulin superfamily DCC subclass member 3	ferritin light chain
Image		No pdb structure
GO Annotations	Cellular Component	Membrane	Extracellular Region Cytoplasm Lysosome Autophagosome Cytosol Membrane Cytoplasmic Vesicle Azurophil Granule Lumen Autolysosome Extracellular Exosome Ferritin Complex
	Molecular Function		Iron Ion Binding Protein Binding Ferrous Iron Binding Ferric Iron Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Neuromuscular Process Controlling Balance Cell-cell Adhesion	Iron Ion Transport Intracellular Iron Ion Homeostasis
Pathways			Scavenging by Class A Receptors Golgi Associated Vesicle Biogenesis Neutrophil degranulation Iron uptake and transport
Drugs			Iron Dextran Protoporphyrin Ferric pyrophosphate Sodium ferric gluconate complex Ferric pyrophosphate citrate
Diseases			Neurodegeneration with brain iron accumulation (NBIA); Hallervorden-Spatz syndrome; Neuroferritinopathy; Aceruloplasminemia
GWAS
Interacting Genes		1 interacting genes: FTL	31 interacting genes: ACO1 CLEC4G FTH1 GADD45A GLP1R GRB2 HTT IGDCC3 KNG1 KPNA3 MAP3K12 MEOX2 MPHOSPH6 MTNR1B MYOC MYOG NTAQ1 PALS2 PIK3CA PPP1CC PTN RAP2A SDCBP SLC13A1 SMAD9 SPINK7 TAF10 UBC USHBP1 VKORC1 ZDHHC17
Entrez ID		9543	2512
HPRD ID		09169	00616
Ensembl ID		ENSG00000174498	ENSG00000087086
Uniprot IDs		Q8IVU1	A0A384MDR3 P02792
PDB IDs			2FFX 2FG4 2FG8 3KXU 4V6B 5LG8 6TR9 6TS0 6TS1 6TSA 6TSF 6TSJ 6WX6
Enriched GO Terms of Interacting Partners?		Pigment Granule Localization Establishment Of Melanosome Localization Regulation Of Response To Food Microtubule Anchoring At Centrosome Pericentriolar Material Sperm Flagellum Assembly Regulation Of Cilium Beat Frequency Protein Localization To Non-motile Cilium BBSome Maintenance Of Protein Location In Nucleus Photoreceptor Cell Outer Segment Organization Retinal Rod Cell Development Negative Regulation Of Appetite Melanosome Localization Response To Leptin Protein Localization To Photoreceptor Outer Segment Brain Morphogenesis Microtubule Anchoring Striatum Development Fat Pad Development Erythrocyte Homeostasis Melanosome Transport Leptin-mediated Signaling Pathway Ventricular System Development Face Development Sensory Processing Pigment Granule Transport Dynactin Binding Regulation Of Non-motile Cilium Assembly Retina Homeostasis Protein Localization To Centrosome Negative Regulation Of Appetite By Leptin-mediated Signaling Pathway Microtubule Anchoring At Microtubule Organizing Center Regulation Of Appetite Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Negative Regulation Of Systemic Arterial Blood Pressure Ferritin Complex Ferrous Iron Binding Autolysosome Ferric Iron Binding B Cell Homeostasis Non-motile Cilium Myeloid Cell Homeostasis Regulation Of Response To Nutrient Levels Ciliary Transition Zone Positive Regulation Of Multicellular Organism Growth Positive Regulation Of Cilium Assembly Eye Photoreceptor Cell Development Regulation Of Cilium Movement Photoreceptor Cell Development
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