STX8 and NAPA

Number of citations of the paper that reports this interaction (PMID 10683148)
10

Data Source:
HPRD (in vivo)

		STX8	NAPA
Gene Name		syntaxin 8	N-ethylmaleimide-sensitive factor attachment protein, alpha
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Lysosomal Membrane Endosome Early Endosome Late Endosome Endoplasmic Reticulum Trans-Golgi Network Integral Component Of Plasma Membrane SNARE Complex Late Endosome Membrane Vesicle Perinuclear Region Of Cytoplasm Recycling Endosome	Vacuolar Membrane Cytosol Membrane SNARE Complex Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Extracellular Vesicular Exosome
	Molecular Function	SNAP Receptor Activity Chloride Channel Inhibitor Activity Syntaxin Binding Ubiquitin Protein Ligase Binding	Soluble NSF Attachment Protein Activity Protein Binding Syntaxin Binding
	Biological Process	Transport Intracellular Protein Transport Vesicle Fusion Endosome To Lysosome Transport Early Endosome To Late Endosome Transport Regulation Of Protein Localization To Plasma Membrane	Intracellular Protein Transport Intra-Golgi Vesicle-mediated Transport Post-Golgi Vesicle-mediated Transport Brain Development Regulation Of Synaptic Vesicle Priming Neuron Differentiation Synaptic Transmission, Glutamatergic SNARE Complex Disassembly Apical Protein Localization Membrane Organization Membrane Fusion
Pathways			Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS
Protein-Protein Interactions		17 interactors: ACVR1 CALM1 CLN8 COPA CREB3 NAPA NAPG NSF STX1A STX4 STX7 TGFBR1 UBC VPS11 VPS18 VTI1B WDR91	17 interactors: APP BNIP1 GNA12 GOSR1 GOSR2 NSF RTN4 SNAP23 SNAP25 STX12 STX1A STX4 STX5 STX7 STX8 TRPC3 VAMP8
Entrez ID		9482	8775
HPRD ID		05012	04447
Ensembl ID			ENSG00000105402
Uniprot IDs		Q9UNK0	P54920
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Organization Membrane Fusion Vesicle Docking Membrane Docking Intracellular Protein Transport Cellular Localization Cellular Protein Localization Vesicle-mediated Transport Establishment Of Localization In Cell Intracellular Transport Protein Localization Protein Transport Establishment Of Protein Localization Regulation Of Cellular Localization Golgi Vesicle Transport Vesicle Fusion Intra-Golgi Vesicle-mediated Transport Exocytosis Secretion Organelle Fusion Vesicle Organization Post-Golgi Vesicle-mediated Transport Transport Secretion By Cell Regulation Of Exocytosis Regulation Of Vesicle-mediated Transport Regulation Of Synaptic Vesicle Priming Regulation Of Protein Localization To Plasma Membrane Regulation Of Protein Localization Vesicle Docking Involved In Exocytosis Regulation Of Cellular Component Organization Synaptic Vesicle Fusion To Presynaptic Membrane Synaptic Transmission Pathway-restricted SMAD Protein Phosphorylation Regulation Of Signaling Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Pharyngeal System Development Positive Regulation Of Transport Energy Reserve Metabolic Process Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Neurotransmitter Levels Organelle Localization Activin Receptor Signaling Pathway Neurotransmitter Transport Regulation Of Synaptic Vesicle Exocytosis Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Apoptotic Process Cell-cell Signaling Negative Regulation Of Apoptotic Process Response To Transforming Growth Factor Beta	Membrane Fusion Organelle Fusion Vesicle Fusion Vesicle Organization Membrane Organization Vesicle-mediated Transport Vesicle Docking Membrane Docking Establishment Of Localization In Cell Intracellular Transport Synaptic Vesicle Fusion To Presynaptic Membrane Cellular Localization Protein Transport Golgi Vesicle Transport Establishment Of Protein Localization Exocytosis Post-Golgi Vesicle-mediated Transport Transport Protein Localization Secretion By Cell Regulation Of Protein Localization To Plasma Membrane Synaptic Vesicle Exocytosis Intracellular Protein Transport Organelle Organization Secretion Regulation Of Cellular Localization Neurotransmitter Secretion Synaptic Vesicle Transport Cellular Protein Localization Regulation Of Cellular Component Organization Regulation Of Neurotransmitter Levels Regulation Of Exocytosis Neurotransmitter Transport Intra-Golgi Vesicle-mediated Transport Organelle Localization Platelet Activation Positive Regulation Of Exocytosis Establishment Of Vesicle Localization Regulation Of Protein Localization Endosomal Transport Vesicle Localization Retrograde Transport, Endosome To Golgi Synaptic Vesicle Docking Vesicle Fusion With Golgi Apparatus SNARE Complex Assembly Synaptic Vesicle Priming Regulation Of Hormone Secretion Regulation Of Body Fluid Levels ER To Golgi Vesicle-mediated Transport Synaptic Transmission
Tagcloud ?		cd3 ctls eliminate exocytosis granules granzymes groundwork laying lgs lytic nsf perforin snap snare snares stx13 stx16 stx3 stx4 stx6 stx7 synapse synapses syntaxin1b2 tumorigenic vamp3 vamp4 vesicle vti1b	account activate alter beta cat construct contains cotransfected delta demonstrating element half independence inducing neuroblastoma phenylacetate promoting ra rar rare re reporter retinoic sodium sv synergize synergy upregulating vector
Tagcloud (Difference) ?		cd3 ctls eliminate exocytosis granules granzymes groundwork laying lgs lytic nsf perforin snap snare snares stx13 stx16 stx3 stx4 stx6 stx7 synapse synapses syntaxin1b2 tumorigenic vamp3 vamp4 vesicle vti1b	account activate alter beta cat construct contains cotransfected delta demonstrating element half independence inducing neuroblastoma phenylacetate promoting ra rar rare re reporter retinoic sodium sv synergize synergy upregulating vector
Tagcloud (Intersection) ?